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An Early Cost-Utility Model of mRNA-Based Therapies for the Treatment of Methylmalonic and Propionic Acidemia in the United Kingdom
Background and ObjectiveNovel messenger RNA (mRNA)-based therapies, currently in development, are emerging as a promising potential treatment...
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Long-term cost-utility analysis of family therapy vs. treatment as usual for young people seen after self-harm
BackgroundThe joint evidence of the cost and the effectiveness of family-based therapies is modest.
ObjectiveTo study the cost-effectiveness of...
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Cost-utility of vitamin D supplementation to prevent acute respiratory infections in children
IntroductionIncreasing evidence has demonstrated the effectiveness and safety of vitamin D supplementation to prevent acute respiratory infections in...
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Lateral lumbar interbody fusion (LLIF) reduces total lifetime cost compared with posterior lumbar interbody fusion (PLIF) for single-level lumbar spinal fusion surgery: a cost-utility analysis in Thailand
BackgroundLumbar interbody fusion techniques treat degenerative lumbar diseases effectively. Minimally invasive lateral lumbar interbody fusion...
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A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
BackgroundOlder adults are at greater risk of medication-related harm than younger adults. The Integrated Medication Management model is an...
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Culturally sensitive stepped care for adolescent refugees: efficacy and cost–utility of a multicentric randomized controlled trial
Adolescent refugees and asylum seekers (ARAS) are highly vulnerable to mental health problems. Stepped care models (SCM) and culturally sensitive...
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Cost-utility analysis of TAVI compared with surgery in patients with severe aortic stenosis at low risk of surgical mortality in the Netherlands
BackgroundThere is growing evidence to support the benefits of transcatheter aortic valve implantation (TAVI) over surgical aortic valve replacement...
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Cost-Utility Analysis of Pegaspargase for the Treatment of Acute Lymphoblastic Leukemia in Greece
Background and ObjectiveAcute lymphoblastic leukemia (ALL) is an acute, rapidly progressing and life-threatening form of cancer involving immature...
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Cost-Utility Analysis of Esketamine for Patients with Treatment-Resistant Depression in Italy
AimMajor depressive disorder is considered one of the most frequent diseases in the general population, and treatment-resistant depression (TRD)...
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Cost-utility analysis of a supervised exercise intervention for women with early-stage endometrial cancer
PurposeCardiovascular disease (CVD) is the leading cause of death after treatment for endometrial cancer (EC). There is clinical evidence that...
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OM-85 BV in pediatric recurrent respiratory tract infections: a cost-utility analysis
BackgroundDespite the growing evidence on efficacy, little is known regarding the cost-utility of Vaxom/Imocur (OM-85 BV) supplementation to decrease...
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Model-based cost-utility analysis of gemcitabine, cisplatin, and S-1 as triple therapy for advanced biliary tract cancer
BackgroundThe results of the KHBO1401-MITSUBA trial suggest the effectiveness of triple therapy using gemcitabine, cisplatin, and S-1; however, the...
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A cost-utility analysis comparing endovascular coiling to neurosurgical clip** in the treatment of aneurysmal subarachnoid haemorrhage
Endovascular coiling (EC) has been identified in systematic reviews and meta-analyses to produce more favourable clinical outcomes in comparison to...
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A Systematic Review of Methods Used by Pediatric Cost-Utility Analyses to Include Family Spillover Effects
BackgroundA child’s health condition affects family members’ health and well-being. However, pediatric cost-utility analysis (CUA) commonly ignores...
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Optimising Alzheimer’s Disease Diagnosis and Treatment: Assessing Cost-Utility of Integrating Blood Biomarkers in Clinical Practice for Disease-Modifying Treatment
BackgroundRecent developments in blood biomarkers (BBM) have shown promising results in diagnosing amyloid pathology in Alzheimer’s Disease (AD)....
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Podotimod in pediatric recurrent respiratory tract infections: a cost-utility analysis
IntroductionDespite the growing evidence on efficacy, few economic evaluations have evaluated the cost-utility of Pidotimod (PDT) supplementation to...
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Model and Empirical Data-Based Cost-Utility Studies of Continuous Glucose Monitoring in Individuals with Type 1 Diabetes: A Protocol of a Systematic Review on Methodology and Quality
IntroductionThis review aims to critically appraise differences in methodology and quality of model-based and empirical-data-based cost-utility...
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Eligibility and Cost-Utility Analysis of Dapagliflozin in Patients with Heart Failure Across the Whole Spectrum of Ejection Fraction in South Korea
BackgroundThe DAPA-HF and DELIVER trials demonstrated the clinical benefits of dapagliflozin in heart failure (HF) patients across the entire...
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Cost-effectiveness and cost-utility of the ball-and-socket trapeziometacarpal prosthesis compared to trapeziectomy and ligament reconstruction: study protocol for a randomized controlled clinical trial
BackgroundTrapeziometacarpal (TMC) osteoarthritis (OA) is a common cause of pain and weakness during thumb pinch leading to disability. There is no...
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Cost-utility analysis of caspofungin and fluconazole for primary treatment of invasive candidiasis and candidemia in Ethiopia
BackgroundInvasive candidiasis and/or candidemia (IC/C) is a common fungal infection leading to significant health and economic losses worldwide....