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Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3
PurposeThe role of temozolomide chemotherapy alone in isocitrate dehydrogenase (IDH)-mutant astrocytomas has not been conclusively determined....
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Cancer outpatients during the COVID-19 pandemic: what Oncoral has to teach us about medical drug use and the perception of telemedicine
PurposeThe COVID-19 pandemic has disrupted healthcare access and telemedicine has been widely deployed. The aim of this study is to assess the impact...
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The effect of bethanechol on tracheobronchomalacia in preterm infants with bronchopulmonary dysplasia: a retrospective cohort study
ObjectiveBethanechol has demonstrated improvement in trachealis tone in animal models, but no trials have studied efficacy in infants. This study...
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Pharmacogenetic activation of parvalbumin interneurons in the prefrontal cortex rescues cognitive deficits induced by adolescent MK801 administration
The cognitive symptoms of schizophrenia (SZ) present a significant clinical burden. They are treatment resistant and are the primary predictor of...
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Within-subject effects of standardized prosthetic socket modifications on physical function and patient-reported outcomes
BackgroundAmong the challenges of living with lower limb loss is the increased risk of long-term health problems that can be either attributed...
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Prognostic value of immune-related lncRNA pairs in patients with bladder cancer
BackgroundThe characteristics of immune-related long non-coding ribonucleic acids (ir-lncRNAs), regardless of their specific levels, have important...
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Comparison of Patient-Reported and Caregiver-Reported Swallowing-Related Quality of Life in Parkinson’s Disease
This pilot study explored agreement on swallowing-related quality-of-life scores reported by individuals with Parkinson’s disease (PD) and their...
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Hospital-Initiated Smoking Cessation Among Patients Admitted with Behavioral Health Conditions
BackgroundSmoking rates among people living with behavioral health conditions (BHC) range from 30 to 65% and are 2–4 times higher than rates found in...
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Dexamethasone versus methylprednisolone for multiple organ dysfunction in COVID-19 critically ill patients: a multicenter propensity score matching study
BackgroundDexamethasone usually recommended for patients with severe coronavirus disease 2019 (COVID-19) to reduce short-term mortality. However, it...
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Agreement between proxy- and self-report scores on PROMIS health-related quality of life domains in pediatric burn survivors: a National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System Study
PurposeTo examine agreement between pediatric burn survivor self- and caregiver proxy-report on multiple PROMIS domains and examine factors...
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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers
Immune checkpoint inhibitors (ICI) are highly effective in specific cancers where canonical markers of antitumor immunity are used for patient...
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Microbial signatures in amniotic fluid at preterm birth and association with bronchopulmonary dysplasia
BackgroundMicrobiome dysbiosis can have long-lasting effects on our health and induce the development of various diseases. Bronchopulmonary dysplasia...
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Phonological awareness training and phonological therapy approaches for specific language impairment children with speech sound disorders: a comparative outcome study
PurposeChildren with specific language impairment (SLI) might present with speech sound disorder (SSD) and phonological awareness (PA) deficits which...
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Comparison of automated segmentation techniques for magnetic resonance images of the prostate
BackgroundContouring of anatomical regions is a crucial step in the medical workflow and is both time-consuming and prone to intra- and...
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Deep learning based on carotid transverse B-mode scan videos for the diagnosis of carotid plaque: a prospective multicenter study
ObjectivesAccurate detection of carotid plaque using ultrasound (US) is essential for preventing stroke. However, the diagnostic performance of...
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Nudging Online Gamblers to Withdraw Money: The Impact of Personalized Messages on Money Withdrawal Among a Sample of Real-World Online Casino Players
A number of scholars have argued that online gambling can be more problematic than land-based gambling. Motivating gamblers to withdraw money from...
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Pain as bad as you can imagine or extremely severe pain? A randomized controlled trial comparing two pain scale anchors
BackgroundA common method of pain assessment is the numerical rating scale, where patients are asked to rate their pain on a scale from 0 to 10,...
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A superior approach? The role of robotic sleeve gastrectomy in patients with super super obesity using the 2019–2022 MBSAQIP database
BackgroundLaparoscopic sleeve gastrectomy (LSG) in patients with BMI ≥ 60 presents technical challenges, that might be overcome by robotic surgery,...
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Post-reconstruction enhancement of [18F]FDG PET images with a convolutional neural network
BackgroundThe aim of the study was to develop and test an artificial intelligence (AI)-based method to improve the quality of [ 18 F]fluorodeoxyglucose...
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Explaining the effect on food selection of altering availability: two experimental studies on the role of relative preferences
BackgroundIncreasing the availability of healthier or plant-based foods increases their selection. The current studies aimed to examine the extent to...
