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Histopathological Evaluation and Molecular Diagnostic Tests for Peritoneal Metastases with Unknown Primary Site—a Review
Cancer of unknown primary (CUP) is a well-studied entity with guidelines available for the management of patients with CUP. The peritoneum represents...
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Implementation of tuberculosis and cryptococcal meningitis rapid diagnostic tests amongst patients with advanced HIV at Kamuzu Central Hospital, Malawi, 2016–2017
BackgroundCryptococcal meningitis (CM) and tuberculosis (TB) remain leading causes of hospitalization and death amongst people living with HIV,...
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The potential impact of Covid-19 on the capacity of routine laboratory tests to detect heparin-induced thrombocytopenia
In Covid-19, anticoagulation with heparin is often administered to prevent or treat thromboembolic events. Heparin-induced thrombocytopenia (HIT) is...
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Diagnostic delays in systemic vasculitides
Systemic vasculitides are among the less common disorders encountered in routine rheumatology practice. The low incidence and heterogeneous...
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Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery
PurposeThis study aimed to ascertain the diagnostic accuracy of non-invasive liver function tests in liver fibrosis and assess their changes after...
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Validation of an autonomous artificial intelligence–based diagnostic system for holistic maculopathy screening in a routine occupational health checkup context
PurposeThis study aims to evaluate the ability of an autonomous artificial intelligence (AI) system for detection of the most common central retinal...
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Malaria rapid diagnostic tests for the case management of febrile children in Nigerian primary healthcare settings: a cross-sectional study
BackgroundMalaria has been identified as a significant public health burden, exhibiting a high risk of death and morbidity. In sub-Saharan Africa,...
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Association Between Health System Factors and Utilization of Routine Laboratory Tests in Clinical Teaching Units: a Cohort Analysis
BackgroundFew studies have looked at health system factors associated with laboratory test use.
ObjectiveTo determine the association between health...
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Influenza colloidal gold method and blood routine tests combination for rapid diagnosis of influenza: a decision tree-based analysis
Rapid influenza diagnosis can facilitate targeted treatment and reduce antibiotic misuse. However, diagnosis efficacy remains unclear. This study...
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Clinic-based evaluation of point-of-care dual HIV/syphilis rapid diagnostic tests at primary healthcare antenatal facilities in South Africa and Zambia
BackgroundSouthern African countries have the largest global burden of HIV and syphilis, with a high prevalence among women of reproductive age....
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Quality of care in patients with hypertension: a retrospective cohort study of primary care routine data in Germany
BackgroundHypertension is a leading cause of morbidity and mortality if not properly managed. Primary care has a major impact on these outcomes if...
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Diagnostic testing practices for diarrhoeal cases in South African public hospitals
BackgroundStool samples submitted for diagnostic testing represent a proportion of diarrhoeal cases seeking healthcare, and an even smaller...
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Routine Upper Gastrointestinal Series Post-bariatric Surgery: Predictors, Usage, and Utility
ObjectiveTo investigate usage and utility of routine upper gastrointestinal (UGI) series in the immediate post-operative period to evaluate for leak...
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Routine Functional Testing or Standard Care in High-Risk Patients after Percutaneous Coronary Intervention
Purpose of ReviewThis review aimed to collate the available evidence on outcomes following routine functional stress testing vs standard of care...
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Is Routine Post-operative Biological Laboratory Assessment Necessary After Sleeve Gastrectomy?
BackgroundIncidence of post-operative complications after sleeve gastrectomy (SG) is low. However, the early identification of these complications...
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Explaining multivariate molecular diagnostic tests via Shapley values
BackgroundMachine learning (ML) can be an effective tool to extract information from attribute-rich molecular datasets for the generation of...
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Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to predict male fertility...
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Added value of an artificial intelligence algorithm in reducing the number of missed incidental acute pulmonary embolism in routine portal venous phase chest CT
ObjectivesThe purpose of this study was to evaluate the incremental value of artificial intelligence (AI) compared to the diagnostic accuracy of...
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Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular testing in breast cancer gained increasing attention and importance as specific molecular results can tailor not only oncological decisions...
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Diagnostic odyssey in amyotrophic lateral sclerosis: diagnostic criteria and reality
BackgroundDiagnosing a rare disease, such as amyotrophic lateral sclerosis, is a major challenge for physicians and patients. Despite detailed...
