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Gut inflammation and tumorigenesis: every site has a different tale to tell
Gut inflammation has been correlated with cancerogenesis by disrupting gastrointestinal homeostasis. Numerous chronic inflammatory disorders of the...
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Determination of an Appropriate Endoscopic Monitoring Interval for Patients with Gastric Precancerous Conditions in China
ObjectiveGastric precancerous conditions such as atrophic gastritis (AG) and intestinal metaplasia (IM) are considered independent risk factors for...
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The prognostic and potentially immunomodulatory role of cartilage oligomeric matrix protein in patients with gastric and esophageal adenocarcinoma
BackgroundCartilage oligomeric matrix protein (COMP) is a novel regulator of the tumor microenvironment. Studies in colon cancer and pancreatobiliary...
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The immune microenvironment in gastric adenocarcinoma
Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma (GAC) consists of a variety of stromal cell types,...
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microRNA-128-3p inhibits proliferation and accelerates apoptosis of gastric cancer cells via inhibition of TUFT1
ObjectiveGastric cancer (GC) is a malignant tumor rooting in the gastric mucosal epithelium, ranking the first among various malignant tumors....
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Lymphangiogenesis in gastric cancer: function and mechanism
Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's...
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When rare diseases crisscross within the same patient: von Hippel-Lindau and type 1 gastric neuroendocrine tumor
Von-Hippel-Lindau (VHL) is a genetic multisystem disorder characterized by visceral cysts and benign and malignant tumors in various organs. Herein,...
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The correlation between the main and minor lesions of synchronous multiple gastric neoplasms assessed gastroscopically and microscopically
BackgroundPatients with early gastric cancer (EGC) are at high risk of develo** synchronous multiple gastric neoplasms (SMGNs) after undergoing...
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Primary duodenal carcinoma suspected to arise from ectopic gastric mucosa: a case report
BackgroundEctopic gastric mucosa mainly occurs in the duodenal bulb, and its etiology is thought to be congenital straying of gastric tissues....
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Tubulovillous adenoma with high-grade dysplasia of the vulva harboring high tumor mutational burden and cancer-associated mutations: a case report
BackgroundVulvar cancer is a rare disease, accounting for approximately 5% of gynecological malignancies. Primary adenocarcinoma of intestinal-type...
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Novel mutations in a second primary gastric cancer in a patient treated for primary colon cancer
A 60-year-old man presented with complaints of abdominal pain and melena. Patient had a history of colon cancer 16 years back and had undergone right...
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Development of an artificial intelligent model for pre-endoscopic screening of precancerous lesions in gastric cancer
BackgroundGiven the high cost of endoscopy in gastric cancer (GC) screening, there is an urgent need to explore cost-effective methods for the...
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The extracellular matrix protein EMILIN-1 impacts on the microenvironment by hampering gastric cancer development and progression
BackgroundThe contribution of the tumor microenvironment and extracellular matrix to the aggressive biology of Gastric Cancer (GC) has been recently...
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FPR1 Antagonist (BOC-MLF) Inhibits Amniotic Epithelial-mesenchymal Transition
ObjectivePremature rupture of membranes (PROM) is a common pregnancy disorder that is closely associated with structural weakening of fetal...
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Genomic susceptibility to gastric cancer in Northwest Iran: population-based and case–control studies
IntroductionThe age-standardized incidence rate for gastric cancer is estimated to be 11.1% worldwide and 39.1% for Ardabil province in northwest...
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Coexistence of early gastric cancer and benign submucosal lesions mimic invasive cancer: a retrospective multicenter experience
ObjectiveTo present a study to identify the characteristics of coexisting early gastric cancer (EGC) and benign submucosal lesions, with the aim of...
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Predictive biomarkers in gastric cancer
Predictive biomarkers are the mainstay of precision medicine. This review summarizes the advancements in tissue-based diagnostic biomarkers for...
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Risk factors associated with recurrence of gastric hyperplastic polyps: a single-center, long-term, retrospective cohort study
BackgroundThe likelihood of recurrence of gastric hyperplastic polyps (GHPs) following endoscopic resection and the need for long-term follow-up...
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Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease
BackgroundGastric carcinoma (GC) is uncommon in dogs, except in predisposed breeds such as Belgian Shepherd dogs (BSD) of the Tervuren and...
