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Sedation and cerebrovascular reactivity in traumatic brain injury: another potential avenue for personalized approaches in neurocritical care?
BackgroundImpaired cerebrovascular reactivity appears to be linked to worse global outcome in adult traumatic brain injury (TBI). Literature suggests...
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Universal Mindfulness Training in Schools for Adolescents: a Sco** Review and Conceptual Model of Moderators, Mediators, and Implementation Factors
There is evidence that universal school-based mindfulness training (SBMT) can have positive effects for young people. However, it is unknown who...
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Brimonidine eye drops reveal diminished sympathetic pupillary tone in comatose patients with brain injury
BackgroundThere is an urgent need for easy-to-perform bedside measures to detect residual consciousness in clinically unresponsive patients with...
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Prevalence and Risk Factors for Intensive Care Unit Delirium After Traumatic Brain Injury: A Retrospective Cohort Study
BackgroundDelirium remains understudied after traumatic brain injury (TBI). We sought to identify independent predictors of delirium among intensive...
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Resting-State EEG Signature of Early Consciousness Recovery in Comatose Patients with Traumatic Brain Injury
BackgroundResting-state electroencephalography (rsEEG) is usually obtained to assess seizures in comatose patients with traumatic brain injury (TBI)....
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Neurological Pupil Index as an Indicator of Neurological Worsening in Large Hemispheric Strokes
Background/ObjectiveCerebral herniation due to brain edema is the major cause of neurological worsening in patients suffering large hemispheric...
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Anisocoria without extraocular muscle impairment due to moderate traumatic brain injury with midbrain contusion: a case report
BackgroundNew-onset anisocoria is an important clinical clue to life-threatening intracranial injury. Anisocoria alone without impairment of...
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A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing
BackgroundPseudorabies virus (PRV) was thought to only infect animals. Recent studies have shown that it can also infect human.
Case presentation ...
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Prediction of neurocritical care intensity through automated infrared pupillometry and transcranial doppler in blunt traumatic brain injury: the NOPE study
PurposeThis pilot study aimed to determine the capacity of automated infrared pupillometry (AIP) alone and in combination with transcranial doppler...
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Clinical Outcome of Patients with Poor-Grade Aneurysmal Subarachnoid Hemorrhage with Bundled Treatments: A Propensity Score-Matched Analysis
BackgroundPoor-grade aneurysmal subarachnoid hemorrhage (aSAH), defined as Hunt and Hess (HH) grades IV and V, is a challenging disease because of...
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Central retina plays a decisive role in the suppression of pupillary escape
PurposeTo explore the pupil redilation during persistent light exposure (pupillary escape phenomenon) at the macula and periphery with monochromatic...
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Influence of ocular biometric factors on the defocus curve in an enlarged depth-of-focus intraocular lens
BackgroundTo assess the influence of biometric measurements on the defocus curve after the implantation of enlarged depth-of-focus (EDoF) intraocular...
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Effects of Osmotic Therapy on Pupil Reactivity: Quantification Using Pupillometry in Critically Ill Neurologic Patients
BackgroundOsmotic therapy is a critical component of medical management for cerebral edema. While up to 90% of neurointensivists report using these...
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Utility of Early Magnetic Resonance Imaging to Enhance Outcome Prediction in Critically Ill Children with Severe Traumatic Brain Injury
BackgroundMany children with severe traumatic brain injury (TBI) receive magnetic resonance imaging (MRI) during hospitalization. There are...
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Resting pupil size is a predictor of hypotension after induction of general anesthesia
PurposeArterial hypotension is a major adverse effect of general anesthesia. Patients with pre-existing autonomic dysfunction are at greater risk of...
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The combination of arterial lactate level with GCS-pupils score to evaluate short term prognosis in traumatic brain injury: a retrospective study
BackgroundThe aim of the study was to determine whether the combination of Glasgow Coma Scale (GCS) and Pupil responses score (GCSP) with arterial...
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A potential role for inflammatory cytokines in a rare late-onset capsular block syndrome: a case report
BackgroundLate-onset capsule block syndrome (CBS) is a rare complication of cataract phacoemulsification and the implantation of a posterior chamber...
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Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury
BackgroundOptimal cerebral perfusion pressure (CPPopt) has emerged as a promising personalized medicine approach to the management of...
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The use of quantitative pupillometry in patients with pituitary tumors: a technical note
BackgroundPituitary tumors may cause compression of the optic chiasm, resulting in decreased visual acuity. Therefore, decompression of the optic...
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Quantitative assessments of pupillary light reflexes in hospital-onset unresponsiveness
BackgroundPatients who develop hospital-onset unresponsiveness should be promptly managed in order to avoid clinical deterioration. Pupillary...
