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Changes in decision-making process for life-sustaining treatment in patients with advanced cancer after the life-sustaining treatment decisions-making act
BackgroundCancer is a leading cause of death in Korea. To protect the autonomy and dignity of terminally ill patients, the Life-Sustaining Treatment...
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Physicians’ attitudes and experiences about withholding/withdrawing life-sustaining treatments in pediatrics: a systematic review of quantitative evidence
BackgroundOne of the most important and ethically challenging decisions made for children with life-limiting conditions is withholding/withdrawing...
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Life-sustaining treatment decisions in pediatric intensive care: an Italian survey on ethical concerns
ObjectivesTo investigate how life-sustaining treatment (LST) decisions are made and identify problematic ethical concerns confronted by physicians...
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End of life care in a level IV outborn neonatal intensive care unit
ObjectiveDescribe care surrounding the end of life (EOL) in the neonatal intensive care unit (NICU).
Study designRetrospective chart review of 208...
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Improving quality of withdrawal of life-sustaining measures in organ donation: a framework and implementation toolkit
BackgroundDonation after circulatory determination of death (DCD) is responsible for the largest increase in deceased donation over the past decade....
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Withdrawal of mechanical ventilation in amyotrophic lateral sclerosis patients: a multicenter Italian survey
BackgroundLaw 219/2017 was approved in Italy in December 2017, after a years-long debate on the autonomy of healthcare choices. This Law, for the...
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Clinical outcomes and end-of-life treatment in 596 patients with isolated traumatic brain injury: a retrospective comparison of two Dutch level-I trauma centers
PurposeWith an increasingly older population and rise in incidence of traumatic brain injury (TBI), end-of-life decisions have become frequent. This...
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Physician decision-making process about withholding/withdrawing life-sustaining treatments in paediatric patients: a systematic review of qualitative evidence
BackgroundWith paediatric patients, deciding whether to withhold/withdraw life-sustaining treatments (LST) at the end of life is difficult and...
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Circumstances surrounding end of life in a Swiss pediatric intensive care unit
PurposeTo describe the modes of death (MOD), the elements related to the decision to forgo life-sustaining treatments (LST) as well as the medical...
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Balancing Patient and Societal Interests in Decisions About Potentially Life-Sustaining Treatment
BackgroundThis paper investigates the content of Australian policies that address withholding or withdrawing life-sustaining treatment to analyse the...
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Ethical Issues around Death and Withdrawal of Life Support in Neonatal Intensive Care
Amongst all the traumatic experiences in a human life, death of child is considered the most painful, and has profound and lasting impact on the life...
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Psychological Determinants of Physician Variation in End-of-Life Treatment Intensity: A Systematic Review and Meta-Synthesis
BackgroundPhysicians treating similar patients in similar care-delivery contexts vary in the intensity of life-extending care provided to their...
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Mechanisms underlying the long-term and withdrawal effects of denosumab therapy on bone
Denosumab, a human monoclonal antibody against receptor activator of nuclear factor-κB ligand (RANKL), is a potent inhibitor of osteoclast...
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Parameters affecting prognosis after hemodialysis withdrawal: experience from a single center
IntroductionWithdrawal from maintenance hemodialysis is unavoidable in some patients due to their poor general condition; however, their survival...
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Impact of advance directives on the variability between intensivists in the decisions to forgo life-sustaining treatment
BackgroundThere is wide variability between intensivists in the decisions to forgo life-sustaining treatment (DFLST). Advance directives (ADs) allow...
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Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill
BackgroundLimitations of life-sustaining interventions in intensive care units (ICUs) exhibit substantial changes over time, and large, contemporary...
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End-of-life practices in 11 German intensive care units
BackgroundEnd-of-life care is common in German intensive care units (ICUs) but little is known about daily practice.
ObjectivesTo study the practice...
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The impact of religion on changes in end-of-life practices in European intensive care units: a comparative analysis over 16 years
PurposeReligious beliefs affect end-of-life practices in intensive care units (ICUs). Changes over time in end-of-life practices were not...
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The Effects of Introducing a Harm Threshold for Medical Treatment Decisions for Children in the Courts of England & Wales: An (Inter)National Case Law Analysis
The case of Charlie Gard sparked an ongoing public and academic debate whether in court decisions about medical treatment for children in England &...