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Association between serum insulin-like growth factor 1 and osteoporosis risk in Parkinson's disease: a cross-sectional study
ObjectiveTo examine the correlation between serum insulin-like growth factor 1 (IGF-1) and osteoporosis (OP) in Parkinson's disease (PD).
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Physical activity as risk factor in amyotrophic lateral sclerosis: a systematic review and meta-analysis
ObjectiveAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with rapid progression and high mortality. Physical activity (PA)...
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Environmental risk factors of type 2 diabetes—an exposome approach
Type 2 diabetes is one of the major chronic diseases accounting for a substantial proportion of disease burden in Western countries. The majority of...
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Environmental risk factors in multiple sclerosis: bridging Mendelian randomization and observational studies
Multiple sclerosis (MS) is a complex disease with both genetic variants and environmental factors involved in disease susceptibility. The main...
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Is headache a risk factor for dementia? A systematic review and meta-analysis
ObjectiveIn this systematic review and meta-analysis, we critically evaluate available evidence regarding the association between primary headaches...
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Impacts of residential indoor air quality and environmental risk factors on adult asthma-related health outcomes in Chicago, IL
BackgroundResidential environments are known to contribute to asthma.
ObjectiveTo examine the joint impacts of exposures to residential indoor and...
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Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis: recruitment challenges, potential bias, and statistical strategies
It is unknown whether the currently known risk factors of multiple sclerosis reflect the etiology of progressive-onset multiple sclerosis (POMS) as...
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Estimating the risk of environmental contamination by forest users in African Swine Fever endemic areas
BackgroundAfrican Swine Fever (ASF) is a highly lethal viral disease caused by the African Swine Fever Virus (ASFV), the only virus of the Asfaviridae ...
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Obstetric care for environmental migrants
BackgroundMigration due to environmental factors is an international crisis affecting many nations globally. Pregnant people are a vulnerable...
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The role of environmental and seasonal factors in spine deep surgical site infection: the air pollution, a factor that may be underestimated
BackgroundDifferent strategies have been described in order to reduce spine deep surgical site infection (SSI); however, non-intervenable items such...
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Effect of risk factor-tailored autonomy enhancement education in the first-time middle-aged patients undergoing percutaneous coronary intervention: a randomized controlled trial
PurposeIt is important for middle-aged patients who have undergone acute treatment for coronary artery disease to voluntarily improve their lifestyle...
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Environmental and clinical data utility in pediatric asthma exacerbation risk prediction models
BackgroundAsthma exacerbations are triggered by a variety of clinical and environmental factors, but their relative impacts on exacerbation risk are...
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Inflammation, metabolic dysregulation and environmental neurotoxins and risk of cognitive decline and impairment in midlife
BackgroundAge-related declines in cognitive function may begin in midlife.
PurposeTo determine whether blood-based biomarkers of inflammation,...
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Genetics of environmental sensitivity and its association with variations in emotional problems, autistic traits, and wellbeing
Greater environmental sensitivity has been associated with increased risk of mental health problems, especially in response to stressors, and lower...
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The HIV Environmental Riskscape: The Roles of HIV Sexual Risk and Resilience Factors among Black Men Who Have Sex with Men: Findings from the Real Talk Project
Black and African American men who have sex with men (Black MSM) experience the greatest proportion of new HIV infections in the United States. To...
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Polygenic risk score and biochemical/environmental variables predict a low-risk profile of age-related macular degeneration in Sardinia
PurposeTo ascertain the prevalence and clinical and genetic features of age-related macular degeneration (AMD) in subjects living in the Lanusei...
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Association of obesity and menarche SNPs and interaction with environmental factors on precocious puberty
BackgroundObesity is an important cause for the precocious or early puberty. However, the association between obesity-related loci and the risk of...
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Epigenetics and environmental health
Epigenetic modifications including DNA methylation, histone modifications, chromatin remodeling, and RNA modifications complicate gene regulation and...
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Vascular Endothelial Growth Factor and Ischemic Stroke Risk: A Mendelian Randomization Study
IntroductionPrevious studies have reported controversial relationships between circulating vascular endothelial growth factors (VEGF) and ischemic...