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Oncological and functional outcomes following treatment of T1a glottic squamous cell carcinoma with transoral laser microsurgery
BackgroundLaryngeal cancers of glottic origin comprise a large proportion of head and neck malignancies. Transoral laser microsurgery (TLM) and...
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A comparison of the survival between laser surgery and radiation in T1aN0M0 glottic cancer: a population-based analysis and meta-analysis
ObjectiveThe objective of this study is to compare the overall survival (OS) and the cancer-specific survival (CSS) for patients of T 1a N 0 M 0 glottic...
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A 6-Year Retrospective Study of the Demographics of Glottic Keratosis in a Tertiary Care Voice Centre
Since Keratosis may be accompanied with severe dysplasia or malignancy; early management of this condition is of essence. However, since this...
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T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence
PurposeWe assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC).
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VoiceS: voice quality after transoral CO2 laser surgery versus single vocal cord irradiation for unilateral stage 0 and I glottic larynx cancer—a randomized phase III trial
BackgroundSurgery and radiotherapy are well-established standards of care for unilateral stage 0 and I early-stage glottic cancer (ESGC). Based on...
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Multidimensional Voice Assessment After Management of Early Laryngeal Cancer: A Comparative Study
Laryngeal Squamous Cell Carcinoma is one of the most common head and neck cancers, and patients experience dysphonia after treatment with transoral...
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Transoral robotic cordectomy for glottic carcinoma: a rapid review
ObjectiveThe objective of this study was to investigate feasibility, surgical, oncological, and functional outcomes of transoral robotic cordectomy...
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Novel predictive tools and therapeutic strategies for patients with initially diagnosed glottic cancer in the United States
ObjectiveThe objective of this study is to identify valuable prognostic factors, build clinical prediction nomograms, and recommend the optimal...
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Prognosis and Outcomes in Early Stage Glottic Carcinoma Involving the Anterior Commissure Treated with Laser CO2 Surgery: A Retrospective Observational Analysis
The anterior commissure (AC) is the area where the vocal cords attach to the thyroid cartilage through Broyles’ ligament. Many authors argue that...
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Primary injection laryngoplasty after chordectomy for small glottic carcinomas
ObjectivesThe purpose of this study was to analyze the short- and middle-term effects of primary injection laryngoplasty in patients having tumor...
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Dosimetric comparison of three-dimensional conformal radiotherapy and static and dynamic intensity-modulated radiotherapy for the treatment of early-stage glottic cancer
BackgroundThe aim of this study was to compare dosimetric variations using the three-dimensional conformal radiotherapy (3DCRT), dynamic...
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Prognostic risk factors for initially diagnosed T2N0M0 glottic cancer: competing risk analysis and propensity-score matched cohort analysis
BackgroundPrognostic risk factors of patients with initially diagnosed T2N0M0 glottic cancer remain unclear. This study was aimed to conduct a...
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Impact of Transoral Radiofrequency Microsurgery and Radiotherapy on Long-term Swallowing Function in Patients with T1 Glottic Carcinoma
To compare the impact of transoral radiofrequency microsurgery (TRM) and radiotherapy (RT) on long-term swallowing function in patients with T1...
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The role of CD133 expression of cancer stem cells on radiotherapy response in early stage glottic cancers
PurposeTo investigate the relationship between CD133 positivity and radiotherapy (RT) response in early stage glottic laryngeal cancers.
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Oncologic results and quality of life in patients with T3 glottic cancer after transoral laser microsurgery
PurposeCO 2 transoral laser microsurgery (CO2 TOLMS) is an alternative approach to non-surgical organ preservation in selected T3 glottic squamous...
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Programmed death-ligand 1 and tumor-infiltrating lymphocytes (TILs) – low TIL density may predict poorer long-term prognosis in T1 laryngeal cancer
We evaluated the prognostic role of programmed death-ligand 1 (PD-L1) and tumor-infiltrating lymphocytes (TILs) in T1 glottic laryngeal squamous cell...
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Management of Laryngeal Dysplasia and Early Invasive Cancer
Dysplasia and early laryngeal cancer lie on a spectrum of cellular changes. These start with early changes to the cells including epithelial...
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Survival in an era of organ preservation: an update on laryngeal cancer in Ireland
BackgroundLaryngeal cancer epidemiology has changed in recent years, with falling incidence observed internationally. Organ preservation therapies...
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Role of Neck Dissection in Organ-Preservation for Glottic Squamous Cell Carcinoma
The surgical approach to the neck in laryngeal cancer depends on the tumor site and stage. Clinical practice guidelines recommend elective neck...
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Preoperative tracheotomy as reflection of tumor size impacting oncologic outcomes of patients with advanced stage glottic carcinoma
PurposeThe aim of this study was to evaluate the influence of preoperative tracheotomy on oncologic outcomes of advanced stage glottic carcinoma...
