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Adverse Event Profiles of Antiseizure Medications and the Impact of Coadministration on Drug Tolerability in Adults with Epilepsy
BackgroundAntiseizure medication (ASM) as monotherapy or in combination is the treatment of choice for most patients with epilepsy. Therefore,...
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Demenz und Epilepsie
Epilepsy and dementia are two diseases that peak with age. Neuropathological and epidemiological evidence suggests that the two diseases interact and...
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Fenfluramine for the treatment of status epilepticus: use in an adult with Lennox–Gastaut syndrome and literature review
BackgroundNovel treatments are needed to control refractory status epilepticus (SE). This study aimed to assess the potential effectiveness of...
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Safety and Tolerability of Adjunctive Brivaracetam in Pediatric Patients < 16 Years with Epilepsy: An Open-Label Trial
ObjectiveThis trial evaluated the short-term safety and tolerability, steady-state pharmacokinetics, and preliminary efficacy of brivaracetam oral...
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Status epilepticus in the ICU
Status epilepticus (SE) is a common medical emergency associated with significant morbidity and mortality. Management that follows published...
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Antiseizure Drugs and Movement Disorders
The relationship between antiseizure drugs and movement disorders is complex and not adequately reviewed so far. Antiseizure drugs as a treatment for...
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Synergistic effects of vagus nerve stimulation and antiseizure medication
IntroductionVagus nerve stimulation (VNS) is an effective, non-pharmacological therapy for epileptic seizures. Until now, favorable combinations of...
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Elektrotherapeutische Stellatumblockade bei einer Patientin mit komplexem regionalem Schmerzsyndrom der oberen Extremität
The case of a 51-year-old patient with complex regional pain syndrome (CRPS) of the left hand after radius distortion is reported. Anticonvulsant...
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Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis
BackgroundBrivaracetam (BRV), cenobamate (CNB), eslicarbazepine acetate (ESL), lacosamide (LCM) and perampanel (PER) are antiseizure medications...
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Pharmakotherapie der Epilepsie
In regulatory trials for the treatment of newly diagnosed focal epilepsies, levetiracetam, zonisamide, lacosamide, and eslicarbazepine were...
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Therapeutic options for patients with status epilepticus in old age—English version
Status epilepticus (SE) is a serious acute condition that requires early and targeted treatment. Especially refractory SE (RSE) as well as...
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Therapeutische Optionen für Patienten mit Status epilepticus im höheren Lebensalter
Status epilepticus (SE) is a serious acute condition that requires early and targeted treatment. Especially refractory SE (RSE) as well as...
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Impact of Antiseizure Medications on Appetite and Weight in Children
There are numerous potential factors that may affect growth in children with epilepsy, and these must be evaluated in any child with appetite and...
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Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies
The developmental and epileptic encephalopathies encompass a group of rare syndromes characterised by severe drug-resistant epilepsy with onset in...
