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Altered interhemispheric functional homotopy and connectivity in temporal lobe epilepsy based on fMRI and multivariate pattern analysis
PurposeThis study aimed to investigate how the functional homotopy and further functional connectivity (FC) of whole brain changed in temporal lobe...
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A study of brain functional network and alertness changes in temporal lobe epilepsy with and without focal to bilateral tonic–clonic seizures
BackgroundTemporal lobe epilepsy (TLE) is commonly refractory. Epilepsy surgery is an effective treatment strategy for refractory epilepsy, but...
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Temporal frequency dependence of the polarity inversion between upper and lower visual field in the pattern-onset steady-state visual evoked potential
PurposeAccording to the cruciform model, the upper and lower halves of the visual field representation in the primary visual cortex are located...
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18F-FDG-PET glucose hypometabolism pattern in patients with epileptogenic hypothalamic hamartoma
Epileptogenic hypothalamic hamartoma is characterized by intractable gelastic seizures. A systematic analysis of the overall brain metabolic pattern...
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Selective effects of acute and chronic stress on slow and alpha-theta cortical functional connectivity and reversal with subanesthetic ketamine
Anxious, depressive, traumatic, and other stress-related disorders are associated with large scale brain network functional connectivity changes, yet...
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A PET imaging study of the brain changes of glucose metabolism in patients with temporal lobe epilepsy and depressive disorder
BackgroundThis study aims to compare the difference of the brain changes of glucose metabolism between temporal lobe epilepsy patients (TLE) with...
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Endoscopic endonasal approach to the mesial temporal lobe: anatomical study and clinical considerations for a selective amygdalohippocampectomy
BackgroundSelective amygdalohippocampectomy (AH) is a surgical option for patients with medically intractable seizures from mesial temporal lobe...
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Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias
Reactive astrogliosis accompanies the two neuropathological hallmarks of Alzheimer’s disease (AD)—Aβ plaques and neurofibrillary tangles—and...
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Relationship between amyloid and tau levels and its impact on tau spreading
PurposePrevious studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, the Aβ levels...
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Electrophysiological Mechanisms of Memory Consolidation in Human Non-rapid Eye Movement Sleep
Purpose of ReviewPioneering work in rodents has shown that the reactivation of recently acquired memories during sleep is a key mechanism underlying...
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UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice
The effects of context on the subjective experience of serotonergic psychedelics have not been fully examined in human neuroimaging studies, partly...
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Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis
BackgroundTemporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) is a surgically treatable epileptic syndrome. While the core of...
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Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer’s disease
Alzheimer’s disease neuropathologic change (ADNC) is clinically heterogenous and can present with a classic multidomain amnestic syndrome or focal...
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Adding the Topographical Information from Tau-PET to the A/T/(N) Framework: Steps Towards Staging AD in Vivo
Biomarkers have revolutionized the study and clinical diagnosis of Alzheimer’s disease (AD). While amyloid-β accumulation begins decades before the...
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Chronic traumatic encephalopathy (CTE)—features and forensic considerations
Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition, in which the only known cause is exposure to repeated episodes of blunt head...
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Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer’s disease reveals distinct sequential responses to Aβ and tau
Human microglia are critically involved in Alzheimer’s disease (AD) progression, as shown by genetic and molecular studies. However, their role in...
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A longitudinal rat model for assessing postoperative recovery and bone healing following tibial osteotomy and plate fixation
BackgroundRodent models are commonly employed to validate preclinical disease models through the evaluation of postoperative behavior and allodynia....
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Convergent and divergent genes expression profiles associated with brain-wide functional connectome dysfunction in deficit and non-deficit schizophrenia
Deficit schizophrenia (DS) is a subtype of schizophrenia characterized by the primary and persistent negative symptoms. Previous studies have...
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A multimodal clinical diagnostic approach using MRI and 18F-FDG-PET for antemortem diagnosis of TDP-43 in cases with low–intermediate Alzheimer’s disease neuropathologic changes and primary age-related tauopathy
ObjectiveTo evaluate the utility of clinical assessment scales for MRI and 18 F-FDG-PET as potential in vivo predictive diagnostic tools for TAR...
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Tentorial peeling during combined petrosal approach: a cadaveric dissection
BackgroundThe combined petrosal approach is an excellent method to access the petroclival region but has the inherent risk of injury to the temporal...
