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Comparing the Analgesic Effects Between the Pre- and Post-costal Cartilage Harvest Cohorts Using Ultrasound-Guided Deep Serratus Anterior Plane Block in Children with Microtia Undergoing Auricular Reconstruction: A Randomized Clinical Trial
PurposePain following costal cartilage harvest surgery is the most common complaint of auricular reconstruction (AR). Anesthesiologists are...
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Analgesic benefits of pre-operative versus postoperative transversus abdominis plane block for laparoscopic cholecystectomy: a frequentist network meta-analysis of randomized controlled trials
BackgroundTransversus abdominis plane (TAP) block has been utilized to alleviate pain following laparoscopic cholecystectomy (LC). However, the...
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Longitudinal Study of Analgesic Use and Risk of Incident Persistent Tinnitus
BackgroundPersistent tinnitus is common, disabling, and difficult to treat. High-dose aspirin may precipitate tinnitus, but longitudinal data on...
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Rescaling pain intensity measures for meta-analyses of analgesic medicines for low back pain appears justified: an empirical examination from randomised trials
ObjectiveMeta-analyses of analgesic medicines for low back pain often rescale measures of pain intensity to use mean difference (MD) instead of...
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Comparison of analgesic efficacy of different local anesthetic volumes for erector spinae plane block in thoracotomy patients; a prospective randomized trial
BackgroundErector spinae plane block (ESPB) is a thoracic wall block that has been used frequently in recent years. It was aimed to compare the...
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Comparison of analgesic efficacy of perineural dexamethasone in rectus sheath block and intravenous dexamethasone with levobupivacaine in bilateral rectus sheath block for patients undergoing midline abdominal surgery: a randomized controlled trial
BackgroundDexamethasone is used in regional analgesia to prolong the duration of analgesia and anaesthesia. The perineural and intravenous (IV)...
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Plasma concentration, cardiorespiratory and analgesic effects of ketamine-fentanyl infusion in dogs submitted to mastectomy
BackgroundThe analgesic and cardiorespiratory effects of ketamine, fentanyl, or ketamine-fentanyl constant rate infusion (CRI) in dogs undergoing...
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Analgesic efficacy of local versus proximal nerve blocks after hallux valgus surgery: a systematic review
BackgroundHallux valgus (HV) surgery is an orthopaedic procedure that commonly causes mild to moderate postoperative pain. Effective management of...
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Investigation of the analgesic effects of rhomboid intercostal and pectoral nerve blocks in breast surgery
PurposeThe objective of this study was to examine the hypothesis that the opioid consumption of patients who receive a rhomboid intercostal block...
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Effectiveness of perioperative low-dose esketamine infusion for postoperative pain management in pediatric urological surgery: a prospective clinical trial
BackgroundPostoperative pain is common in pediatric urological surgery. The study assess the impact of perioperative intravenous infusion of low-dose...
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Early analgesic administration and headache presence 7 days post-concussion in children
ObjectiveThis study investigates whether acute treatment with ibuprofen, acetaminophen, or both is associated with resolution of headache or...
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A Two-Step, Trajectory-Focused, Analytics Approach to Attempt Prediction of Analgesic Response in Patients with Moderate-to-Severe Osteoarthritis
IntroductionWe sought to predict analgesic response to daily oral nonsteroidal anti-inflammatory drugs (NSAIDs) or subcutaneous tanezumab 2.5 mg...
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The effectiveness and safety of paediatric prehospital pain management: a systematic review
BackgroundClinically meaningful pain reduction with respect to severity and the adverse events of drugs used in prehospital pain management for...
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Usability and effectiveness of inhaled methoxyflurane for prehospital analgesia - a prospective, observational study
BackgroundPain relief in the prehospital setting is often insufficient, as the administration of potent intravenous analgesic drugs is mostly...
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Analgesic Efficacy of Gabapentin and Pregabalin in Patients Undergoing Laparoscopic Bariatric Surgeries: a Systematic Review and Meta-analysis
This meta-analysis investigated the effect of oral gabapentinoids (i.e., pregabalin and gabapentin) on analgesic consumption (i.e., primary outcome)...
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Perioperative Breast Analgesia: a Systematic Review of the Evidence for Perioperative Analgesic Medications
Purpose of ReviewBreast surgery is common and may result in significant acute as well as chronic pain. A wide range of pharmacologic interventions is...
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Analgesic Efficacy of Pectoral Nerve Blocks in Implant-Based Mammoplasty: A Systematic Review and Meta-Analysis
ObjectiveTo evaluate the analgesic effect of pectoral nerve block in implant-based mammoplasty.
MethodsEMbase, PubMed, Web of science, MEDLINE,...
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An in vivo evaluation of anti-inflammatory, analgesic and anti-pyretic activities of newly synthesized 1, 2, 4 Triazole derivatives
BackgroundIn recent years, 1, 2, 4-triazole and its derivatives have been reported to be pharmacologically significant scaffolds. They possess...
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Effectiveness of transcranial direct current stimulation in chronic pain and neurogenic claudication related to lumbar spinal stenosis
ObjectivesTranscranial direct current stimulation (tDCS) is a promising non-invasive brain stimulation technique for treating chronic pain, yet its...
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Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials
BackgroundLaparoscopic cholecystectomy is the gold standard surgical procedure for treating gallstone disease. Despite it being minimally invasive,...
