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Correction to: Review of Transthyretin Silencers, Stabilizers, and Fibril Removal Agents in the Treatment of Transthyretin Cardiac Amyloid
On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every...
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Patisiran: First Global Approval
Patisiran (ONPATTRO™) is a double-stranded small interfering RNA encapsulated in a lipid nanoparticle for delivery to hepatocytes. By specifically...
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Correction to: Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis
The original version of this article unfortunately contained a mistake.
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Correction to: A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis
The middle initial of one of the authors, Alan Kaye, was missed in the original publication.
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Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis
Silencing the transthyretin ( TTR ) gene is an effective strategy in the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis. Vutrisiran...
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Treatment characteristics of patients with hereditary transthyretin amyloidosis: a cohort study
BackgroundThere are novel medications approved for the treatment of hereditary transthyretin amyloidosis (ATTRv), classified as transthyretin (TTR)...
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Update on Amyloid Polyneuropathy and Treatment
Purpose of ReviewThe purpose of this review is to summarize currently available and develo** diagnostic and treatment options for hereditary...
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Emerging Therapies for Transthyretin Amyloidosis
Purpose of ReviewThis review provides an overview of the available therapies for treating neuropathic and/or cardiac manifestations of transthyretin...
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Molecular mechanisms and emerging therapies in wild-type transthyretin amyloid cardiomyopathy
Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is an underrecognized cause of heart failure due to misfolded wild-type transthyretin...
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Advances in the Diagnosis and Management of Transthyretin Amyloid Cardiomyopathy
Purpose of reviewTransthyretin amyloid cardiomyopathy (ATTR-CM) is a disease with high morbidity and mortality. This disease is significantly...
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Kardiale ATTR-Amyloidose
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed cause of heart failure and arrhythmia. This differential diagnosis should...
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Disease-Modifying Pharmacological Therapies for Transthyretin Cardiac Amyloidosis
Transthyretin-related cardiac amyloidosis is a disease that is poorly understood and challenging to manage; however, pharmacotherapeutic developments...
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Peripheral neuropathy secondary to a ‘domino’ liver transplant: a case report
BackgroundPeripheral neuropathy caused by amyloidosis is one of the well-recognised sequelae of mutations in the transthyretin gene ( TTR ).
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Tafamidis therapy in transthyretin amyloid cardiomyopathy: a narrative review from clinical trials and real-world evidence
BackgroundAmyloidosis is a heterogeneous group of disorders caused by the extracellular deposition of insoluble misfolded proteins, leading to...