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Banxia **exin Decoction Alleviated Cerebral Glucose Metabolism Disorder by Regulating Intestinal Microbiota in APP/PS1 Mice
ObjectiveTo identify whether Banxia **exin Decoction (BXD) alleviates cerebral glucose metabolism disorder by intestinal microbiota regulation in...
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Roles of Gut Microbiota in Pathogenesis of Alzheimer’s Disease and Therapeutic Effects of Chinese Medicine
Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by progressive cognitive impairment. The pathogenesis of AD is...
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Electroacupuncture Alleviates Memory Deficits in APP/PS1 Mice by Targeting Serotonergic Neurons in Dorsal Raphe Nucleus
ObjectiveAlzheimer’s disease (AD) has become a significant global concern, but effective drugs able to slow down AD progression is still lacked....
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Metformin mitigates dementia risk among individuals with type 2 diabetes
This mini-narrative review explores the relationship between diabetes and dementia, focusing on the potential mitigating role of metformin in...
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Meta-analysis of the relationship between the number and location of perivascular spaces in the brain and cognitive function
BackgroundCerebral perivascular spaces are part of the cerebral microvascular structure and play a role in lymphatic drainage and the removal of...
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Total polyunsaturated fatty acid intake and the risk of non-alcoholic fatty liver disease in Chinese Han adults: a secondary analysis based on a case–control study
BackgroundPrevious studies have revealed obesity, nutrition, lifestyle, genetic and epigenetic factors may be risk factors for the occurrence and...
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Association between aspirin use and risk of dementia: a systematic review and meta-analysis
PurposeDementia and Alzheimer’s disease (AD) pose significant challenges to public health globally with no effective treatment strategies...
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Electroacupuncture Improves Blood-Brain Barrier and Hippocampal Neuroinflammation in SAMP8 Mice by Inhibiting HMGB1/TLR4 and RAGE/NADPH Signaling Pathways
ObjectiveTo investigate the molecular mechanisms underlying the beneficial effect of electroacupuncture (EA) in experimental models of Alzheimer’s...
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Neuro-nutraceuticals: Insights of experimental evidences and molecular mechanism in neurodegenerative disorders
BackgroundOne of the most important healthcare challenges in the world today is neurological disorders. Pose lifestyle changes are linked to a...
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Advancing Alzheimer’s care: a novel therapy with lecanemab
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects the patient’s quality of life. The current regime of drugs only...
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Evaluation of the prevention and treatment effects of acupuncture-moxibustion for Alzheimer disease based on various mouse models
ObjectiveTo evaluate the prevention and treatment effects of acupuncture-moxibustion for Alzheimer disease (AD) based on various AD mouse models.
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Examining the efficacy of the Mediterranean-DASH diet intervention for neurodegenerative delay in mitigating cognitive decline
BackgroundThe association between the Mediterranean-DASH (Dietary Approaches to Stop Hypertension) Diet Intervention for Neurodegenerative Delay...
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Olfactory Three-Needle Electroacupuncture Improved Synaptic Plasticity and Gut Microbiota of SAMP8 Mice by Stimulating Olfactory Nerve
ObjectiveTo investigate the effects and mechanisms of olfactory three-needle (OTN) electroacupuncture (EA) stimulation of the olfactory system on...
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Is dementia more likely following traumatic brain injury? A systematic review
BackgroundThe association between traumatic brain injury (TBI) and dementia is controversial, and of growing importance considering the ageing...
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Clinical Effectiveness of Muscarinic Receptor-Targeted Interventions in Neuropsychiatric Disorders: A Systematic Review
BackgroundFor decades, treatment of mood disorders, psychoses, anxiety and dementia have been confounded by limited efficacy and high rates of...
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Cognitive and psychological characteristics in patients with Cerebral Amyloid Angiopathy: a literature review
AimTo review the current data on cognitive and psychological characteristics of patients with CAA and on the instruments used for their evaluation.
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Chinese Medicine for Alzheimer's Disease: A Meta-Analysis of Randomized Controlled Trials
ObjectiveTo evaluate the effificacy of oral Chinese medicine (CM) in comparison with donepezil, a cholinesterase inhibitor (ChEI), for the treatment...
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Mechanisms of Electroacupuncture on Alzheimer’s Disease: A Review of Animal Studies
Alzheimer’s disease (AD) is the main type of dementia affecting elderly people. The medicines used for treating AD have limits in their ability to...
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The Effect of Religious-Spiritual Education and Care on the Life Quality of Iranian Elderly: A Systematic Review and Meta-Analysis
Aging causes the reduction in physical and physiological strength and an increase in the odds of affliction with chronic physical and mental...
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Effects of neighborhood built environment on cognitive function in older adults: a systematic review
BackgroundIn the background of an aging population, the risk of cognitive impairment in the older population is prominent. Exposure to complex...
