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Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma
BackgroundOptic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells...
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Early diffusion-weighted MRI at 3 Tesla detects ischemic changes of the optic nerve in anterior ischemic optic neuropathy
ObjectivesTo assess the impact of timing from visual symptoms’ onset to diffusion-weighted (DW) 3 T MRI completion to detect ischemic changes of the...
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Complications and visual outcomes following surgical resection of pediatric optic pathway/hypothalamic gliomas: a systematic review and meta-analysis
Pediatric optic pathway/hypothalamic gliomas (OPHG) pose challenges in treatment due to their location and proximity to vital structures. Surgical...
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Ventral subiculum promotes wakefulness through several pathways in male mice
The ventral subiculum (vSUB), the major output structure of the hippocampal formation, regulates motivation, stress integration, and anxiety-like...
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Is the OCT a predictive tool to assess visual impairment in optic chiasm compressing syndrome in pituitary macroadenoma? A prospective longitudinal study
Visual dysfunction is a prevalent symptom in patients with non-functioning pituitary macroadenoma (NFPM); the role of OCT in such patients has not...
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Unusual pattern of herpetic optic neuropathy: a case report and literature review of the pathophysiology of herpetic uveitis
Herpetic uveitis is a relatively common type of intraocular inflammation with a broad spectrum of manifestations ranging from mild anterior uveitis...
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Traumatic optic neuropathy: a review of current studies
Traumatic optic neuropathy (TON) is a serious complication of craniofacial trauma that directly or indirectly damages the optic nerve and can cause...
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Is the clinical course of non-arteritic ischemic optic neuropathy associated with oxidative damage and the dynamics of the antioxidant response?
PurposeOxidative stress is known to be a decisive factor in the wide etiopathogenesis of optic neuropathy. This study aimed to comprehensively...
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Vascular features around the optic disc in familial exudative vitreoretinopathy: findings and their relationship to disease severity
BackgroundFamilial exudative vitreoretinopathy (FEVR) is a rare congenital disorder of retinal vascular development. We aimed to study the vascular...
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Fractional anisotropy helps to differentiate the optic nerve impairment between neuromyelitis optica spectrum disorders and multiple sclerosis
ObjectivesTo assess the characteristics of optic nerve impairment between neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS)...
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Park7 protects retinal ganglion cells and promotes functional preservation after optic nerve crush via regulation of the Nrf2 signaling pathway
PurposeWe aim to investigate the effect of Park7 on mice RGC survival and function following optic nerve crush (ONC), and to explore its potential...
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Endoscopic ultrasonic aspiration as alternative to more invasive surgery in initial management of optic pathway gliomas in children
IntroductionOptic pathway gliomas (OPGs) presenting with acute hydrocephalus represent a true neurosurgical and neurooncological challenge. Two main...
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Scintillating scotoma following optic nerve compression caused by an unruptured anterior communicating artery aneurysm: a case report
BackgroundScintillating scotoma caused by optic nerve compression by aneurysm is rare. We report a case of scintillating scotoma following optic...
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Mesenchymal stem cells (MSCs) in Leber’s hereditary optic neuropathy (LHON): a potential therapeutic approach for future
BackgroundOptic neuropathy has become a new typical syndromic multi-system disease that leads to optic atrophy. This review discusses potential...
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Acute disseminated encephalomyelitis with bilateral optic neuritis following ChAdOx1 COVID-19 vaccination
BackgroundAcute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory demyelinating disease of the central nervous system. We...
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Tensor- and high-resolution fiber tractography for the delineation of the optic radiation and corticospinal tract in the proximity of intracerebral lesions: a reproducibility and repeatability study
PurposeFiber tracking (FT) is used in neurosurgical planning for the resection of lesions in proximity to fiber pathways, as it contributes to a...
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Aberrant spontaneous brain activity in patients with thyroid-associated ophthalmopathy with and without optic neuropathy: a resting-state functional MRI study
ObjectivesTo investigate the brain functional alterations in dysthyroid optic neuropathy (DON) by evaluating spontaneous neural activity, using...
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Multiple sclerosis optic neuritis and trans-synaptic pathology on cortical thinning in people with multiple sclerosis
BackgroundThe multi-order visual system represents an excellent testing site regarding the process of trans-synaptic degeneration. The presence and...
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Memantine administration in patients with optic neuritis: a double blind randomized clinical trial
IntroductionAs an inflammatory phenomenon, optic neuritis (ON) that causes demyelination in the optic nerve damages the retinal cells, and leads to...
