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Emerging Treatments for Childhood Interstitial Lung Disease
Childhood interstitial lung disease (chILD) is a large and heterogeneous group of disorders characterized by diffuse lung parenchymal markings on...
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Exploring the Developmental Impact of Cystic Fibrosis on Lung Transplant Candidacy: Considerations for Adulthood
The average life expectancy for cystic fibrosis (CF) has increased over the past four decades resulting in a higher rate of adult CF patients. Adults...
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Double-lung versus heart–lung transplantation for end-stage cardiopulmonary disease: a systematic review and meta-analysis
We compared posttransplant outcomes following double-lung transplantation (DLTx) and heart–lung transplantation (HLTx), based on a search of PubMed,...
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Surgical outcomes for pediatric congenital lung malformation: 13 years’ experience
BackgroundCongenital lung malformations (CLM) are a gamut of lesions that originate throughout the embryonic period and manifest in the neonatal or...
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Childhood interstitial lung disease in Turkey: first data from the national registry
AbstractThe childhood interstitial lung diseases (chILD) Turkey registry (chILD-TR) was established in November 2021 to increase awareness of...
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Lymphatic anomalies in congenital heart disease
Congenital heart disease can lead to various lymphatic complications including traumatic leaks, lymphatic overproduction, conduction abnormalities or...
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Epithelial cell-adhesion protein cadherin 26 is dysregulated in congenital diaphragmatic hernia and congenital pulmonary airway malformation
BackgroundCongenital diaphragmatic hernia (CDH) and congenital pulmonary airway malformation (CPAM) are two inborn pathologies of the lung of unknown...
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The effect of N-acetylcysteine in patients with non-cystic fibrosis bronchiectasis (NINCFB): study protocol for a multicentre, double-blind, randomised, placebo-controlled trial
BackgroundN-acetylcysteine (NAC), which is specifically involved in airway mucus clearance and antioxidation, is recommended by the treatment...
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Retroperitoneal Bronchogenic Cyst Mimicking a Pancreatic Cystic Lesion with Extremely High Level of Intralesional Fluid CA-19.9 Antigen: Benign in Disguise
Bronchogenic cysts are congenital benign tumors resulting from abnormal budding of the primitive foregut. Usually presented on the posterior...
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Fibrosing Interstitial Lung Disease in Children: An HRCT-Based Analysis
ObjectiveTo determine high resolution CT (HRCT) patterns of pulmonary fibrosis (PF) in children; and their etiological correlates.
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Solitary multicystic lesion lung cancer: two case reports and review of the literature
BackgroundLung cancer associated with cystic airspaces, especially solitary multicystic lesion lung cancer, is a rare disease (a rare imaging...
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Lung Transplantation in India: a Brief Review, Landmarks, Indian Scenario, and our Experience
Lung transplantation is gaining widespread acceptance as the preferred therapeutic option for selected cases of end-stage lung disease in India. The...
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A comprehensive study of the rare diseases and conditions targeted by orphan drug designations and approvals over the forty years of the Orphan Drug Act
BackgroundRare diseases affect more than 30 million Americans. The passage of the Orphan Drug Act (ODA) in the United States in 1983 represented a...
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Childhood interstitial lung disease more prevalent in infancy: a practical review
Childhood interstitial lung disease (chILD) is a heterogeneous group of uncommon, mostly chronic pediatric pulmonary disorders characterized by...
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Advances for pediatricians in 2022: allergy, anesthesiology, cardiology, dermatology, endocrinology, gastroenterology, genetics, global health, infectious diseases, metabolism, neonatology, neurology, oncology, pulmonology
The last year saw intensive efforts to advance knowledge in pediatric medicine. This review highlights important publications that have been issued...
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Validation of nasal tracheal aspiration in children with lung disease
BackgroundNasal tracheal aspiration (NTA) is a frequently used diagnostic method to assess of infections in the lower airways. However, the validity...
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The genetic basis of congenital anomalies of the kidney and urinary tract
During the past decades, remarkable progress has been made in our understanding of the molecular basis of kidney diseases, as well as in the ability...
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Epidemiology of congenital diaphragmatic hernia among 24 million Chinese births: a hospital-based surveillance study
BackgroundThe prevalence of congenital diaphragmatic hernia (CDH) varies across countries, with limited information available on its epidemiology in...
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Lung infections in immunocompromised children
Pulmonary infection is the leading cause of infectious morbidity and mortality in children with immune defects. We provide a comprehensive review of...
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Neonatal interstitial lung disease in a girl with Jacobsen syndrome: a case report
BackgroundWe report a case of the neonatal interstitial lung disease pulmonary interstitial glycogenosis in a girl with Jacobsen syndrome. While...