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Rho-Kinase Inhibitors as Emerging Targets for Glaucoma Therapy
Glaucoma, the leading cause of irreversible blindness worldwide, is a chronic and progressive optic neuropathy characterized by damage to the optic...
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A Cost-Utility Analysis of Trabecular Bypass Devices Versus Usual Care for Patients With Open-Angle Glaucoma
ObjectiveThe aim of this study was to determine whether insertion of a trabecular bypass device (TBD) is a cost-effective intervention for the...
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iStent inject Trabecular Micro-Bypass with or Without Cataract Surgery Yields Sustained 5-Year Glaucoma Control
IntroductionThis study evaluated the 5-year effectiveness and safety of iStent inject ® trabecular micro-bypass with or without cataract surgery...
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Surgical Outcomes of Combined 2nd-Generation Trabecular Microbypass (iStent Inject) and Cataract Surgery for the Treatment of Primary Open-Angle Glaucoma in the Saudi Population
IntroductionTo investigate the 24-month efficacy and safety of iStent inject trabecular microbypass system implantation combined with...
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Long-term outcomes of two first-generation trabecular micro-bypass stents (iStent) with phacoemulsification in primary open-angle glaucoma: eight-year results
BackgroundThe short- and medium-term outcomes of iStent have been extensively studied; however, only few studies have investigated its long-term...
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Dose-dependent effects of netarsudil, a Rho-kinase inhibitor, on the distal outflow tract
PurposeTo characterize the effects of netarsudil on the aqueous humor outflow tract distal to the trabecular meshwork (TM). We hypothesized that...
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Tissue-engineered anterior segment eye cultures demonstrate hallmarks of conventional organ culture
BackgroundGlaucoma is a blinding disease largely caused by dysregulation of outflow through the trabecular meshwork (TM), resulting in elevated...
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Outcomes of phacoemulsification and endoscopic cyclophotocoagulation performed with dual blade ab interno trabeculectomy or trabecular micro-bypass stent insertion
Background/ObjectiveTo report the initial outcomes of phacoemulsification, endoscopic cyclophotocoagulation, and dual blade ab interno trabeculectomy...
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Favorable effect of ripasudil use on surgical outcomes of microhook ab interno trabeculotomy
PurposeWe have previously demonstrated that prolonged use of glaucoma medications was associated with a poor surgical outcome of ab interno ...
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Minimally Invasive Glaucoma Surgery: Where We Are, and What the Future Holds
Purpose of ReviewMinimally invasive glaucoma surgery, or MIGS, has revolutionized the glaucoma surgical space in the past 15 years. The high safety...
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Aqueous outflow imaging techniques and what they tell us about intraocular pressure regulation
Recent advances in the medical and surgical management of open-angle glaucoma have increased the number of treatment options available. Several new...
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New Concepts in Steroid Glaucoma
Purpose of ReviewIn this article, we discuss the pathophysiology underlying intraocular pressure elevation associated with corticosteroid use as well...
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Update on Factors Contributing to Traumatic Glaucoma Following Ocular Contusion and Globe Perforation
Purpose of ReviewThis paper focuses on potential factors that can contribute to secondary traumatic glaucoma (TG) following mechanical globe injury.
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New Devices in Glaucoma
Glaucoma remains a leading cause of blindness globally. Minimally invasive treatment techniques are rapidly expanding the availability of therapeutic...
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Cost-utility analysis of trabecular micro-bypass stents (TBS) in patients with mild-to-moderate open-angle Glaucoma in Italy
BackgroundGlaucoma is a disease characterized by progressive damage of the optic nerve. Several therapeutic options are available to lower...
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Comparison of a second-generation trabecular bypass (iStent inject) to ab interno trabeculectomy (Trabectome) by exact matching
PurposeTo achieve a highly balanced comparison of trabecular bypass stenting (IS2, iStent inject) with ab interno trabeculectomy (T, Trabectome) by...
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Quantitative metrics of the LV trabeculated layer by cardiac CT and cardiac MRI in patients with suspected noncompaction cardiomyopathy
ObjectivesTo compare cardiac computed tomography (CCT) and cardiac magnetic resonance (CMR) for the quantitative assessment of the left ventricular...
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The association between corneal hysteresis and surgical outcomes from trabecular meshwork microinvasive glaucoma surgery
PurposeTo assess whether an association exists between pretreatment corneal hysteresis (CH) and the magnitude of intraocular pressure (IOP) and...
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iStent inject trabecular microbypass stent implantation with cataract extraction in open-angle glaucoma: early clinical experience
BackgroundRetrospective, consecutive case series to evaluate the implantation of two second-generation trabecular microbypass stents in combination...
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Evaluation of biometric indicators of anterior segment parameters after ICL implantation by swept-source optical coherence tomography
BackgroundTo evaluate anterior segment structural alterations after implantable collamer lens (ICL) implantation in myopic patients using...
