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Successful conversion surgery following chemotherapy with an immune checkpoint inhibitor in an older adult patient with stage IVB esophageal squamous cell carcinoma: a case report
BackgroundChemotherapy and chemoradiotherapy are common treatments for esophageal squamous cell carcinoma with distant metastasis; however, the...
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Knockdown of RAD51AP1 suppressed cell proliferation and invasion in esophageal squamous cell carcinoma
BackgroundEsophageal cancer is a common malignant tumor of digestive tract with esophageal squamous cell carcinoma (ESCC) being the main histological...
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Outcomes of solitary postoperative recurrence of esophageal squamous cell carcinoma diagnosed with FDG-PET/CT and treated with definitive radiation therapy
BackgroundSurgical resection of esophageal cancer is frequently performed to achieve a complete cure. However, the postoperative recurrence rate is...
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Prognostic impact of perioperative change in serum p53 antibody titers in esophageal squamous cell carcinoma
BackgroundThe clinical effectiveness of tumor markers for estimating prognosis in esophageal squamous cell carcinoma (ESCC) remains unclear. We...
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GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal squamous cell carcinoma
Treating patients with esophageal squamous cell carcinoma (ESCC) is challenging due to the high chemoresistance. Growth differentiation factor 15...
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Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis
Esophageal squamous cell carcinoma (ESCC) is a prevalent malignancy of the digestive system. Hypoxia is a crucial player in tumor ferroptosis...
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KLF5 promotes esophageal squamous cell cancer through the transcriptional activation of FGFBP1
Krüpple-like factor 5 (KLF5) is a zinc-finger-containing transcription factor implicated in several human malignancies, but its potential regulatory...
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COL8A1 Regulates Esophageal Squamous Carcinoma Proliferation and Invasion Through PI3K/AKT Pathway
PurposeEsophageal squamous carcinoma (ESCC) is a gastrointestinal malignancy with a high mortality, but the tumorigenesis is still unclear,...
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Baseline and interim [18F]FDG-PET/MRI to assess treatment response and survival in patients with M0 esophageal squamous cell carcinoma treated by curative-intent therapy
BackgroundTo investigate the value of [18F]FDG-PET/MRI in predicting treatment response and survival in patients with primary M0 esophageal squamous...
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Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma
Current clinical therapies targeting receptor tyrosine kinases including focal adhesion kinase (FAK) have had limited or no effect on esophageal...
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Long-term survival after pulmonary metastasectomy in patients with esophageal squamous cell carcinoma with lung metastasis
ObjectivesEsophageal squamous cell carcinoma with pulmonary metastasis has a poor prognosis, and the only treatment modality is systemic therapy such...
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Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report
BackgroundLiposarcoma is one of the most common soft tissue sarcomas, but is extremely rarely found in the esophagus. There have been no reports of...
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Roles of oncogenes in esophageal squamous cell carcinoma and their therapeutic potentials
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer (EC) in Asia. It is a malignant digestive tract tumor with...
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Clinicopathological and mutational analysis of esophageal basaloid squamous cell carcinoma
Esophageal basaloid squamous cell carcinoma (EBSCC) is a poorly differentiated variant of esophageal squamous cell carcinoma (ESCC). We aimed to...
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Decoding tumor stage by peritumoral and intratumoral radiomics in resectable esophageal squamous cell carcinoma
PurposeTo evaluate the potential application of radiomics in predicting Tumor-Node-Metastasis (TNM) stage in patients with resectable esophageal...
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Impact of Delaying Surgery After Chemoradiation on Outcomes for Locally Advanced Esophageal Squamous Cell Carcinoma
BackgroundPerforming selective esophagectomy for locally advanced squamous cell carcinoma may spare patients morbidity, but delayed surgery may infer...
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A risk prognostic model for patients with esophageal squamous cell carcinoma basing on cuproptosis and ferroptosis
BackgroundCuproptosis, a form of copper-dependent programmed cell death recently presented by Tsvetkov et al., have been identified as a potential...
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Laparoscopic versus open abdominal lymph node dissection for esophageal squamous cell carcinoma: a propensity score matching analysis
PurposeTo compare the short- and long-term outcomes of laparoscopic and open abdominal lymph node dissection using propensity score matching (PSM)...
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Clinical Significance of Intramural Metastasis as an Independent Prognostic Factor in Esophageal Squamous Cell Carcinoma
BackgroundAlthough intramural metastasis (IM) in esophageal cancer is considered a poor prognostic factor, there are only limited reports detailing...
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Exosomal PIK3CB promotes PD-L1 expression and malignant transformation in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC), which accounts for 90% of esophageal carcinomas, seriously endangers human health. Worse still, the 5-year...
