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The role of fibroblast growth factor 23 in regulation of phosphate balance
Phosphate is essential for numerous biological processes, and serum levels are tightly regulated to accomplish these functions. The regulation of...
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Growth Factor Immobilization Strategies for Musculoskeletal Disorders
Purpose of ReviewTissue regenerative solutions for musculoskeletal disorders have become increasingly important with a growing aged population....
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An epidermal growth factor receptor compound mutation of L858R with S768I in advanced non-small-cell lung cancer: a case report
BackgroundIn the current treatment landscape for non-small cell lung cancers, epidermal growth factor receptor-tyrosine kinase inhibitors have...
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Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs
BackgroundPreterm infants show low blood levels of insulin-like growth factor 1 (IGF-1), known to be negatively correlated with Interleukin-6 (IL-6)....
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The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states
After decades of research in the neurobiology of IGF-I, its role as a prototypical neurotrophic factor is undisputed. However, many of its actions in...
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Efficacy of growth factor gene–modified stem cells for motor function after spinal cord injury in rodents: a systematic review and meta‑analysis
The efficacy of growth factor gene–modified stem cells in treating spinal cord injury (SCI) remains unclear. This study aims to evaluate the...
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Surgical resection of a retroperitoneal liposarcoma producing insulin-like growth factor II: a case report
BackgroundTumor-produced high molecular weight insulin-like growth factor-II (big insulin-like growth factor-II) is considered to cause non-islet...
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Serum vascular endothelial growth factor, insulin-like growth factor-1 and aflibercept levels in retinopathy of prematurity
PurposeTo evaluate the serum levels of vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) after intravitreal...
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Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system
The growth hormone/insulin growth factor-1 axis is a key endocrine system that exerts profound effects on metabolism by its actions on different...
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The role of transforming growth factor beta in bicuspid aortic valve aortopathy
A bicuspid aortic valve (BAV) is the most prevalent congenital cardiac deformity, which is associated with an increased risk to develop a thoracic...
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Successful intrahepatic cholangiocarcinoma conversion surgery after administration of fibroblast growth factor receptor inhibitor
We describe a case of a 47-year-old male patient with initially unresectable intrahepatic cholangiocarcinoma of the right liver lobe with tumor...
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Fibroblast growth factor 8 (FGF8) up-regulates gelatinase expression in chondrocytes through nuclear factor-κB p65
IntroductionGelatinases, namely MMP2 and MMP9, are involved in the natural turnover of articular cartilage, as well as the loss of the cartilage...
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The association between growth differentiation factor-15, erythroferrone, and iron status in thalassemic patients
BackgroundIron overload can result in grave consequences in thalassemic patients, despite the availability of iron chelators. Therefore, alternative...
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Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma
Background & aimsCombination immunotherapy refers to the use of immune checkpoint inhibitors (ICI) and molecular-targeted agents (MTA), which have...
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Maternal Uterine Artery Adenoviral Vascular Endothelial Growth Factor (Ad.VEGF-A165) Gene Therapy Normalises Fetal Brain Growth and Microglial Activation in Nutrient Restricted Pregnant Guinea Pigs
Fetal growth restriction (FGR) is associated with uteroplacental insufficiency, and neurodevelopmental and structural brain deficits in the infant....
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Role of transforming growth factor beta in assessment of severity of hypersensitivity pneumonitis: a single center study
BackgroundHypersensitivity pneumonitis (HP) is a more frequently diagnosed picture of diffuse parenchymal lung disease. It is an inflammation of the...
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TARDBP promotes ovarian cancer progression by altering vascular endothelial growth factor splicing
Disruptions in alternative splicing regulation play an essential role in ovarian cancer progression. However, the underlying mechanism remains...
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Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer
BackgroundThe level of tumor abnormal protein (TAP) level has a significant impact on tumor growth, recurrence, and metastasis. Previous studies have...
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Immunohistochemical expression of the hepatocyte growth factor in chromophobe renal cell carcinoma
BackgroundThe prognostic value of Hepatocyte growth factor (HGF) in non-clear cell renal cell carcinoma (RCC) is still unclear. The aim of this study...
