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2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation
In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most...
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Acute Biomechanical Effects of Empagliflozin on Living Isolated Human Heart Failure Myocardium
PurposeMultiple randomized controlled trials have presented SGLT2 inhibitors (SGLT2i) as novel pharmacological therapy for patients with heart...
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Renal denervation improves cardiac function independently of afterload and restores myocardial norepinephrine levels in a rodent heart failure model
Renal nerves play a critical role in cardiorenal interactions. Renal denervation (RDN) improved survival in some experimental heart failure (HF)...
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Changes in the shape and function of the fetal heart of pre- and gestational diabetes mothers
BackgroundHyperglycemia during pregnancy can affect fetal heart in many ways, including causing cardiac malformation, leading to hypertrophic...
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Myocardial Metabolism in Heart Failure
Purpose of ReviewMyocardial metabolism is intricately linked to cardiac function. Perturbations of cardiac energy metabolism result in an...
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The Echocardiographic Evaluation of the Right Heart: Current and Future Advances
Purpose of ReviewTo discuss physiologic and methodologic advances in the echocardiographic assessment of right heart (RH) function, including the...
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The athlete’s heart: insights from echocardiography
The manifestations of the athlete’s heart can create diagnostic challenges during an echocardiographic assessment. The classifications of the...
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Kinin-kallikrein system: New perspectives in heart failure
Heart failure (HF) is a pervasive clinical challenge characterized by compromised cardiac function and reduced quality of life. The kinin-kallikrein...
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Heart Failure: a Punch from the Gut
Purpose of ReviewThis article seeks to elucidate the mechanisms underlying the bidirectional relationship between the gut and the heart, focusing on...
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The heterocellular heart: identities, interactions, and implications for cardiology
The heterocellular nature of the heart has been receiving increasing attention in recent years. In addition to cardiomyocytes as the prototypical...
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Single-Beat Estimation of Ventricular Contractility
Pressure-volume loops and the end-systolic pressure-volume relationship ( E max and V 0 ) are important measures of biventricular function. To overcome...
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Association of insulin use with LV remodeling and clinical outcomes in diabetic patients with heart failure and reduced ejection fraction: assessed by cardiac MRI
BackgroundInsulin is commonly used in type 2 diabetes mellitus (T2DM) to achieve glycemic control. However, recent evidence showed that insulin use...
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Right heart failure in left heart disease: imaging, functional, and biochemical aspects of right ventricular dysfunction
For decades, cardiologists have largely underestimated the role of the right heart in heart failure due to left heart disease. Nowadays, the...
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Triple repeated fetal congenital heart disease linked to PLD1 mutation: a case report
BackgroundCongenital heart disease occurs in approximately 1 in 100 cases. Although sibling occurrence is high (3–9%), the causative genes for this...
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Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has poor reparative potential....
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Repurposing Probenecid for the Treatment of Heart Failure (Re-Prosper-HF): a study protocol for a randomized placebo-controlled clinical trial
BackgroundImproving contractility in heart failure with reduced ejection fraction (HFrEF) has resurfaced as a potential treatment goal. Inotropic...
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Expanding Donor Heart Utilization Through Machine Perfusion Technologies
Purpose of ReviewRecent advances in donor heart preservation have allowed the utilization of hearts that would typically be discarded due to...
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Immunomodulation and immunopharmacology in heart failure
The immune system is intimately involved in the pathophysiology of heart failure. However, it is currently underused as a therapeutic target in the...
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Stroke–heart syndrome: current progress and future outlook
Stroke can lead to cardiac complications such as arrhythmia, myocardial injury, and cardiac dysfunction, collectively termed stroke–heart syndrome...
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Impact of Sex and Diabetes in Patients with Heart Failure
Purpose of reviewHeart failure (HF) is a complex clinical syndrome with a growing global health burden. This review explores the intersection of HF,...
