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Adverse Effects of Meditation: Autonomic Nervous System Activation and Individual Nauseous Responses During Samadhi Meditation in the Czech Republic
Buddhist meditation practices, including Samadhi meditation, which forms the basis for mindfulness practice, are broadly promoted as pathways to...
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Effects of Adverse Childhood Experiences and Chronic Health Conditions on Current Depression
This study investigated the ability of three adverse childhood experience (ACE) types (household dysfunction, emotional/physical abuse, and sexual...
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Sex Differences Between Female and Male Individuals in Antipsychotic Efficacy and Adverse Effects in the Treatment of Schizophrenia
Background and ObjectiveAntipsychotics are core treatments for people living with psychotic disorders. Understanding individualised factors that...
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Effect of important modifiers on harmful effects in evidence synthesis practice of adverse events were insufficiently investigated: an empirical investigation
BackgroundSafety is important in the assessment of health interventions, while the results of adverse events are often susceptive to potential effect...
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Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology
Ample evidence suggests that acute stress can worsen symptom severity in Tourette syndrome (TS); however, the neurobiological underpinnings of this...
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A Pragmatic Approach to Managing Long-Term Adverse Effects in Chronic Myeloid Leukemia Treatment
Purpose of ReviewLong-term outcomes have significantly improved with treatment of chronic myeloid leukemia. With proper treatment, most patients will...
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Effects of a special continuous quality improvement in nursing on the management of adverse care events: a retrospective study
ObjectiveTo explore the application effect of the direct reporting system of adverse nursing events and special continuous nursing quality...
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Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study
IntroductionThe management of pain following a burn is extremely complex because of the multifactorial nature of burn pain (nociceptive and...
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Adverse reactions and effects on renal function of COVID-19 vaccines in patients with IgA nephropathy
BackgroundAlthough vaccination has been reported to reduce the morbidity and severity of COVID-19 infection in patients with kidney disease, gross...
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Comparison of the efficacy and adverse effects of unilateral or bilateral botulinum toxin injections for adductor spasmodic dysphonia: a systematic review and meta-analysis
PurposeThis study aims to aggregate and analyze existing clinical evidence to compare the efficacy and adverse effects of unilateral or bilateral...
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Psychological adverse effects of COVID-19 pandemic on health service providers: an online survey
BackgroundIn the current situation of the COVID-19 pandemic, health service providers (HCPs) suffered from mental health consequences such as...
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Triple network model of brain connectivity changes related to adverse mood effects in an oral contraceptive placebo-controlled trial
Combined oral contraceptives (COC) are among the most commonly used contraceptive methods worldwide, and mood side effects are the major reason for...
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An explorative analysis of pharmacovigilance data of oxytocin and its analogue carbetocin, with a focus on haemodynamic adverse effects
BackgroundOxytocin and its analogue carbetocin are uterotonics whose prophylactic use is recommended to prevent postpartum haemorrhage, which is one...
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Effects of prebiotic supplement on gut microbiota, drug bioavailability, and adverse effects in patients with colorectal cancer at different primary tumor locations receiving chemotherapy: study protocol for a randomized clinical trial
BackgroundThe prevalence of colorectal cancer (CRC) worldwide is a huge challenge to human health. Primary tumor locations found to impact prognosis...
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Adverse COVID-19 experiences and health-related quality of life in cancer survivors: indirect effects of COVID-19-related depression and financial burden
BackgroundCancer survivors are at greater risk for poor health outcomes due to COVID-19. However, the pandemic's impact on patients’ health-related...
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Comparative study on regression time of block and adverse effects of nalbuphine and fentanyl as an adjuvant to intrathecal bupivacaine: a prospective randomized double-blind study
BackgroundThe study was done to observe the effectiveness of nalbuphine as an adjuvant to intrathecal bupivacaine heavy, and hence, it was compared...
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Integrated dose–response metabolomics with therapeutic effects and adverse reactions may demystify the dosage of traditional Chinese medicine
BackgroundTraditional Chinese medicine (TCM) has been used to treat various diseases for thousands of years. However, the uncertainty of dosage as...
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Management of Pharmacologic Adverse Effects in Advanced Liver Disease
As a consequence of the altered hepatic architecture in advanced liver disease, drug metabolism is modified by changes in pharmacokinetic and...