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Comparing Achievement of National Psoriasis Foundation Treatment Targets among Patients with Plaque Psoriasis Treated with Ixekizumab versus Other Biologics in Clinical and Real-World Studies
IntroductionThe National Psoriasis Foundation (NPF) recommends evaluating patient response to treatment at week 12, with a target response of ≤ 1%...
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Effects of low-frequency repetitive transcranial magnetic stimulation combined with cerebellar continuous theta burst stimulation on spasticity and limb dyskinesia in patients with stroke
BackgroundRepetitive transcranial magnetic stimulation (rTMS) has been reported to treat muscle spasticity in post-stroke patients. The purpose of...
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Neurobiomechanical mechanism of Tai Chi to improve upper limb coordination function in post-stroke patients: a study protocol for a randomized controlled trial
BackgroundUpper limb dysfunction seriously affects the ability of stroke patients to perform activities of daily living. As a popular exercise...
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Effects of programmed flexor–extensor alternating electrical acupoint stimulation on upper limb motor functional reconstruction after stroke: study protocol for a double-blind, randomized controlled trial
BackgroundStroke’s prevalence and morbidity are increasing (Guano, et al. Neuro 89:53–61, 2017), and limb motor dysfunction is left in most patients...
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Upper limb practice with a dynamic hand orthosis to improve arm and hand function in people after stroke: a feasibility study
BackgroundDynamic hand orthosis may help upper limb recovery by kee** the wrist and hand in an optimal position while executing a grasp. Our aim...
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Baseline Characteristics and mNAPSI Change from Baseline Scores Through Month 12 for Patients with Moderate-to-Severe Plaque Psoriasis and Concomitant Nail Psoriasis Treated with Biologics from PSoHO
IntroductionNail psoriasis is highly prevalent among patients with psoriasis yet remains one of the most challenging areas to treat. To better...
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Custom TKA combined with personalised coronal alignment yield improvements that exceed KSS substantial clinical benefits
PurposeThe purpose of this study was to report Knee Society Scores (KSS) at 12-month follow-up in a series of 266 knees that received custom TKA. The...
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The Effectiveness of the Contralaterally Controlled Functional Electrical Stimulation in Post-stroke Patients: a Systematic Review
Purpose of ReviewThis systematic review of randomized controlled trials (RCTs) aimed to systematically evaluate the findings of the randomized...
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Effectiveness of robot-assisted virtual reality mirror therapy for upper limb motor dysfunction after stroke: study protocol for a single-center randomized controlled clinical trial
BackgroundUpper limb motor dysfunction is a common sequela of stroke, and its clinical efficacy needs to be improved. This protocol describes a trial...
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Comparative Effectiveness, Time to Discontinuation, and Patient-Reported Outcomes with Baricitinib in Rheumatoid Arthritis: 2-Year Data from the Multinational, Prospective Observational RA-BE-REAL Study in European Patients
IntroductionRA-BE-REAL is a 3-year, multinational, prospective, observational study of adult patients with rheumatoid arthritis (RA) evaluating time...
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Evolution and prediction of mismatch between observed and perceived upper limb function after stroke: a prospective, longitudinal, observational cohort study
BackgroundA previously shown ‘mismatch’ group of patients with good observed upper limb (UL) motor function but low perceived UL activity at six...
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Effects of acupuncture combined with Brunnstrom staging on upper-limb motor function, cerebral arterial blood flow velocity, and brain function remodeling after stroke
ObjectiveTo explore the effects of acupuncture combined with Brunnstrom staging on upper-limb motor function, cerebral arterial blood flow velocity,...
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Effects of a remote-handling-concept–based task-oriented arm training (ReHab-TOAT) on arm-hand skill performance in chronic stroke: a study protocol for a two-armed randomized controlled trial
BackgroundImproving arm-hand skill performance is a major therapeutic target in stroke rehabilitation and needs intensive and varied training....
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Functional Near-Infrared Spectroscopy as a Target Navigator for rTMS Modulation in Patients with Hemiplegia: A Randomized Control Study
IntroductionAlthough repetitive transcranial magnetic stimulation (rTMS) is efficacious for motor neuromodulation in stroke survivors, high...
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Long-term recovery of upper limb motor function and self-reported health: results from a multicenter observational study 1 year after discharge from rehabilitation
BackgroundImpaired motor functions after stroke are common and negatively affect patients' activities of daily living and quality of life. In...
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EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and clinical application
Stroke is one of the most serious diseases that threaten human life and health. It is a major cause of death and disability in the clinic. New...
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High-density transcranial direct current stimulation to improve upper limb motor function following stroke: study protocol for a double-blind randomized clinical trial targeting prefrontal and/or cerebellar cognitive contributions to voluntary motion
BackgroundFocal brain lesions following a stroke of the middle cerebral artery induce large-scale network disarray with a potential to impact...
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Protocol for a single-blind randomized clinical trial to test the efficacy of bilateral transcranial magnetic stimulation on upper extremity motor function in patients recovering from stroke
BackgroundNo consensus currently exists regarding the optimal protocol for repetitive transcranial magnetic stimulation (rTMS) treatment of...
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The Effect of Customized and Silicon Insoles on Mid- and Hindfoot in Adult Flexible Pes Planovalgus
BackgroundFlexible flat foot or pes planovalgus is a common foot deformity, and silicone and customized insole are commonly used as a non-operative...
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Screening and determinant of suspected developmental delays among Egyptian preschool-aged children: a cross-sectional national community-based study
BackgroundEarly childhood life is critical for optimal development and is the foundation of future well-being. Genetic, sociocultural, and...
