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Relationship between sarcopenia and fatty liver in middle-aged and elderly patients with type 2 diabetes mellitus
ObjectiveIn this study, we investigated the relationship between sarcopenia and fatty liver in middle-aged and elderly patients diagnosed with type 2...
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Intrinsic differences in rod and cone membrane composition: implications for cone degeneration
PurposeIn many retinal pathological conditions, rod and cone degeneration differs. For example, the early-onset maculopathy Stargardts disease type 1...
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Paraspinal muscle degeneration and lower bone mineral density as predictors of proximal junctional kyphosis in elderly patients with degenerative spinal diseases: a propensity score matched case–control analysis
Study designRetrospective case–control study.
ObjectivesProximal junctional kyphosis (PJK) is a postoperative complication involving the proximal...
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Metabolic Dysfunction-associated fatty liver disease and incident heart failure risk: the Kailuan cohort study
BackgroundRecently, metabolic dysfunction-associated fatty liver disease (MAFLD) has been proposed to replace non-alcoholic fatty liver disease...
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May the prognostic nutritional index (PNI) play a role in predicting age-related macular degeneration?
AimIt is known that a healthy and balanced diet plays an important role in the etiopathogenesis of age-related macular degeneration (AMD). The aim of...
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Changes in the composition of the fecal metabolome and gut microbiota contribute to intervertebral disk degeneration in a rabbit model
PurposeLower back pain (LBP), mainly caused by intervertebral disk (IVD) degeneration (IDD), is widely prevalent worldwide and is a serious...
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Elevated Kallistatin promotes the occurrence and progression of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and the development of non-alcoholic steatohepatitis...
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Current Data on the Age-Related Macular Degeneration Pathophysiology: Focus on Growth Factors and Neurotrophins
AbstractAge is a main risk factor for age-related macular degeneration (AMD), a complex multifactorial neurodegenerative retinal disease that is...
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Muscle spindles of the multifidus muscle undergo structural change after intervertebral disc degeneration
PurposeProprioceptive deficits are common in low back pain. The multifidus muscle undergoes substantial structural change after back injury, but...
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Sex-specific differences in ectopic fat and metabolic characteristics of paediatric nonalcoholic fatty liver disease
Background/ObjectivesSex-specific differences in obesity-related metabolic characteristics of non-alcoholic fatty liver disease (NAFLD) have rarely...
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CT-based methods for assessment of metabolic dysfunction associated with fatty liver disease
Metabolic dysfunction-associated fatty liver disease (MAFLD), previously called metabolic nonalcoholic fatty liver disease, is the most prevalent...
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Efficacy of Sitagliptin on Nonalcoholic Fatty Liver Disease in High-fat-diet-fed Diabetic Mice
ObjectiveNonalcoholic fatty liver disease (NAFLD) is a common cause of clinical liver dysfunction and an important prepathological change of liver...
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The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk
Long-chain polyunsaturated fatty acids (LC-PUFAs) are obtained from diet or derived from essential shorter-chain fatty acids, and are crucial for...
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Abdominal aortic calcification is independently associated with increased atrophy and fatty infiltration of the lumbar paraspinal muscles: a retrospective cross-sectional study
BackgroundAortic abdominal calcification (AAC) is associated with spine-related conditions, such as lower back pain and reduced bone mineral density....
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Interaction between genetics and the adherence to the Mediterranean diet: the risk for age-related macular degeneration. Coimbra Eye Study Report 8
BackgroundAge-related macular degeneration (AMD) is a multifactorial degenerative disease of the macula. Different factors, environmental, genetic...
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Metformin increases the expression of proinflammatory cytokines and inhibits supraspinatus fatty infiltration
BackgroundAfter a rotator cuff (RC) tendon tear, the supraspinatus (SS) inflammatory response induces fatty infiltration (FI). Metformin has the...
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Evidence for Genetic Causal Relationships Between Multiple Immune-Mediated Inflammatory Diseases and Age-Related Macular Degeneration: A Univariable and Multivariable Mendelian Randomization Study
IntroductionWith the global aging population on the rise, age-related macular degeneration (AMD) poses a growing healthcare burden. Prior research...
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Butyrate: More Than a Short Chain Fatty Acid
Purpose of ReviewThe mechanistic understanding of the importance and the potential benefits of the gut microbiome has exploded in potential roles in...
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Systematic review and meta-analysis of mass spectrometry proteomics applied to ocular fluids to assess potential biomarkers of age-related macular degeneration
BackgroundAge-related macular degeneration (AMD) is a significant cause of severe vision loss. The main purpose of this study was to identify mass...
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The relationship between the degeneration and asymmetry of the lumbar multifidus and erector spinae muscles in patients with lumbar disc herniation with and without root compression
BackgroundThe determination of muscle pathologies in lumbar disc herniation (LDH) and other conditions with low back pain is important for...
