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Challenges of paediatric palliative care in Romania: a focus groups study
BackgroundThe availability of palliative care facilities for children vary considerably among the European member states. In Romania, a country where...
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Diversity in Oncology Clinical Trials: Current Landscape for Industry-Sponsored Clinical Trials in Asia
IntroductionThere has been a growing recognition on the importance of diversity in clinical trials. Existing research has highlighted a significant...
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Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0
Positron emission tomography (PET) has been widely used in paediatric oncology. 2-Deoxy-2-[ 18 F]fluoro-D-glucose ([ 18 F]FDG) is the most commonly used...
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A retrospective study of conjunctival lesions in the Paediatric Eye Clinic over 12 years
BackgroundPaediatric conjunctival lesions are rare and diverse. Though often indolent and asymptomatic, they can in some cases be sight or...
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Paediatric cancer patients with severe sepsis or septic shock at the PICU with positive microbiological results do worse than those with negative results: a retrospective cohort study
PurposeInfections are a leading cause of mortality and morbidity in paediatric cancer patients. The aim of this study was to determine whether...
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Determinants of bone parameters in young paediatric cancer survivors: the iBoneFIT project
BackgroundBone health is remarkably affected by endocrine side effects due to paediatric cancer treatments and the disease itself. We aimed to...
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Dialysis for paediatric acute kidney injury in Cape Town, South Africa
BackgroundDialysis is lifesaving for acute kidney injury (AKI), but access is poor in less resourced settings. A “peritoneal dialysis (PD) first”...
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Molecular tumour boards — current and future considerations for precision oncology
Over the past 15 years, rapid progress has been made in developmental therapeutics, especially regarding the use of matched targeted therapies...
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The role of artificial intelligence in paediatric neuroradiology
Imaging plays a fundamental role in the managing childhood neurologic, neurosurgical and neuro-oncological disease. Employing multi-parametric MRI...
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Goal-directed therapeutic exercise for paediatric posterior fossa brain tumour survivors: a qualitative analysis of experiences
PurposeTo explore child and parent experiences of a 12-week goal-directed therapeutic exercise intervention in paediatric posterior fossa brain...
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A successful centre for translational paediatric surgical research
The National Children’s Research Centre (NCRC), the single largest paediatric research centre in Ireland, has been in existence for over 50 years...
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The BOOST paediatric advance care planning intervention for adolescents with cancer and their parents: development, acceptability and feasibility
BackgroundAlthough advance care planning (ACP) has been widely recommended to support patient and family engagement in understanding the patient’s...
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Diffuse paediatric cerebellar glioma: two identical imaging phenotypes of an extremely rare entity with disparate pathology
Although the posterior fossa is a common location for paediatric brain tumours [
1 ], diffuse glioma isolated to the cerebellum is an extremely rare...
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Perspectives of healthcare professionals on the use of immersive virtual reality in teenage and young adult oncology: a qualitative interview study
BackgroundApplications of Virtual Reality (VR) in healthcare continue to grow at a rapid pace, yet the challenges and opportunities associated with...
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Fluid management and active fluid removal practices: a global survey of paediatric critical care physicians
AimsFluid accumulation (FA) in critically ill children is associated with poor clinical outcomes. While conservative fluid management has been...
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Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers
Rare but recurrent mutations in the fibroblast growth factor receptor (FGFR) pathways, most commonly in one of the four FGFR receptor tyrosine kinase...
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Evaluation of UK paediatric nephrology teams’ understanding, experience and perceptions of oral health outcomes and accessibility to dental care: a mixed-methods study
BackgroundOral health conditions are common in children and young people (CYP) with kidney disorders. There is currently limited literature on how...
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Should I call psycho-oncology? Training nurses on psycho-oncological screening reduces uncertainties
PurposePsycho-oncological screening is required to identify distressed patients and direct them to psycho-oncological care. In practice, screening...
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Risk Factors Associated with Medication Administration Errors in Children: A Prospective Direct Observational Study of Paediatric Inpatients
IntroductionLimited evidence exists regarding medication administration errors (MAEs) on general paediatric wards or associated risk factors exists.
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Functional outcomes at PICU discharge in hemato-oncology children at a tertiary oncology center in Hong Kong
BackgroundAdvancements in cancer treatment have resulted in longer survival but often at the expense of new therapy-associated morbidities. The aim...
