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Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems
BackgroundQuantitative SPECT imaging in targeted radionuclide therapy with lutetium-177 holds great potential for individualized treatment based on...
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Comprehensive SPECT/CT system characterization and calibration for 177Lu quantitative SPECT (QSPECT) with dead-time correction
BackgroundPersonalization of 177 Lu-based radionuclide therapy requires implementation of dosimetry methods that are both accurate and practical...
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Diagnostic performance of the specific uptake size index for semi-quantitative analysis of I-123-FP-CIT SPECT: harmonized multi-center research setting versus typical clinical single-camera setting
IntroductionThe specific uptake size index (SUSI) of striatal FP-CIT uptake is independent of spatial resolution in the SPECT image, in contrast to...
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Determination of gamma camera calibration factors for quantitation of therapeutic radioisotopes
BackgroundCamera calibration, which translates reconstructed count map into absolute activity map, is a prerequisite procedure for quantitative SPECT...
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The clinical value of xSPECT/CT Bone versus SPECT/CT. A prospective comparison of 200 scans
PurposeTo prospectively evaluate the clinical utility of xSPECT/CT Bone, a new reconstruction algorithm for single photon emission tomography...
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CT-based SPECT attenuation correction and assessment of infarct size: results from a cardiac phantom study
RationaleMyocardial perfusion SPECT is a commonly performed, well established, clinically useful procedure for the management of patients with...
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18F-Fluorocholine PET/CT in the assessment of primary hyperparathyroidism compared with 99mTc-MIBI or 99mTc-tetrofosmin SPECT/CT: a prospective dual-centre study in 100 patients
PurposeIn this prospective study we compared the accuracy of 18 F-fluorocholine PET/CT with that of 99m Tc-MIBI or 99m Tc-tetrofosmin SPECT/CT in the...
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Ejection fraction in myocardial perfusion imaging assessed with a dynamic phantom: comparison between IQ-SPECT and LEHR
BackgroundDevelopments in single photon emission tomography instrumentation and reconstruction methods present a potential for decreasing acquisition...
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The added value of SPECT-CT for the identification of sentinel lymph nodes in early stage oral cancer
PurposeTo assess the role of single-photon emission computed tomography with computed tomography (SPECT-CT) for the identification of sentinel lymph...
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Differences in polar-map patterns using the novel technologies for myocardial perfusion imaging
BackgroundNew technologies are available in MPI. Our aim was to evaluate their impact on the uniformity of normal myocardial uptake in the polar-map...
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Prognostic value of lower limb perfusion single-photon emission computed tomography-computed tomography in patients with lower limb atherosclerotic peripheral artery disease
PurposeThe purpose of this study was to estimate the severity of the participants’ lower limb ischemia by calculating the lower limb...
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Successful innovation: A time for change?
Innovation plays an important role in the advancement of nuclear cardiology, meeting the need for reduced exposure to radiation, and maintaining and...
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Dose reduction in half-time myocardial perfusion SPECT-CT with multifocal collimation
BackgroundRecent technological advances in myocardial perfusion imaging may warrant the use of lower injected activity. We evaluated whether...
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Longitudinal analysis of bone metabolism using SPECT/CT and 99mTc-diphosphono-propanedicarboxylic acid: comparison of visual and quantitative analysis
BackgroundThe therapy response of osseous metastases (OM) is commonly monitored by bone scintigraphies (BS). The aim of this study was to compare...