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A Microsimulation Model to Project the 5-Year Impact of Using Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Acute Flares
BackgroundHyperbaric oxygen therapy (HBOT) improves short-term outcomes for ulcerative colitis (UC) patients hospitalized for acute flares....
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A multimorbidity model for estimating health outcomes from the syndemic of injection drug use and associated infections in the United States
BackgroundFatal drug overdoses and serious injection-related infections are rising in the US. Multiple concurrent infections in people who inject...
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Lifetime Burden of Adult Congenital Heart Disease in the USA Using a Microsimulation Model
Congenital heart defects (CHD) represent a growing burden of illness among adults. We estimated the lifetime health, education, labor, and social...
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Effect and cost-effectiveness of national gastric cancer screening in Japan: a microsimulation modeling study
BackgroundA national endoscopic screening program for gastric cancer was rolled out in Japan in 2015. We used a microsimulation model to estimate the...
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External Validation of the BRAVO Diabetes Model Using the EXSCEL Clinical Trial Data
IntroductionWe have developed the Building, Relating, Assessing, and Validating Outcomes (BRAVO) diabetes model, an individual-level, discrete-time...
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Methods for health workforce projection model: systematic review and recommended good practice reporting guideline
BackgroundHealth workforce projection models are integral components of a robust healthcare system. This research aims to review recent advancements...
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Collaborating with Patient Partners to Model Clinical Care Pathways in Major Depressive Disorder: The Benefits of Mixing Evidence and Lived Experience
BackgroundPartnering with patients can enrich the design and development of models of clinical care pathways, yet the practice is not commonplace....
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Cost-Effectiveness of Routine Monitoring of Long-Term Conditions in Primary Care: Informing Decision Modelling with a Systematic Review in Hypertension, Type 2 Diabetes and Chronic Kidney Disease
BackgroundLong-term conditions (LTCs) are major public health problems with a considerable health-related and economic burden. Modelling is key in...
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A model-based cost-effectiveness analysis of fracture liaison services in China
SummaryThis study is a model-based cost-effectiveness analysis of fracture liaison services (FLS) in China, suggesting that FLS could potentially...
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Financing Thresholds for Sustainability of Community Health Worker Programs for Patients Receiving Medicaid Across the United States
States have turned to novel Medicaid financing to pay for community health worker (CHW) programs, often through fee-for-service or capitated...
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Estimating the future clinical and economic benefits of improving osteoporosis diagnosis and treatment among women in China: a simulation projection model from 2020 to 2040
SummaryAnnual osteoporotic fractures is projected to increase by 135% from 6.9 M (2020) to 16.2 M (2040), increasing the economic burden by 121% from...
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The health and economic impact of implementation strategies for improving detection of hereditary cancer patients—protocol for an in-depth cost-effectiveness evaluation with microsimulation modelling
BackgroundPatients with Lynch syndrome (an inherited cancer predisposition syndrome) remain largely underdiagnosed despite clinically and...
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Estimating the future clinical and economic benefits of improving osteoporosis diagnosis and treatment among women in South Korea: a simulation projection model from 2020 to 2040
SummaryUsing a microsimulation model, the impact of increased diagnosis and treatment of postmenopausal women with osteoporosis on anticipated...
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A progressive three-state model to estimate time to cancer: a likelihood-based approach
BackgroundTo optimize colorectal cancer (CRC) screening and surveillance, information regarding the time-dependent risk of advanced adenomas (AA) to...
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Estimating the future clinical and economic benefits of improving osteoporosis diagnosis and treatment among women in Japan: a simulation projection model from 2020 to 2040
SummaryImpact of increased osteoporosis diagnosis and treatment among postmenopausal women (PMW) on reduction in fractures and associated costs in...
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A Simple Cost-Effectiveness Model of Screening: An Open-Source Teaching and Research Tool Coded in R
Applied cost-effectiveness analysis models are an important tool for assessing health and economic effects of healthcare interventions but are not...
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Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis
SummaryThe Australian Health Economics Model of Osteoporosis (AusHEMO) has shown good face, internal and cross validities, and can be used to assist...
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Lifetime patient outcomes and healthcare utilization for Bronchopulmonary dysplasia (BPD) and extreme preterm infants: a microsimulation study
BackgroundBronchopulmonary dysplasia (BPD) is among the most severe chronic lung diseases and predominantly affects premature infants. There is a...
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Cost-effectiveness microsimulation of catheter-directed thrombolysis in submassive pulmonary embolism using a right ventricular function model
Approximately 30–50% of hemodynamically stable patients presenting with acute pulmonary embolism (PE) have evidence of right ventricular (RV)...
