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Dry eye signs and symptoms in patients on aromatase inhibitor therapy
PurposeThe study aimed to test whether symptomatic dry eye in aromatase inhibitor (AI) patients is associated with the clinical features of...
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Indirect signs of infravesical obstruction on voiding cystourethrography improve post-neonatal posterior urethral valves detection rate
ObjectivesTo identify the diagnostic performance of clinical and radiological signs (on voiding cystourethrography [VCUG]) to detect posterior...
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Metastatic pheochromocytoma and paraganglioma: signs and symptoms related to catecholamine secretion
BackgroundThe presence or future development of metastatic pheochromocytomas or paragangliomas (mPPGLs) can be difficult to diagnose or predict at...
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Overlap** Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
BackgroundParoxysmal sympathetic hyperactivity (PSH) occurs in a subset of patients with traumatic brain injury (TBI) and is associated with worse...
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Effect of Yu**Feng granules on clinical symptoms of stable COPD: study protocol for a multicenter, double-blind, and randomized controlled trial
BackgroundReducing current clinical symptoms and the risks of future exacerbations is the main goal of stable COPD management. Traditional Chinese...
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MR imaging signs of shoulder adhesive capsulitis: analysis of potential differentials and improved diagnostic criteria
ObjectiveTo evaluate the prevalence of shoulder adhesive capsulitis (AC) signs on MR studies of patients with various common shoulder conditions.
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COVID-19 in Female and Male Athletes: Symptoms, Clinical Findings, Outcome, and Prolonged Exercise Intolerance—A Prospective, Observational, Multicenter Cohort Study (CoSmo-S)
BackgroundAn infection with SARS-CoV-2 can lead to a variety of symptoms and complications, which can impair athletic activity.
Objective ...
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Evaluation of the signs and symptoms of pseudotumor cerebri syndrome in pediatric population
PurposePseudotumor cerebri syndrome (PTC) is characterized by increased intracranial pressure without a space-occupying lesion and a normal...
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Clinical features analysis of Kawasaki disease with abdominal symptoms as the first manifestation
To investigate the clinical characteristics of Kawasaki disease (KD) presenting with abdominal manifestation as the first manifestation. Our findings...
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Reliability of early stage symptoms/clinical findings of osteonecrosis of the jaw: Japanese Osteoporosis Intervention Trial-05 (JOINT-05)
IntroductionTo investigate the differences in the incidence rates of suspected stage 0/1 osteonecrosis of the jaw (ONJ) and incidence risk of...
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Network Analysis of the Structure of the Core Symptoms and Clinical Correlates in Comorbid Schizophrenia and Gambling Disorder
Few studies have analyzed the clinical profile of treatment-seeking patients with the comorbid presence of schizophrenia (SCZ) and gambling disorder...
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Impact of autonomic symptoms on the clinical course of Parkinson’s disease
PurposePatients with Parkinson’s disease (PD) exhibit various degrees of autonomic symptoms, which may be associated with Lewy body pathology...
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TNF-α inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China
PurposeThis study evaluated the clinical safety and efficacy of tanfanercept (HBM9036) ophthalmic solution as a novel treatment for dry eye disease...
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Symptoms and clinical features in patients affected by endolymphatic sac tumor: a systematic review and meta-analysis
PurposeMost ELST data in the literature are case studies or limited to small cohorts (< 16 patients). We evaluated the main clinical signs observed...
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Clinical impact and misdiagnosis of functional ophthalmological symptoms: a case report
BackgroundThere is a high prevalence of somatoform disorders and medically unexplained symptoms. When it comes to deciding whether a patient is able...
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Sensory signs and symptoms in women with self-reported breast cancer–related lymphedema: a case–control study close up
PurposeIt is not clear to what extent signs and symptoms other than arm swelling, including pain, altered sensory function, and body perception...
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Comparison of therapeutic effects of N-Acetylcysteine with pregabalin in improving the clinical symptoms of painful diabetic neuropathy: a randomized, double-blind clinical trial
ObjectivesPainful diabetic neuropathy (PDN) is highly prevalent and annoyingly in patients with diabetes. The aim of this study was to investigate...
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What improvements in levator ani motor function lead to improvement in stress urinary incontinence signs and symptoms in females?
Introduction and hypothesisThe objectives were to determine whether levator ani muscle (LAM) motor function is associated with female stress urinary...
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Symptoms and prevalence of common mental disorders in a heterogenous outpatient sample: an investigation of clinical characteristics and latent subgroups
BackgroundPatient-reported outcome measures (PROM) provide clinicians with information about patients’ perceptions of distress. When linked with...
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Early neurological signs in infants identified through neonatal screening for SMA: do they predict outcome?
Neonatal screening for SMA has allowed the identification of infants who may present with early clinical signs. Our aim was to establish whether the...
