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Imaging the optic nerve with optical coherence tomography
Optical coherence tomography (OCT) is a non-invasive imaging technology, which may be used to generate in vivo quantitative and qualitative measures...
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Thinning of the inner and outer retinal layers, including the ganglion cell layer and photoreceptor layers, in obstructive sleep apnea and hypopnea syndrome unrelated to the disease severity
PurposeThe aim of this study was to analyze the segmented layers of the macula in patients with obstructive sleep apnea and hypopnea syndrome (OSAS)...
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Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway
PurposeWe aim to investigate the effect of Park7 on mice RGC survival and function following optic nerve crush (ONC), and to explore its potential...
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Role of T cell-induced autoimmune response in the pathogenesis of glaucoma
PurposeThis review aims to elucidate the role of T cell-induced autoimmune responses in the pathogenesis of glaucoma, focusing on the immunological...
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Baricitinib ameliorates inflammatory and neuropathic pain in collagen antibody-induced arthritis mice by modulating the IL-6/JAK/STAT3 pathway and CSF-1 expression in dorsal root ganglion neurons
BackgroundJanus kinase (JAK) inhibitors, such as baricitinib, are widely used to treat rheumatoid arthritis (RA). Clinical studies show that...
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Mast cell stabilizer, an anti-allergic drug, reduces ventricular arrhythmia risk via modulation of neuroimmune interaction
Mast cells (MCs) are important intermediates between the nervous and immune systems. The cardiac autonomic nervous system (CANS) crucially modulates...
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Macular vessel density versus ganglion cell complex thickness for detection of early primary open-angle glaucoma
BackgroundTo evaluate the macular vessel density (VD) and ganglion cell complex (GCC) thickness in pre-perimetric (PPG) and early perimetric primary...
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Macular ganglion-cell-complex layer thinning and optic nerve integrity in drug-naïve Parkinson’s disease
To reveal the macular inner retinal change linked to axonal degeneration in Parkinson’s disease (PD), we performed macular optical coherence...
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Macular ganglion cell complex thinning in children with visual field defects due to central nervous system pathology
PurposeTo study the relationship between macular ganglion cell complex (GCC) thickness and visual field defects (VFD) caused by central nervous...
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7,8-Dihydroxyflavone protects retinal ganglion cells against chronic intermittent hypoxia-induced oxidative stress damage via activation of the BDNF/TrkB signaling pathway
PurposeChronic intermittent hypoxia (CIH) plays a key role in the complications of obstructive sleep apnea (OSA), which is strongly associated with...
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Traumatic optic neuropathy-associated progressive thinning of the retinal nerve fiber layer and ganglion cell complex: two case reports
BackgroundTraumatic optic neuropathy (TON) is a form of optic nerve injury that occurs secondary to trauma and is etiologically associated with acute...
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Subependymal giant cell astrocytoma as presentation of tuberous sclerosis: a case report
BackgroundA case of tuberous sclerosis patient on long-term follow-up is reported here.
Case presentationA 22-year-old female patient with epilepsy...
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Choroidal thickness and the retinal ganglion cell complex in chronic Leberʼs hereditary optic neuropathy: a prospective study using swept-source optical coherence tomography
Background/ObjectivesChoroidal thinning has been suggested in Leber’s hereditary optic neuropathy (LHON). No study has been conducted of the choroid...
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Complex Regional Pain Syndrome: Evidence-Based Advances in Concepts and Treatments
Purpose of ReviewThis review presents the most current information about the epidemiology of complex regional pain syndrome (CRPS), classification...
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Ganglion cell layer thickening in patients suffering from Obstructive Sleep Apnea–Hypopnea syndrome with long Mean Apnea–Hypopnea Duration during sleep
PurposeTo study the effects of mean apnea–hypopnea duration (MAD), a useful indicator of blood oxygenation, on peripapillary retinal nerve fiber...
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Efficacy of conditioned autologous serum therapy (Orthokine®) on the dorsal root ganglion in patients with chronic radiculalgia: study protocol for a prospective randomized placebo-controlled double-blind clinical trial (RADISAC trial)
BackgroundPulsed radiofrequency (PRF) treatment on the dorsal root ganglion (DRG) has been proposed as a good option for the treatment of persistent...
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Comparison of the retinal nerve fiber layer and ganglion cell complex thickness in Korean patients with unilateral exfoliation syndrome and healthy subjects
PurposeTo compare retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with unilateral exfoliation syndrome (XFS)...
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Hirschsprung’s disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3β
BackgroundN6-methyladenosine (m6A) is the most abundant mRNA modification in mammals, participating in various biological processes. VIRMA is a key...
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A Review of Perifoveal Exudative Vascular Anomalous Complex
Purpose of ReviewIn this article, we review the current literature regarding a rare entity, perifoveal exudative vascular anomalous complex (PEVAC).
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Roles of Optineurin and Extracellular Vesicles in Glaucomatous Retinal Cell Loss
ObjectiveTo explore the role of extracellular vesicles (EVs) in the pathogenesis of glaucoma caused by E50K mutation.
MethodsA photoreceptor cell...