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1. Clinical trials in acute repetitive seizures and status epilepticus

   This paper reviews the clinical trials in acute repetitive seizures and in tonic-clonic status epilepticus. There are good randomised controlled...

   Simon Shorvon in Epileptic Disorders

   Article 01 June 2012

2. Pharmacotherapy of Epilepsy

   This article discusses seven newly available antiepileptic drugs (AEDs) and agents in phase III development.

   Lacosamide, licensed as an adjunctive...

   Linda J. Stephen, Martin J. Brodie in CNS Drugs

   Article 01 February 2011
   

3. Clavulanic acid does not affect convulsions in acute seizure tests in mice

   Clavulanic acid (CLAV) inhibits bacterial β-lactamases and is commonly used to aid antibiotic therapy. Prompted by the initial evidence suggestive of...

   Maciej Gasior, Katarzyna Socała, ... Piotr Wlaź in Journal of Neural Transmission

   Article Open access 03 June 2011
   

4. Seizure Management in the Setting of Hepatic Disease

   In the past 20 years, many antiepileptic drugs (AEDs) have been marketed that are not significantly metabolized by the liver, but some patients still...

   Jane G. Boggs in Current Treatment Options in Neurology

   Article 03 May 2011

5. Piracetam and Piracetam-Like Drugs

   There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since the last meta-analysis of the clinical efficacy of...

   Andrei G. Malykh, M. Reza Sadaie in Drugs

   Article 01 February 2010
   

6. Levetiracetam for levodopa-induced dyskinesia in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial

   The aim of this study was to assess the efficacy, safety and tolerability of the antiepileptic compound levetiracetam (LEV) for the treatment of...

   Martin Wolz, Matthias Löhle, ... Alexander Storch in Journal of Neural Transmission

   Article 29 August 2010
   

7. The evolution of antiepileptic drug development and regulation

   The early years of antiepileptic drug development were characterised by observation and serendipity, rather than a rational, targeted approach to...

   Alexis Arzimanoglou, Elinor Ben-Menachem, ... Miranda Harrison in Epileptic Disorders

   Article 01 March 2010

8. Proceedings of the 2012 World Molecular Imaging Congress, Dublin, Ireland, September 5-8, 2012

   in Molecular Imaging and Biology

   Article 08 November 2012

9. Pharmacological Management of Epilepsy

   There is still a need for new antiepileptic drugs (AEDs) as the clinical efficacy, tolerability, toxicity or pharmacokinetic properties of existing...

   Cecilie Johannessen Landmark, Svein I. Johannessen in Drugs

   Article 01 October 2008
   

10. New molecular targets for antiepileptic drugs: α₂δ, SV2A, and K_v7/KCNQ/M potassium channels

    Many currently prescribed antiepileptic drugs (AEDs) act via voltage-gated sodium channels, through effects on γ-aminobutyric acid-mediated...

    Michael A. Rogawski, Carl W. Bazil in Current Neurology and Neuroscience Reports

    Article 01 July 2008

11. Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus

    In the present study, we evaluated the anti-seizure and anti-myoclonic activity of levetiracetam and brivaracetam in an established rat model of...

    K.-K. Tai, D. D. Truong in Journal of Neural Transmission

    Article 10 August 2007

12. Myoclonus

    Myoclonus is a hyperkinetic movement disorder characterized by quick, involuntary jerks. It encompasses a vast range of etiologies and widespread...

    Victoria C. Chang, Steven J. Frucht in Current Treatment Options in Neurology

    Article 16 May 2008

13. Antiepileptic Drugs in Non-Epilepsy Disorders

    Antiepileptic drugs (AEDs) are used extensively to treat multiple non-epilepsy disorders, both in neurology and psychiatry. This article provides a...

    Cecilie Johannessen Landmark in CNS Drugs

    Article 01 January 2008