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TOB is an effector of the hippocampus-mediated acute stress response
Stress affects behavior and involves critical dynamic changes at multiple levels ranging from molecular pathways to neural circuits and behavior....
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Ketamine and its enantiomers for depression: a bibliometric analysis from 2000 to 2023
Ketamine has demonstrated rapid and sustained antidepressant effects, marking its emergence as an innovative treatment of depression. Despite the...
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Olfactory impairment in autoimmune encephalitis: another piece of the puzzle
BackgroundDespite being long neglected, olfaction has recently become a focus of intense research in neuroscience, as smell impairment has been...
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Environmental enrichment alleviates hyperalgesia by modulating central sensitization in a nitroglycerin-induced chronic migraine model of mice
BackgroundChronic migraine (CM) is a debilitating neurofunctional disorder primarily affecting females, characterized by central sensitization....
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Characterizing the features and course of psychiatric symptoms in children and adolescents with autoimmune encephalitis
Autoimmune encephalitis (AE) can present like a psychiatric disorder. We aimed to illustrate the psychiatric manifestations, course and management of...
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Schnell wirksame Antidepressiva – neurobiologische Wirkprinzipien
Rapid-acting antidepressants disprove the dogma that antidepressants need several weeks to become clinically effective. Ketamine, the prototype of...
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Neurophysiological assessment of cortical activity in DEPDC5- and NPRL3-related epileptic mTORopathies
BackgroundMutations in the GATOR1 complex genes, DEPDC5 and NPRL3, play a major role in the development of lesional and non-lesional focal epilepsy...
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Movement disorders in autoimmune encephalitis: an update
Autoimmune encephalitis (AE) is a form of encephalitis resulting from an immune response targeting central nervous system antigens, which is...
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Glutamatergic and GABAergic anteroventral BNST projections to PVN CRH neurons regulate maternal separation-induced visceral pain
Early-life stress (ELS) is thought to cause the development of visceral pain disorders. While some individuals are vulnerable to visceral pain,...
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Recurrent/Metastatic Nasopharyngeal Carcinoma Treatment from Present to Future: Where Are We and Where Are We Heading?
Nasopharyngeal carcinoma (NPC) is distinct in its anatomic location and biology from other epithelial head and neck cancer (HNC). There are 3 WHO...
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Autoimmune encephalitis: what the radiologist needs to know
Autoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central nervous system. While...
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Differences and diversity of autoimmune encephalitis in 77 cases from a single tertiary care center
BackgroundThe incidence of autoimmune encephalitis has risen globally. There are two general categories of disease-associated antibodies that can be...
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Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder which has strong genetic basis. Despite the rapidly rising...
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Electroacupuncture at PC6 (Neiguan) Attenuates Angina Pectoris in Rats with Myocardial Ischemia–Reperfusion Injury Through Regulating the Alternative Splicing of the Major Inhibitory Neurotransmitter Receptor GABRG2
Angina pectoris is the most common manifestation of coronary heart disease, causing suffering in patients. Electroacupuncture at PC6 can effectively...
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DNA hydrolysing IgG catalytic antibodies: an emerging link between psychoses and autoimmunity
It is not uncommon to observe autoimmune comorbidities in a significant subset of patients with psychotic disorders, namely schizophrenia (SCZ) and...
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A case of GABAR antibodies in schizophrenia
BackgroundIn the last couple of years, schizophrenia was often discussed as autoimmune disease. Several antibodies were suspected, but so far there...
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Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis
BackgroundBrain impairment is one of a major complication of diabetes. Dietary flavonoids have been recommended to prevent brain damage. Astragalus...
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Anti-GAD epileptic encephalopathy in a toddler with Parry-Romberg syndrome
Parry-Romberg syndrome (PRS) is a progressive facial hemiatrophy often associated with severe epilepsy. Although an immune-mediated vasculitic...
