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Hypertension in diabetes
Diabetes mellitus, a disease that affects hundreds of millions of people worldwide, is increasing in prevalence in all age groups, including children...
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Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results
The renin-angiotensin-aldosterone system (RAAS) is a regulatory mechanism of the endocrine system and is associated with various diseases, including...
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Effect of exercise training on the renin–angiotensin–aldosterone system: a meta–analysis
Blood pressure (BP) management reduces the risk of cardiovascular disease (CVD). The renin–angiotensin–aldosterone system (RAAS) plays an important...
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Diminazene aceturate or losartan ameliorates the functional, radiological and histopathological alterations in knee osteoarthritis rodent model: repurposing of the ACE2/Ang1-7/MasR cascade
PurposeCurrent therapies for osteoarthritis (OA) are limited to analgesics and anti-inflammatory drugs. Considering the importance of oxidative...
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Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies
BackgroundThe recent progress in molecular biology generates an increasing interest in investigating molecular biomarkers as markers of response to...
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Effects of very low-calorie ketogenic diet on hypothalamic–pituitary–adrenal axis and renin–angiotensin–aldosterone system
BackgroundThe hypothalamic–pituitary–adrenal (HPA) axis is a neuroendocrine system involved in controlling stress responses in humans under...
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Comparing Renin-Angiotensin-Aldosterone Blockade Regimens for Long-Term Chemotherapy-Related Cardiac Dysfunction: A Network Meta-Analysis
PurposeCancer therapies including trastuzumab and anthracyclines are cardiotoxic and cause cardiac dysfunction. To prevent cardiotoxicity,...
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Managing Heart Failure in Chronic Kidney Disease: A Review of Current Literature
Purpose of ReviewThe purpose of this review was to discuss recent literature pertaining to the management of heart failure (HF) in patients with...
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Management of Hypertension in the Asia-Pacific Region: A Structured Review
This article reviews available evidence regarding hypertension management in the Asia-Pacific region, focussing on five research questions that deal...
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Renin–Angiotensin–Aldosterone Inhibitors and COVID-19 Infection
Purpose of ReviewThis review summarises the literature data and provides an overview of the role and impact of the use of...
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Evaluating the effect of vitamin D supplementation on serum levels of 25-hydroxy vitamin D, 1,25-dihydroxy vitamin D, parathyroid hormone and renin–angiotensin–aldosterone system: a systematic review and meta-analysis of clinical trials
BackgroundVitamin D, one of the most essential micronutrients, is crucial in various health outcomes. However, previous studies showed conflicting...
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Progressionshemmung bei chronischen Nierenerkrankungen
Chronic kidney disease (CKD) affects about 10–15% of the German population with a steady increase. It is assumed that CKD will become the 5th most...
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Arterial stiffness and hypertension
Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by...
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Clinical course and management of children with IgA vasculitis with nephritis
BackgroundIgA vasculitis is the most common vasculitis in children and is often complicated by acute nephritis (IgAVN). Risk of chronic kidney...
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Nierenarterienstenose
Patients should only be screened for renal artery stenosis when they have an increased likelihood for develo** stenosis and relevant clinical...
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Effect of sodium–glucose transporter 2 inhibitor empagliflozin on proteinuria and kidney function progression in patients with non-diabetic glomerulonephritis: a pilot superiority randomized controlled trial
BackgroundAmelioration of proteinuria is one of main treatment targets in patients with glomerulonephritis, yet the remission rates are suboptimal.
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Differential expression of the angiotensin receptors (AT1, AT2, and AT4) in the placental bed of HIV-infected preeclamptic women of African ancestry
The Renin-Angiotensin-Aldosterone System (RAAS) is implicated in the pathophysiology of preeclampsia (PE). There is a paucity of data on...
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Increased cardiovascular risk in patients with chronic kidney disease
Cardiovascular disease (CVD) is highly prevalent in patients suffering from chronic kidney disease (CKD). The risk of patients with CKD develo**...
