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Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders
The sirtuin family is a heterogeneous group of proteins that play a critical role in many cellular activities. Several degenerative diseases have...
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Assessment of bidirectional relationships between autoimmune diseases and primary ovarian insufficiency: insights from a bidirectional two-sample Mendelian randomization analysis
PurposeThe simultaneous occurrence of primary ovarian insufficiency (POI) and autoimmune diseases has been noted and debated in some epidemiological...
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The role of antibody glycosylation in autoimmune and alloimmune kidney diseases
Immunoglobulin glycosylation is a pivotal mechanism that drives the diversification of antibody functions. The composition of the IgG glycome is...
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Thoracic Involvement in Systemic Autoimmune Rheumatic Diseases: Pathogenesis and Management
Thoracic involvement is one of the main determinants of morbidity and mortality in patients with autoimmune rheumatic diseases (ARDs), with different...
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Myasthenia gravis and five autoimmune diseases: a bidirectional Mendelian randomization study
BackgroundThe association between myasthenia gravis (MG) and other autoimmune diseases is well established. In this study, we aimed to investigate...
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COVID-19 severity and vaccine breakthrough infections in idiopathic inflammatory myopathies, other systemic autoimmune and inflammatory diseases, and healthy controls: a multicenter cross-sectional study from the COVID-19 Vaccination in Autoimmune Diseases (COVAD) survey
ObjectivesWe aimed to compare the spectrum and severity of COVID-19 and vaccine breakthrough infections (BIs) among patients with IIMs, other...
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Anti-Ro52 Autoantibody Is Common in Systemic Autoimmune Rheumatic Diseases and Correlating with Worse Outcome when Associated with interstitial lung disease in Systemic Sclerosis and Autoimmune Myositis
This review highlights the 30 plus years research progress since the discovery of autoantibody to Ro52/TRIM21 in patients with systemic lupus...
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Fibroblast: A Novel Target for Autoimmune and Inflammatory Skin Diseases Therapeutics
Fibroblasts are crucial components of the skin structure. They were traditionally believed to maintain the skin’s structure by producing...
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The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases
Usual Interstitial Pneumonia (UIP) is characterized by progression of lung parenchyma that may be observed in various autoimmune rheumatic diseases...
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Ovarian dysfunction in adolescent girls with autoimmune rheumatic diseases
ObjectiveTo explore the different menstrual and pubertal abnormalities in adolescent females with systemic autoimmune rheumatic diseases (ARD).
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Active vaccination campaign to increase seasonal influenza vaccination coverage: a monocenter experience in a cohort of Italian patients with systemic autoimmune diseases
Seasonal influenza is a frequent cause of hospitalization and mortality among patients with systemic autoimmune diseases. Despite this evidence,...
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Epigenetic Dysregulation in Autoimmune and Inflammatory Skin Diseases
Epigenetics is the study of heritable, reversible gene expression patterns that do not originate from alterations in the DNA sequence. Epigenetic...
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Sleep Disturbances in Autoimmune Neurological Diseases
Purpose of ReviewTo summarize the current evidence on the associations between autoimmune neurological diseases (e.g., multiple sclerosis, myasthenia...
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Omicron variant dominance and anti-SARS-CoV-2 vaccination are key determinants for a milder course of COVID-19 in patients with systemic autoimmune rheumatic diseases
IntroductionThis study aimed to determine whether the introduction of anti-SARS-CoV-2 vaccines and the dominance of the omicron variant had a...
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Immunogenicity and safety of the mRNA-based BNT162b2 vaccine in systemic autoimmune rheumatic diseases patients
BackgroundThe COVID-19 outbreak has led to the rapid development and administration of the COVID-19 vaccines worldwide. Data about the immunogenicity...
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Investigation of the Causal Relationship Between Autoimmune Diseases and Premature Ovarian Insufficiency
BackgroundPOI is a multifactorial disease due to lack of estrogen resulting in symptoms such as insomnia, osteoporosis, and voiding disorders. For...
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Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19
Evidence supporting the extra-skeletal role of vitamin D in modulating immune responses is centred on the effects of its final metabolite,...
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Treatment-resistant depression and risk of autoimmune diseases: evidence from a population-based cohort and nested case-control study
Recent literature indicates that patients with depression had increased immune activation. We hypothesised that treatment-resistant depression (TRD),...
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Frequency, proportion of PF-ILD, and prognostic factors in patients with acute exacerbation of ILD related to systemic autoimmune diseases
BackgroundAcute exacerbation (AE) of systemic autoimmune disease-related interstitial lung diseases (SAID-ILD) is less common than AE of idiopathic...
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The role of lysosomes in metabolic and autoimmune diseases
Lysosomes are catabolic organelles that contribute to the degradation of intracellular constituents through autophagy and of extracellular components...
