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Moniezia benedeni drives the SNAP-25 expression of the enteric nerves in sheep's small intestine
BackgroundThe neuroimmune network plays a crucial role in regulating mucosal immune homeostasis within the digestive tract. Synaptosome-associated...
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Microbiota-Gut-Brain Axis in Psychiatry: Focus on Depressive Disorders
Purpose of ReviewGut microbiota contribute to several physiological processes in the host. The composition of the gut microbiome is associated with...
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The Brain–Gut Axis in Traumatic Brain Injury: Implications for Nutrition Support
Purpose of ReviewEarly enteral nutrition improves outcomes following traumatic brain injury (TBI). This can prove difficult due to TBI-induced...
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The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys
Neurological manifestations are frequently reported in the COVID-19 patients. Neuromechanism of SARS-CoV-2 remains to be elucidated. In this study,...
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The P2Y1 receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation
This study was designed to explore the expression changes of P2Y 1 receptors in the distal colonic myenteric layer of rats. An opioid induced...
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Research progress on intestinal microbiota regulating cognitive function through the gut-brain axis
The intestinal microbiota community is a fundamental component of the human body and plays a significant regulatory role in maintaining overall...
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Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes
AimsThe purpose of this review is to explore the interconnected pathways of the microbiota-gut-brain axis (MGBA), focusing on the roles of the vagus...
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Neurotransmitter signaling: a new frontier in colorectal cancer biology and treatment
The brain–gut axis, a bidirectional network between the central and enteric nervous system, plays a critical role in modulating the gastrointestinal...
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The nerve cells in gastrointestinal cancers: from molecular mechanisms to clinical intervention
Gastrointestinal (GI) cancer is a formidable malignancy with significant morbidity and mortality rates. Recent studies have shed light on the complex...
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Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome
The management of visceral pain in patients with disorders of gut–brain interaction, notably irritable bowel syndrome, presents a considerable...
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Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats
ObjectiveThe aim of this study was to detect the expression of interleukin (IL)-1β and transforming growth factor (TGF)-β1 in the colonic tissue and...
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The neurobiology of irritable bowel syndrome
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that affects between 5 and 10% of the general population...
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The ‘α-synucleinopathy syndicate’: multiple system atrophy and Parkinson’s disease
Multiple System Atrophy (MSA) and Parkinson’s diseases (PD) are elite members of the α-synucleinopathy organization. Aberrant accumulations of the...
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Vagus nerve stimulation as a therapeutic option in inflammatory rheumatic diseases
The vagus nerve forms intricate neural connections with an extensive number of organs, particularly the digestive system. The vagus nerve has a...
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Cross-diagnostic determinants of cognitive functioning: the muscarinic cholinergic receptor as a model system
Cognitive impairment is a predictor of disability across different neuropsychiatric conditions, and cognitive abilities are also strongly related to...
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Migraine and Gastroparesis
Purposeof ReviewMigraine is a chronic and disabling disease affecting a significant proportion of the world’s population. There is evidence that...
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High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung’s disease
PurposeHirschsprung’s disease (HSCR) is the leading cause of neonatal functional intestinal obstruction, which has been identified in many familial...
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Gut Microbiota Modulation and Its Implications on Neuropathic Pain: A Comprehensive Literature Review
Neuropathic pain (NP) is a chronic pain disorder arising from somatosensory nervous system impairment. Extensive evidence supports the notion that...
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Issues for patchy tissues: defining roles for gut-associated lymphoid tissue in neurodevelopment and disease
Individuals diagnosed with neurodevelopmental conditions such as autism spectrum disorder (ASD; autism) often experience tissue inflammation as well...
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The brain-first vs. body-first model of Parkinson’s disease with comparison to alternative models
The ultimate origin of Lewy body disorders, including Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB), is still incompletely understood....
