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Immunomodulatory and antiparasitic effects of garlic–arteether combination via nitric oxide pathway in Plasmodium berghei-infected mice
Many reports indicate medicinal value of garlic ( Allium sativum ), a popular herbal medicine used worldwide, and its therapeutic effect against...
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Diallyl trisulfide improves spinal cord ischemia–reperfusion injury damage by activating AMPK to stabilize mitochondrial function
BackgroundSpinal cord ischemia–reperfusion injury (SCII) is a catastrophic event, which can cause paraplegia in severe cases. In the reperfusion...
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Diallyl disulfide alleviates hypercholesterolemia induced by a western diet by suppressing endoplasmic reticulum stress in apolipoprotein E-deficient mice
BackgroundThe endoplasmic reticulum (ER) plays a pivotal role in maintaining cellular metabolic homeostasis. ER stress refers to the accumulation of...
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Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells
Diallyl disulfide (DADS), one of the main components of garlic, is well known to have anticancer effects on multiple cancers. However, its efficacy...
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Rumen fermentation and microbiota in Shami goats fed on condensed tannins or herbal mixture
BackgroundPhytochemical compounds can modify the rumen microbiome and improve rumen fermentation. This study evaluated the impact of supplementation...
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Evidence-based capacity of natural cytochrome enzyme inhibitors to increase the effectivity of antineoplastic drugs
AbstractCytochrome (CYP) enzymes catalyze the metabolism of numerous exogenous and endogenous substrates in cancer therapy leading to significant...
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Contact pemphigus: does it exist?
The entity “contact pemphigus” has been recognized for more than 50 years, however existence of the disease, which is opposed and supported by many,...
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Joint Effects Between CDKN2B/P15 Methylation and Environmental Factors on the Susceptibility to Gastric Cancer
BackgroundThe incidence of gastric cancer has long been at a high level in China, seriously affecting the health of Chinese people.
Aims ...
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Comparative study between chemical anticoccidial medication and natural prepared products on experimentally infected broiler chickens
This study was conducted in order to compare well established used chemical anticoccidial medication (diclazuril) against natural prepared safe...
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Carbon dots as fluorescent nanoprobes for assay of some non-fluorophoric nitrogenous compounds of high pharmaceutical interest
BackgroundCarbon dots, CDs, have excellent photoluminescence properties, good biocompatibility, low toxicity and good light stability. The optical,...
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Associations between empirically derived dietary patterns and oxidative stress and inflammation in adults with primary hypothyroidism: a case-control study
BackgroundPrimary hypothyroidism is a common endocrine disorder caused by impaired production of thyroid hormones. Recent studies have shown that...
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Dietary supplements, cytochrome metabolism, and pharmacogenetic considerations
BackgroundDietary supplement use has continued to rise. In addition to supplement-drug interactions, it is prudent to consider how dietary...
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Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier
BackgroundLead (Pb) remains an apparently indispensable material in several industrial processes. It is a potent environmental toxin with associated...
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Dietary inflammatory index and risk of gallstone disease in Iranian women: a case-control study
BackgroundConsidering inflammation as a primary occurrence in gallstone formation, this study aimed to determine the relation between serum...
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The first reported mortality from aluminum phosphide poisoning in Lebanon: a case report
BackgroundAluminum phosphide is a commonly used pesticide, particularly in develo** countries where uncontrolled insecticides and pesticides are...
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Traditional uses and practices of edible cultivated Allium species (fam. Amaryllidaceae) in Sweden
BackgroundWhile the utilitarian crops grown in vicarage gardens in pre-industrial Sweden have been fairly well documented, our knowledge of plants...
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Pharmacological agents for the prevention of colistin-induced nephrotoxicity
BackgroundColistin is a polymyxin antibiotic which has been used for treatment of Gram-negative infections, but it was withdrawn due to its...
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Evaluating the effect of garlic extract on serum inflammatory markers of peritoneal dialysis patients: a randomized double-blind clinical trial study
BackgroundGarlic can be considered as a useful natural herb in inhibition of inflammation. The aim of this study was to assess the effectiveness of...
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Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?
Purpose of ReviewThe aim of this review is to summarize the available clinical efficacy and safety data related to the most studied and used...
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A review on corona virus and treatment approaches with Allium sativam
BackgroundRecently reported cases of Covid-19 globally remind us that new diseases are coming while we are unable to provide the treatment for the...
