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CNS Adverse Events Associated with Antiepileptic Drugs
A variety of newer antiepileptic drugs (AEDs) are now available for treating patients with epilepsy in addition to the ‘conventional’ drugs that have...
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Use of Second-Generation Antiepileptic Drugs in the Pediatric Population
Epilepsy is common in the pediatric population. Nine second-generation antiepileptic drugs have been approved in the US for use in epilepsy over the...
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Antiepileptic Drugs in Non-Epilepsy Disorders
Antiepileptic drugs (AEDs) are used extensively to treat multiple non-epilepsy disorders, both in neurology and psychiatry. This article provides a...
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Brivaracetam is superior to levetiracetam in a rat model of post-hypoxic myoclonus
In the present study, we evaluated the anti-seizure and anti-myoclonic activity of levetiracetam and brivaracetam in an established rat model of...
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Acute and prophylactic treatments for migraine: present and future
Herein I will present general principles of acute-care and preventive therapy of migraine, both in the present and the future. Details of currently...
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Retrospective analysis of the efficacy and tolerability of levetiracetam in patients with metastatic brain tumors
Seizures are a common complication of metastatic brain tumors (MBT), affecting approximately 27–50% of all patients during the course of their...
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Levetiracetam for the treatment of hot flashes: a phase II study
Goals of workThe objectives of this pilot trial were to assess the potential efficacy and safety of levetiracetam for the treatment of hot flashes, a...
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IV levetiracetam in the management of non-convulsive status epilepticus
IntroductionStatus epilepticus (SE) is a medical emergency requiring prompt treatment to try to limit mortality and improve outcome. So far, newer...
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Tuberous sclerosis successfully treated with levetiracetam monotherapy: 18 months of follow-up
CaseWe present the case of a boy with tuberous sclerosis who was referred for evaluation and treatment of his intractable epileptic seizures, having...
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Levetiracetam in three cases of progressive myoclonus epilepsy
We present three unrelated cases of genetically confirmed progressive myoclonic epilepsy of the Unverricht–Lundborg type who were treated with...
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Etiology and management of refractory epilepsies
The epilepsies are an important, common and diverse group of symptom complexes characterized by recurrent spontaneous seizures. Although many...
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Future aspects of botulinum neurotoxins
The future of botulinum neurotoxin (BoNT) development is expected to proceed along two lines: the development of novel indications and the...
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Potential of Levetiracetam in
Levetiracetam is a newer antiepileptic agent that was first approved by the US FDA in 1999 as an adjunctive therapy for the treatment of refractory...
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The future of acute care and prevention in headache
Migraine is a chronic neurological disease with heterogeneous characteristics resulting in a range of symptom profiles, burden and disability. It...
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Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage
ObjectivesProphylactic treatment with antiepileptic drugs is common practice following subarchnoid hemorrhage (SAH) and traumatic brain injury....
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Pharmacokinetic Variability of Newer Antiepileptic Drugs
A new generation of antiepileptic drugs (AEDs) has reached the market in recent years with ten new compounds: felbamate, gabapentin, lamotrigine,...
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Levetiracetam for cerebellar tremor in multiple sclerosis
PurposeDisabling tremor is frequent in multiple sclerosis (MS) and its treatment remains challenging. We conducted an open–label trial to evaluate...