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Efficacy and Safety of Ivabradine in Combination with Beta-Blockers in Patients with Stable Angina Pectoris: A Systematic Review and Meta-analysis
IntroductionBeta-blockers are recommended by the European Society of Cardiology as first-line antianginal therapy for reducing heart rate (HR) and...
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Pre-operative beta-blocker therapy does not affect short-term mortality after esophageal resection for cancer
BackgroundIt has been postulated that the hyperadrenergic state caused by surgical trauma is associated with worse outcomes and that β-blockade may...
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Long-acting antimuscarinic therapy in patients with chronic obstructive pulmonary disease receiving beta-blockers
BackgroundBeta-blocker therapies for cardiovascular comorbidities are often withheld in patients with chronic obstructive pulmonary disease (COPD)...
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Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis
Aims/hypothesisRecovering functional beta cell mass is a promising approach for future diabetes therapies. The aim of the present study is to...
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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
Aims/hypothesisIncreased circulating levels of incompletely processed insulin (i.e. proinsulin) are observed clinically in type 1 and type 2...
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Beta-blockers and mechanical dyssynchrony in heart failure assessed by radionuclide ventriculography
BackgroundRadionuclide ventriculography (RNVG) can be used to quantify mechanical dyssynchrony and may be a valuable adjunct in the assessment of...
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Beta blocker use in traumatic brain injury based on the high-sensitive troponin status (BBTBBT): methodology and protocol implementation of a double-blind randomized controlled clinical trial
BackgroundBeta-adrenergic receptor blockers (BB) play an important role in the protection of organs that are susceptible for secondary injury due to...
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Beta-blockade is not associated with improved outcomes in isolated severe extracranial injury: an observational cohort study
BackgroundThere is evidence supporting the use of beta-blockade in patients with traumatic brain injury. The reduction in sympathetic drive is...
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Anesthetic implications and role of preoperative beta blockade in esophageal substitution with stomach in pediatric surgical patients
BackgroundThere is a paucity of literature on the anesthetic management of pediatric esophageal substitution using the stomach. We did a...
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Combination therapy of beta-blockers and digoxin is associated with increased risk of major adverse cardiovascular events and all-cause mortality in patients with atrial fibrillation: a report from the GLORIA–AF registry
The effect of digoxin and beta-blockers on cardiovascular outcomes and mortality remains unclear. The study aimed to determine differences in...
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Higher systolic blood pressure is specifically associated with better islet beta-cell function in T2DM patients with high glycemic level
BackgroundPatients with type 2 diabetes mellitus (T2DM) usually have higher blood viscosity attributed to high blood glucose that can decrease blood...
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Association Between Beta-Blockers and Mortality and Readmission in Older Patients with Heart Failure: an Instrumental Variable Analysis
BackgroundThe demographics of heart failure are changing. The rate of growth of the “older” heart failure population, specifically those ≥ 75, has...
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Compromised trigemino-coerulean coupling in migraine sensitization can be prevented by blocking beta-receptors in the locus coeruleus
BackgroundMigraine is a disabling neurological disorder, characterized by recurrent headaches. During migraine attacks, individuals often experience...
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Hypotension and respiratory events related to electrical cardioversion for atrial fibrillation or atrial flutter in the emergency department
IntroductionElectrical cardioversion for atrial fibrillation/atrial flutter (AF/AFL) is common in the ED. Our previous work showed that hypotension...
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Use of Non-selective Beta blockers in Decompensated Cirrhosis and ACLF
Purpose of ReviewOur understanding of beta blockers in liver cirrhosis has transformed over the last 40 years. However, questions remain over their...
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The Role of Systemic and Topical Beta-Blockers in Dermatology: A Systematic Review
IntroductionBeta-blockers are proven to be safe and cost-effective agents in treating multiple dermatological conditions, which is why they are...
