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Hsa_circ_0041150 serves as a novel biomarker for monitoring chemotherapy resistance in small cell lung cancer patients treated with a first-line chemotherapy regimen
PurposeTo explore the potential of circRNAs as biomarkers in non-invasive body fluids for monitoring chemotherapy resistance in SCLC patients.
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Neoadjuvant Chemotherapy Followed by Surgery in Figo Stage IB2, IIA2, and IIB Cervical Cancer—Survival Analysis
PurposeEarly-stage bulky cancers of the cervix and locally advanced cancer (defined as FIGO 2009 Stages IB2, IIA2 and IIB) form a distinctive subset...
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Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities
Cytotoxic chemotherapy remains a key modality in cancer treatment. These therapies, successfully used for decades, continue to transform the lives of...
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Tailoring Adjuvant Chemotherapy to Biologic Response Following Neoadjuvant Chemotherapy Impacts Overall Survival in Pancreatic Cancer
BackgroundThe role of postoperative chemotherapy in patients with resected pancreatic cancer who receive neoadjuvant treatment is unknown. Clinicians...
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Tislelizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy as First-Line Treatment for Chinese Patients with Advanced Esophageal Squamous Cell Carcinoma: A Cost-Effectiveness Analysis
Background and ObjectivesAdvanced esophageal squamous cell carcinoma (ESCC) is a prevalent and highly malignant tumor with a poor prognosis....
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Difficulty of adjuvant chemotherapy administration in patients with biliary tract cancer
PurposeThis study aimed to elucidate the difficulty of adjuvant chemotherapy administration in patients with biliary tract carcinoma (BTC).
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Total Neoadjuvant Therapy in Rectal Cancer: Multi-center Comparison of Induction Chemotherapy and Long-Course Chemoradiation Versus Short-Course Radiation and Consolidative Chemotherapy
BackgroundTotal neoadjuvant therapy for locally advanced rectal cancer may include induction chemotherapy and chemoradiation or short-course...
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Platinum-based chemotherapy in metastatic prostate cancer: what possibilities?
Metastatic prostate cancer is a major health burden worldwide, necessitating the continuous development of effective treatment strategies. Androgen...
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Trimethoprim-sulfamethoxazole prevents interstitial pneumonitis in B-cell lymphoma patients receiving chemotherapy: a propensity score matching analysis
B-cell lymphoma is the most prevalent type of non-Hodgkin lymphoma, for which the standard treatment regimen includes rituximab combined with CHOP....
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Chemotherapy periodization to maximize resistance training adaptations in oncology
IntroductionEngaging in exercise programs during cancer treatment is challenging due to the several chemotherapy-induced side effects. Using a...
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AKR1C4 regulates the sensitivity of colorectal cancer cells to chemotherapy through ferroptosis modulation
PurposeColorectal cancer (CRC) remains a major global health concern, necessitating innovative therapeutic strategies to enhance treatment efficacy....
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Spectral CT vs. diffusion-weighted imaging for the quantitative prediction of pathologic response to neoadjuvant chemotherapy in locally advanced gastric cancer
ObjectivesTo compare the performance of spectral CT and diffusion-weighted imaging (DWI) for predicting pathologic response after neoadjuvant...
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Chemotherapy-induced thrombocytopenia: literature review
Chemotherapy-induced thrombocytopenia (CIT) is a common condition that frequently results in reduced chemotherapy dosages, postponed treatment,...
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Survival Benefit of Induction Chemotherapy with Paclitaxel and Carboplatin Followed by Chemoradiation Versus Postoperative Treatment in Locally Advanced Gastric Cancer: A Retrospective Cohort Study
BackgroundGastric cancer remains a prevalent worldwide illness that lacks a definitive cure. Recently, induction chemotherapy followed by concurrent...
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The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma—a pooled trials analysis
Mantle cell lymphoma (MCL) is a distinct subtype of B-cell lymphoma and commonly used induction immunochemotherapies include the anti-CD20 antibody...
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Predictive analysis of breast cancer response to neoadjuvant chemotherapy through plasma metabolomics
PurposePreoperative chemotherapy is a critical component of breast cancer management, yet its effectiveness is not uniform. Moreover, the adverse...
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Effect of duration of adjuvant chemotherapy with S-1 (6 versus 12 months) for resected pancreatic cancer: the multicenter clinical randomized phase II postoperative adjuvant chemotherapy S-1 (PACS-1) trial
BackgroundSix-month adjuvant chemotherapy with S-1 is standard care for resected pancreatic cancer in Japan; however, the optimal duration has not...
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The Role of Neoadjuvant and Adjuvant Chemotherapy in Pancreatic Cancer
Pancreatic cancer is an aggressive malignancy. Recurrences are very high despite high-quality surgery necessitating adjuvant therapy. The evolution...
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Exposure to Neoadjuvant Oxaliplatin-Containing Chemotherapy, Does it Effect Intraperitoneal Hyperthermic Chemotherapy Perfusion?
IntroductionPatients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) are commonly exposed to oxaliplatin...
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Management of hematological patients requiring emergency chemotherapy in the intensive care unit
Hematological malignancies may require rapid-onset treatment because of their short doubling time, notably observed in acute leukemias and specific...
