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Exploring the reciprocal relationship between activities of daily living disability and depressive symptoms among middle-aged and older Chinese people: a four-wave, cross-lagged model
BackgroundEarly studies have shown a relationship between activities of daily living (ADL) disability and depressive symptoms in older people....
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Association of demographics, cardiovascular indicators and disability characteristics with 7-year coronary heart disease incident in persons with disabilities
ObjectivePrevious studies had demonstrated that disability increases mortality in patients with coronary heart disease (CHD). However, for people who...
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Multicenter external validation of prediction models for clinical outcomes after spinal fusion for lumbar degenerative disease
BackgroundClinical prediction models (CPM), such as the SCOAP-CERTAIN tool, can be utilized to enhance decision-making for lumbar spinal fusion...
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Predicting disability retirement among Abu Dhabi police using multiple measure of sickness absence
BackgroundDisability retirement has been investigated in the last two decades using predictors such as measures of sickness absence, psychological,...
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Clinical genomics expands the link between erroneous cell division, primary microcephaly and intellectual disability
Primary microcephaly is a rare neurogenic and genetically heterogeneous disorder characterized by significant brain size reduction that results in...
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Map** the EQ-5D-5L from the Spanish national health survey functional disability scale through Bayesian networks
PurposePreference-based measures are valuable tools for evaluating therapeutic interventions and for cost-effectiveness studies. Map** procedures...
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FGF-21 and GDF-15 are increased in migraine and associated with the severity of migraine-related disability
BackgroundMigraine is a prevalent disorder with significant socioeconomic impact. The impairment of metabolic homeostasis in migraine warrants...
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Predictors of poor outcome following lumbar spinal fusion surgery: a prospective observational study to derive two clinical prediction rules using British Spine Registry data
PurposeLumbar spinal fusion surgery (LSFS) is common for lumbar degenerative disorders. The objective was to develop clinical prediction rules to...
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Over- and under-prescribing, and their association with functional disability in older patients at risk of further decline in Germany – a cross-sectional survey conducted as part of a randomised comparative effectiveness trial
BackgroundOlder patients at risk of functional decline are frequently affected by polypharmacy. This is associated with a further loss of...
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Prediction models for functional status in community dwelling older adults: a systematic review
BackgroundDisability poses a burden for older persons, and is associated with poor outcomes and high societal costs. Prediction models could...
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Clinical prediction models of rheumatoid arthritis and its complications: focus on cardiovascular disease and interstitial lung disease
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disease of unknown etiology with erosive, symmetric polyarthritis as the main clinical...
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Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
BackgroundDespite intensive research on preventing and treating vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage (aSAH),...
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The association between healthy aging index and trajectories of disability: a population-based cohort study
BackgroundHealthy aging index (HAI) could predict adverse health consequences including mortality and disability independent of age and comorbidity....
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Association of psychological factors with limb disability in patients with cervical radiculopathy: comparison with carpal tunnel syndrome
BackgroundRegarding musculoskeletal conditions, patient’s psychological distress, are shown to be associated with higher disability. Cervical...
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Early EEG-burst sharpness and 2-year disability in extremely preterm infants
BackgroundAutomated computational measures of EEG have the potential for large-scale application. We hypothesised that a predefined measure of early...
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Patient’s assessment and prediction of recovery after stroke: a roadmap for clinicians
Background and purposeIn neurorehabilitation clinical practice, assessment is usually more oriented to evaluate patient’s present status, than to...
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Early Hyperchloremia is Independently Associated with Death or Disability in Patients with Intracerebral Hemorrhage
BackgroundOn the basis of increased mortality associated with hyperchloremia among critically ill patients, we investigated the effect of occurrence...
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Identifying the neurodevelopmental and psychiatric signatures of genomic disorders associated with intellectual disability: a machine learning approach
BackgroundGenomic conditions can be associated with developmental delay, intellectual disability, autism spectrum disorder, and physical and mental...
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Co-segregation of variant NSUN2 Lue198Arg among Iranian family with intellectual disability: a case report
BackgroundIntellectual disability is characterized by impairments in adaptive behavior and cognitive functioning manifested during the developmental...
