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Utility of Initial Tumor Reduction as a Prognostic Factor in Esophageal Squamous Cell Cancer Patients Undergoing Neoadjuvant Chemotherapy Followed by Surgery
BackgroundWhile a neoadjuvant chemotherapy regimen using docetaxel, cisplatin, and 5-fluorouracil (NAC-DCF) is considered the standard treatment for...
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Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma
Targeted therapy attempts are needed to enhance esophageal squamous cell carcinoma (ESCC) patients’ overall survival and satisfaction of life....
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LINC01004-SPI1 axis-activated SIGLEC9 in tumor-associated macrophages induces radioresistance and the formation of immunosuppressive tumor microenvironment in esophageal squamous cell carcinoma
Radioresistance and immunosuppression remain the major obstacles in the anti-cancer treatments. This work studies the functions of sialic acid...
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Prediction of malignant esophageal fistula in esophageal cancer using a radiomics-clinical nomogram
BackgroundMalignant esophageal fistula (MEF), which occurs in 5% to 15% of esophageal cancer (EC) patients, has a poor prognosis. Accurate...
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YAP inhibitor verteporfin suppresses tumor angiogenesis and overcomes chemoresistance in esophageal squamous cell carcinoma
PurposeTargeting angiogenesis is an attractive strategy for the effective treatment of cancer. This study aimed to investigate the anti-cancer...
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Optimal Time-to-Surgery Recommendations Based on Primary Tumor Volume Regression for Patients with Resectable Esophageal Cancer after Neoadjuvant Chemoradiotherapy: A Retrospective Study
BackgroundNeoadjuvant chemoradiotherapy (NCRT) has shown promise in improving the prognosis of individuals with locally advanced esophageal squamous...
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Huge esophageal gastrointestinal stromal tumor successfully resected under mediastino-laparoscopic transhiatal esophagectomy: a case report
BackgroundEsophageal gastrointestinal stromal tumors (E-GISTs) are often diagnosed early due to complaints such as dysphagia and are rarely found to...
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Potential Predictive Immune and Metabolic Biomarkers of Tumor Microenvironment Regarding Pathological and Clinical Response in Esophageal Cancer After Neoadjuvant Chemoradiotherapy: A Systematic Review
IntroductionThe tumor microenvironment (TME) plays a crucial role in therapy response and modulation of immunologic surveillance. Adjuvant...
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Prediction of Esophageal Stricture after Endoscopic Submucosal Dissection in Patients with Early Esophageal Cancer
BackgroundEndoscopic submucosal dissection (ESD) treatment of early esophageal cancer is effective and safe. It is currently the first-line treatment...
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Targeting EFNA1 suppresses tumor progression via the cMYC-modulated cell cycle and autophagy in esophageal squamous cell carcinoma
PurposeEsophageal squamous cell carcinoma (ESCC) remains one of the most common causes of cancer death due to the lack of effective therapeutic...
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Esophageal cancer in an adult with congenital esophageal stenosis: a case report
BackgroundCongenital esophageal stenosis (CES) is a rare condition. We encountered a case of esophageal cancer that developed in an adult with...
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Dissecting the inflammatory tumor microenvironment of esophageal adenocarcinoma: mast cells and natural killer cells are favorable prognostic factors and associated with less extensive disease
PurposeEsophageal adenocarcinoma (EAC) remains a challenging and lethal cancer entity. A promising target for new therapeutic approaches, as...
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How to update esophageal masses imaging using literature review (MRI and CT features)
AbstractMRI offers new opportunities for detailed visualization of the different layers of the esophageal wall, as well as early detection and...
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Non-endoscopic Screening for Esophageal Squamous Cell Carcinoma: Recent Advances
BackgroundEsophageal squamous cell carcinoma (ESCC) is one of the most common tumors in the gastrointestinal tract, and China has a high incidence...
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Predictive factors for esophageal stenosis in patients receiving prophylactic steroid therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma
BackgroundMethods to prevent esophageal stenosis (ES) after endoscopic submucosal dissection (ESD) for superficial esophageal squamous cell carcinoma...
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Safety and efficacy of endoscopic submucosal dissection for superficial esophageal cancer with esophageal varices
BackgroundHeavy drinking is associated with esophageal cancer and esophageal varices. However, there are limited reports of endoscopic resection for...
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The Impact of Pretreatment Esophageal Stenosis on Survival of Esophageal Cancer Patients
BackgroundLittle is known about the survival impacts of pretreatment cancerous stenosis on patients with esophageal carcinoma (EC).
Methods ...
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Quantitative CT analysis to predict esophageal fistula in patients with advanced esophageal cancer treated by chemotherapy or chemoradiotherapy
BackgroundEsophageal fistula is one of the most serious complications of chemotherapy or chemoradiotherapy (CRT) for advanced esophageal cancer. This...
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Thoracoscopy-Assisted Esophagectomy for Esophageal Leiomyomatosis
IntroductionDiffuse esophageal leiomyomatosis is a rare esophageal tumor characterized by circumferential thickening of smooth muscle layers of the...
