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Etanercept as a TNF-alpha inhibitor depresses experimental retinal neovascularization
PurposeThe formation of retinal neovascularization (RNV) is the primary pathological process underlying retinopathy of prematurity (ROP). Previous...
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To evaluate the relationship of obstructive sleep apnea with chronic periodontitis and its association with coronary artery disease by assessing serum tumor necrosis factor-α
The periodontal tissue initiates an immune-inflammatory response against bacteria and their products at the site of periodontal infection, and...
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The influence of selected microRNAs on the expression profile of genes and proteins related to the tumor necrosis factor-alpha signaling pathways in endometrioid endometrial cancer
PurposeTumor necrosis factor exerts many adverse biological effects, from cell proliferation to cell death. Accurate diagnosis and treatment are...
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Joint Detection of Serum Vitamin D, Body Mass Index, and Tumor Necrosis Factor Alpha for the Diagnosis of Crohn’s Disease
ObjectiveVitamin D (VD) deficiency was reported to contribute to the progression of Crohn’s disease (CD) and affect the prognosis of CD patients....
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Serum and urinary levels of tumor necrosis factor-alpha and interferon-gamma in diabetic nephropathy patients: a systematic review
ObjectiveIn this systematic review, we determined the association of selected inflammatory cytokines in blood and urine with diabetic nephropathy...
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Analysis of related factors of portal vein thrombosis in liver cirrhosis
Background and aimsTo investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and...
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Correlation Between Synovial Fluid Levels of Matrix Metalloproteinase’s (MMP-1, MMP-3, and MMP-9) and TNF-α with the Severity of Osteoarthritis Knee in Rural Indian Population
BackgroundIn India, 22% to 39% of the ageing population suffers from degenerative knee osteoarthritis (OA), making it the most prevalent joint...
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Decreased Risk of Preeclampsia in Women with Inflammatory Bowel Disease on Anti-Tumor Necrosis Factor Therapy
BackgroundEvidence suggests that upregulation of tumor necrosis factor-alpha (TNF-α) plays a role in immune dysregulation in both preeclampsia and...
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Effects of low-carbohydrate diets, with and without caloric restriction, on inflammatory markers in adults: a systematic review and meta-analysis of randomized clinical trials
Low-carbohydrate diets (LCDs) have gained interest due to their favorable effects on health outcomes, such as inflammation. However, further research...
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Secoemestrin C Ameliorates Psoriasis-like Skin Inflammation in Mice by Suppressing the TNF-α/NF-κB Signaling Pathway
ObjectiveSecoemestrin C (SC), an epitetrathiodioxopiperazine isolated from Aspergillus nidulans , has been previously reported to have...
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A novel CD47-blocking peptide fused to pro-apoptotic KLA repeat inhibits lung cancer growth in mice
CD47 is highly expressed in many tumor tissues and induces immune evasion by interaction with SIRP-alpha (signal regulatory protein-alpha) expressed...
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The relationship between self-perceived fatigue, muscle endurance, and circulating markers of inflammation in participants of the Copenhagen aging and Midlife Biobank (CAMB)
BackgroundFatigue, low muscle endurance, muscle weakness and low-grade inflammation are strongly related to frailty at higher age. When signs of...
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Role of the cAMP-PKA-NF-κB pathway in Mucin1 over-expression in A549 cells during Respiratory syncytial virus infection
Respiratory syncytial virus (RSV) is the most common pathogen associated with acute lower respiratory tract infections in infants and young children...
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Aqueous humor cytokine levels are associated with the severity of visual field defects in patients with primary open-angle glaucoma
BackgroundTo evaluate the aqueous humor (AH) levels of cytokines in primary open-angle glaucoma (POAG) patients and cataract patients.
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Anti-tumor necrosis factor-alpha treatment in pediatric patients with pars planitis: a single-center experience from Turkey
AimTo evaluate the effectiveness and safety of anti-tumor necrosis factor-alpha (anti-TNF-alpha) treatment (Adalimumab [ADA]) combined with...
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Colonic TRPV4 overexpression is related to constipation severity
BackgroundChronic constipation is prevalent and involves both colon sensitivity and various changes in intestinal bacteria, particularly...
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Daily phytate intake increases adiponectin levels among patients with diabetes type 2: a randomized crossover trial
AimAdiponectin, a major adipokine secreted by adipose tissue, has been shown to improve insulin sensitivity. Myo-inositol hexaphosphate (phytate;...
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The relationship between sarcopenia and serum irisin and TNF-α levels in newly diagnosed cancer patients
ObjectiveSarcopenia in patients with cancer makes patients physically weak and adversely affects their compliance with treatment. In this study, we...
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Drug Survival of Tumor Necrosis Factor-Alpha Inhibitors and Switched Subsequent Biologic Agents in Patients with Psoriasis: A Retrospective Study
IntroductionThis study aimed to retrospectively examine the drug survival of tumor necrosis factor (TNF)-alpha inhibitors and switched subsequent...
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Etanercept-associated episcleritis: a pediatric case report of a paradoxical adverse reaction and review of the literature
Scleritis is an inflammation of the episcleral and scleral tissues, characterized by injection in both superficial and deep episcleral vessels. When...
