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Effect of pediatric ventilation weaning technique on work of breathing
BackgroundVentilator liberation is one of the most challenging aspects in patients with respiratory failure. Most patients are weaned through a...
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Accuracy of respiratory muscle assessments to predict weaning outcomes: a systematic review and comparative meta-analysis
BackgroundSeveral bedside assessments are used to evaluate respiratory muscle function and to predict weaning from mechanical ventilation in patients...
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Modifiable risk factors for ventilator associated diaphragmatic dysfunction: a multicenter observational study
BackgroundDiaphragmatic dysfunction is known to be associated with difficulties weaning from invasive mechanical ventilation and is related to worse...
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Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort
BackgroundNon-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP), a nosocomial pneumonia that is not related to invasive mechanical ventilation...
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Sedation Weaning in a Patient with a Substance Abuse and Psychiatric History
BackgroundAchieving therapeutic doses of sedation and analgesia are necessary for the safety and comfort of mechanically ventilated patients....
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Fundamentals of weaning veno-arterial and veno-venous extracorporeal membrane oxygenation
Recent advances in veno-arterial (VA) and veno-venous (VV) extracorporeal membrane oxygenation (ECMO) technology and management have enabled us to...
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A comparison of two weaning strategies for non-invasive ventilation in chronic obstructive pulmonary disease patients with acute respiratory failure
IntroductionNon-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with...
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Weaning and extubation failure in myasthenic crisis: a multicenter analysis
Myasthenic crisis (MC) requiring mechanical ventilation is a serious complication of myasthenia gravis (MG). Here we analyze the frequency and risk...
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Ventilator-associated pneumonia in neurocritically ill patients: insights from the ENIO international prospective observational study
BackgroundAcute brain injured (ABI) patients are at high risk of develo** ventilator-associated pneumonia (VAP). However, incidence, risk factors...
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Pressure support and positive end-expiratory pressure versus T-piece during spontaneous breathing trial in difficult weaning from mechanical ventilation: study protocol for the SBT-ICU study
BackgroundSpontaneous breathing trials are performed in critically ill intubated patients in order to assess readiness to be weaned from mechanical...
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Diagnostic accuracy of lung ultrasound in detecting weaning-induced pulmonary edema
BackgroundWeaning-induced pulmonary edema (WIPO) is one of the commonest causes of weaning failure in critical care. As ultrasound machine is an easy...
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Automated characterization of patient–ventilator interaction using surface electromyography
BackgroundCharacterizing patient–ventilator interaction in critically ill patients is time-consuming and requires trained staff to evaluate the...
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Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
BackgroundPatients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring mechanical ventilation suffer from a...
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Diaphragmatic ultrasonography-based rapid shallow breathing index for predicting weaning outcome during a pressure support ventilation spontaneous breathing trial
BackgroundThe optimum timing to wean is crucial to avoid negative outcomes for mechanically ventilated patients. The rapid shallow breathing index...
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Efficacy of late postnatal dexamethasone on weaning from invasive mechanical ventilation in extreme premature infants
ObjectiveTo evaluate the short-term respiratory effects of PND in a cohort of ventilator-dependent premature infants.
Study designClinical data from...
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A rare case of a patient with cystinosis and COVID-19 pneumonia with difficult weaning from mechanical ventilation: the “pocus force”
Here, we describe the case of a 39-year-old woman with cystinosis who already suffered from an extra parenchymal pattern of restrictive lung disease...
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Recurrent ventilator-associated pneumonia in severe Covid-19 ARDS patients requiring ECMO support
ObjectiveTo describe ventilator-associated pneumonia (VAP) recurrence in COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO)...
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Ventilator-induced diaphragmatic dysfunction in extremely preterm infants: a pilot ultrasound study
To investigate the development of diaphragmatic dysfunction in ventilated extremely preterm infants (EPI) using diaphragm ultrasound (DU). EPI of...
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Effects of extracorporeal CO2 removal on gas exchange and ventilator settings: a systematic review and meta-analysis
PurposeA systematic review and meta-analysis to evaluate the impact of extracorporeal carbon dioxide removal (ECCO 2 R) on gas exchange and...
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Effect of high-flow oxygen versus T-piece ventilation strategies during spontaneous breathing trials on weaning failure among patients receiving mechanical ventilation: a randomized controlled trial
BackgroundA spontaneous breathing trial (SBT) is used to determine whether patients are ready for extubation, but the best method for choosing the...
