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Showing 21-40 of 373 results
  1. Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies

    The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major public health burden worldwide. The most common form of NCD is...

    Article Open access 27 May 2023
  2. Chronic myeloid leukemia stem cells

    Chronic myeloid leukemia (CML) is caused by BCRABL1 in a cell with the biological potential, intrinsic or acquired, to cause leukemia. This cell is...

    Mohammad Houshmand, Giorgia Simonetti, ... Robert Peter Gale in Leukemia
    Article Open access 24 May 2019
  3. Controlled drug delivery vehicles for cancer treatment and their performance

    Although conventional chemotherapy has been successful to some extent, the main drawbacks of chemotherapy are its poor bioavailability, high-dose...

    Sudipta Senapati, Arun Kumar Mahanta, ... Pralay Maiti in Signal Transduction and Targeted Therapy
    Article Open access 16 March 2018
  4. Inflammation and tumor progression: signaling pathways and targeted intervention

    Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially...

    Huakan Zhao, Lei Wu, ... Yongsheng Li in Signal Transduction and Targeted Therapy
    Article Open access 12 July 2021
  5. Review on antioxidants and evaluation procedures

    Antioxidants are the substances that are capable of counteracting the damaging effects of the physiological process of oxidation occur in animal...

    Suresh Kumar, Sunil Sharma, Neeru Vasudeva in Chinese Journal of Integrative Medicine
    Article 06 October 2017
  6. Abstracts

    Article 20 March 2024
  7. Cysteinyl-glycine reduces mucosal proinflammatory cytokine response to fMLP in a parenterally-fed piglet model

    Background:

    PepT1 transports dietary and bacterial peptides in the gut. We hypothesized that cysteinyl-glycine would ameliorate the inflammatory...

    Matthew G. Nosworthy, Janet A. Brunton in Pediatric Research
    Article 07 April 2016
  8. Nod2–Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats

    Background and Aims

    PepT1 can transport bacterial oligopeptide products and induce intestinal inflammation. Our aim was to investigate the mechanism...

    Guoguang Ma, Bin Shi, ... Wanhua Yang in Digestive Diseases and Sciences
    Article 03 July 2015
  9. Site-Specifically Labeled Immunoconjugates for Molecular Imaging—Part 1: Cysteine Residues and Glycans

    Due to their remarkable selectivity and specificity for cancer biomarkers, immunoconjugates have emerged as extremely promising vectors for the...

    Pierre Adumeau, Sai Kiran Sharma, ... Brian M. Zeglis in Molecular Imaging and Biology
    Article Open access 11 January 2016
  10. An insight into the potentially old-wonder molecule—quercetin: the perspectives in foresee

    Use of phyto-medicine and digitalization of phyto-compounds has been fallen enthralling field of science in recent years. Quercetin, a flavonoid with...

    Nidhi Rani, Lakshmi Palanisamy Thanga Velan, ... Annamalai Arunachalam in Chinese Journal of Integrative Medicine
    Article 09 September 2015
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