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Associations among the mutational landscape, immune microenvironment, and prognosis in Chinese patients with hepatocellular carcinoma
Recent studies suggested that the immune microenvironment and mutational landscape are associated with the response to immune-based therapy in...
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Molecular evolution in different subtypes of multifocal hepatocellular carcinoma
BackgroundMultifocal hepatocellular carcinoma (MF-HCC) accounts for > 40% of HCCs, exhibiting a poor prognosis than single primary HCCs....
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Betel Quid and Oral Phenomenon: Current Review
Purpose of ReviewBetel quid chewing (BQC) is a traditional custom of masticating and spitting out a mixture of areca nut, betel leaves, and additives...
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What effect do mycotoxins, cell wall components, enzymes and other mold components and metabolites have on our health?
The AWMF (Association of the Scientific Medical Societies) mold guideline “Medical clinical diagnostics for indoor mold exposure”—Update 2023 [
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Effects of aflatoxins on some reproductive hormones and composition of buffalo’s milk
The aim of this study was to assess the effects of feeding aflatoxins on some reproductive hormones and on the composition of buffalo milk. Forty...
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Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in the Western world. Cirrhosis remains the predominant risk...
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Updated epidemiology of gastrointestinal cancers in East Asia
Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence and one-third of cancer-related mortality. Although there...
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Key quality factors for Chinese herbal medicines entering the EU market
Chinese herbal medicines (CHMs) have unique advantages in the prevention and treatment of diseases, which are widely recognized in the world. More...
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Recent Advances in Anticancer Activity of Novel Plant Extracts and Compounds from Curcuma longa in Hepatocellular Carcinoma
PurposeAmong all forms of cancers, hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. There are several treatment options for...
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Associations of methylene tetrahydrofolate reductase (MTHFR) polymorphism with hepatocellular carcinoma in Egyptian population
Liver serves as a hub for key metabolic pathways such as folate cycle that provides one-carbon units for a network of metabolic reactions....
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The value of kidney biochemical parameters in diagnosis of acute tubular necrosis (ATN) in chickens
Acute tubular necrosis (ATN) is one of the main causes of acute renal failure of kidney origin. This state can be caused by the increase in the use...
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Gallbladder cancer
Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a very poor prognosis when diagnosed at advanced stages...
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Genomic and transcriptomic profiling of hepatocellular carcinoma reveals a rare molecular subtype
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide, occurring predominantly in patients with underlying...
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Liver cancer wars: plant-derived polyphenols strike back
Liver cancer currently represents the leading cause of cancer-related death worldwide. The majority of liver cancer arises in the context of chronic...
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Squamous Cell Carcinoma of the Middle Ear—A Common Tumor at an Uncommon Site
Squamous cell carcinoma of the middle ear is a very rare tumor. Early detection is uncommon as the tumor usually manifests as persistent ear...
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Deoxynivalenol damages the intestinal barrier and biota of the broiler chickens
BackgroundIn the livestock feed industry, feed and feed raw materials are extremely susceptible to mycotoxin contamination. Deoxynivalenol (DON) is...
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Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients
BackgroundAs a result of the lack of screening programs and the difficulty in making a proper diagnosis, the majority of hepatocellular carcinoma...