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Sphenopalatine ganglion block with or without greater occipital nerve block for treatment of obstetric post-dural puncture headache after spinal anesthesia: randomized controlled trial
BackgroundConservative treatments of post-dural puncture headache (PDPH) may be unsuccessful, and the relief that is provided is frequently...
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Safety of local anesthetics in cervical nerve root injections: a narrative review
Severe neurological adverse events have been reported after fluoroscopically guided cervical nerve root injections. Particulate corticosteroids...
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Effects of preventative moxibustion at Shenque (CV8) and Guanyuan (CV4) on BDNF-TrkB pathway in the spinal dorsal horn and hypothalamus in rats with dysmenorrhea
ObjectiveTo observe the effects of preventative moxibustion on analgesia, substance P (SP), prostaglandin (PG) F 2α and PGE 2 in rats with...
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Intrathecal gastrodin alleviates allodynia in a rat spinal nerve ligation model through NLRP3 inflammasome inhibition
BackgroundGastrodin (GAS), a main bioactive component of the herbal plant, Gastrodia elata Blume, has shown to have beneficial effects on...
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Exploring the effect of Tuina on the dendritic structure of spinal cord dorsal horn in rats with lumbar disc herniation based on NR2B/PSD-95 pathway
ObjectiveTo investigate the analgesic mechanism of Tuina (Chinese therapeutic massage) by observing the effect of the N-methyl-D-aspartate receptor...
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LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion
BackgroundTrigeminal nerve injury is one of the most serious complications in oral clinics, and the subsequent chronic orofacial pain is a...
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Complex Regional Pain Syndrome: Updates and Current Evidence
Purpose of ReviewComplex regional pain syndrome (CRPS) is a debilitating condition that manifests with sensory, neurologic, autonomic, and/or trophic...
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Trace amine-associated receptor 1 regulation of Kv1.4 channels in trigeminal ganglion neurons contributes to nociceptive behaviors
BackgroundTrace amines, such as tyramine, are endogenous amino acid metabolites that have been hypothesized to promote headache. However, the...
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Dorsal root ganglion pulsed radiofrequency treatment for chronic cervical radicular pain: a retrospective review of outcomes in fifty-nine cases
AbstractPulsed radiofrequency treatment adjacent to the cervical dorsal root ganglion is used to treat persistent cervical radicular pain that has...
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Real-time ultrasound-guided stellate ganglion block for migraine: an observational study
ObjectiveTo observe whether ultrasound-guided stellate ganglion block (SGB) can effectively relieve migraine pain and improve the quality of migraine...
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Analysis of Efficacy and Factors Associated with Reccurence After Radiofrequency Thermocoagulation in Patients with Postherpetic Neuralgia: a Long-Term Retrospective and Clinical Follow-Up Study
IntroductionPostherpetic neuralgia (PHN) is a painful condition that persists for 1 month or more after herpes zoster rash has healed. Radiofrequency...
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Adiponectin receptor 1-mediated stimulation of Cav3.2 channels in trigeminal ganglion neurons induces nociceptive behaviors in mice
BackgroundAdipokines, including adiponectin, are implicated in nociceptive pain; however, the underlying cellular and molecular mechanisms remain...
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Interventional Pain Management in the Treatment of Chronic Pelvic Pain
Purpose of ReviewChronic pelvic pain syndrome (CPPS) is a common yet complex disease in the field of urology, gynecology, and pain management. This...
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Current Neurostimulation Therapies for Chronic Pain Conditions
Purpose of ReviewNeurostimulation treatment options have become more commonly used for chronic pain conditions refractory to these options. In this...
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Eight-year chronic wound caused by Tarlov’s cyst: a case report
BackgroundTarlov’s cyst is often underdiagnosed since it is difficult to identify without imaging assistance. Herein, we report the case of a young...
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Interventional Treatment Modalities for Chronic Abdominal and Pelvic Visceral Pain
Purpose of ReviewChronic abdominal and pelvic visceral pain is an oftentimes difficult to treat pain condition that requires a multidisciplinary...
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Pulsed radiofrequency of the C2 dorsal root ganglion and epidural steroid injections for cervicogenic headache
BackgroundCervicogenic headache (CEH) is characterized by unilateral headache symptoms referred to the head from the cervical spine. Few methods have...
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Celecoxib alleviates nociceptor sensitization mediated by interleukin-1beta-primed annulus fibrosus cells
PurposeThis study aims to analyze the effect of pro-inflammatory cytokine-stimulated human annulus fibrosus cells (hAFCs) on the sensitization of...
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Intra-dural intercommunications between dorsal roots of adjacent spinal nerves and their clinical significance
PurposeThe dorsal roots of adjacent spinal nerves are known to communicate with each other through rami communicantes. These intercommunications can...
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Chronic intractable lumbosacral radicular pain, is there a remedy? Pulsed radiofrequency treatment and volumetric modifications of the lumbar dorsal root ganglia
PurposeEvaluation of clinical and radiological effects of the therapeutic outcome of CT-guided pulsed radiofrequency (PRF) treatment adjacent to the...