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Exploring the associations between adverse childhood experiences (ACEs) and adolescent cancer risk behaviours in the ALSPAC cohort
BackgroundSome modifiable risk factors for cancer originate during adolescence. While there is evidence indicating relationships between adverse...
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Generation time-out grows up: young adults’ reports about childhood time-out use and their mental health, attachment, and emotion regulation
Time-out (TO) is a widely utilised parental discipline technique with a strong evidence-base that nonetheless has attracted controversy regarding...
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Socioeconomic position and adverse childhood experiences as risk factors for health-related behaviour change and employment adversity during the COVID-19 pandemic: insights from a prospective cohort study in the UK
BackgroundNon-pharmaceutical interventions to reduce the spread of COVID-19 may have disproportionately affected already disadvantaged populations.
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Differential Mechanisms Linking Early Childhood Threat and Social/Environmental Deprivation to Adolescent Conduct Problems
PurposeThe dimensional model of adversity and psychopathology (DMAP) posits dimensions of childhood adversity (i.e., deprivation, threat)...
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Role of Adverse Childhood Experiences in the Onset of Overweight/Obesity
Purpose of ReviewThe goal of this chapter was to summarize the literature on childhood adversity and obesity, discuss treatment implications with a...
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The social ecology of childhood and early life adversity
AbstractAn increasing prevalence of early childhood adversity has reached epidemic proportions, creating a public health crisis. Rather than focusing...
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Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences
The experience of adversity in childhood has been associated with poor health outcomes in adulthood. In search of the biological mechanisms...
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Narrative coherence of autobiographical memories in women with borderline personality disorder and associations with childhood adversity
BackgroundPeople suffering from Borderline Personality Disorder (BPD) seem to have incoherent autobiographical narratives. Tentative evidence...
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Higher exposure to childhood adversity associates with lower adult flourishing
BackgroundAdverse childhood experiences (ACEs) are prevalent and associated with negative health and social outcomes. However, our understanding of...
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Childhood Adversity and Illness Appraisals as Predictors of Health Anxiety in Emerging Adults with a Chronic Illness
Emerging adults with a chronic medical condition (CMC) are at increased risk for develo** health anxiety (HA). Adverse childhood experiences...
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Efficacy of a transdiagnostic ecological momentary intervention for improving self-esteem (SELFIE) in youth exposed to childhood adversity: study protocol for a multi-center randomized controlled trial
BackgroundTargeting low self-esteem in youth exposed to childhood adversity is a promising strategy for preventing adult mental disorder, but...
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Childhood adversities and memory function in later life: the mediating role of activity participation
BackgroundChildhood adversities may lead to decreased activity participation in later life, impacting memory health in ageing adults. Childhood...
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The role of childhood unpredictability in adult health
This research differentiated childhood unpredictability (i.e., perceptions of uncertainty or instability due to turbulent environmental changes) from...
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Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland
Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable...
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Health Care Access and Quality Among Children Exposed to Adversity: Implications for Universal Screening of Adverse Childhood Experiences
ObjectivesGiven recent advances toward universal screening for Adverse Childhood Experiences (ACEs), our objective was to investigate whether...
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Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to interpersonal violence
Early childhood and pregnancy are two sensitive periods of heightened immune plasticity, when exposure to adversity may disproportionately increase...
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Schizophrenia polygenic risk is associated with child mental health problems through early childhood adversity: evidence for a gene–environment correlation
Previous studies have shown that schizophrenia polygenic risk predicts a multitude of mental health problems in the general population. Yet it is...
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Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations
Early exposure to psychosocial adversity is among the most potent predictors of depression. Because depression commonly emerges prior to adulthood,...
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The effects of early life adversity on children’s mental health and cognitive functioning
Emerging evidence suggests that partially distinct mechanisms may underlie the association between different dimensions of early life adversity (ELA)...