Search
Search Results
-
A protocol for the Development of Core Outcome Sets for Endodontic Treatment modalities (COSET): an international consensus process
BackgroundThe outcome of endodontic treatment is generally assessed using a range of patient and clinician-centred, non-standardised clinical and...
-
A core outcome set for randomised controlled trials of physical activity interventions: development and challenges
BackgroundCore outcome sets are standardised sets of outcomes that should be collected and reported for all clinical trials. They have been widely...
-
Patient and family engagement in the development of core outcome sets for two rare chronic diseases in children
BackgroundCore outcome sets (COS) are lists of consensus-determined outcomes to be measured and reported in all clinical research studies within a...
-
Development of an international core outcome set for treatment trials in necrotizing enterocolitis—a study protocol
AimNecrotizing enterocolitis (NEC) is the most lethal disease of the gastrointestinal tract of preterm infants. New and existing management...
-
Implementation of the HOME core outcome set for clinical trials of atopic eczema—barriers and opportunities: the HOME IX meeting report
The Harmonising Outcome Measures for Eczema (HOME) initiative established a core outcome set (COS) for atopic eczema (AE) clinical trials in 2019....
-
Protocol for the development of an international Core Outcome Set for treatment trials in adults with epilepsy: the EPilepsy outcome Set for Effectiveness Trials Project (EPSET)
BackgroundA Core Outcome Set (COS) is a standardised list of outcomes that should be reported as a minimum in all clinical trials. In epilepsy, the...
-
The Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) study: International consensus on outcome measures for trials of interventions for adults with single-sided deafness
BackgroundSingle-sided deafness (SSD) has functional, psychological, and social consequences. Interventions for adults with SSD include hearing aids...
-
Dental antibiotic stewardship: study protocol for develo** international consensus on a core outcome set
BackgroundAntimicrobial resistance is both a global public health and patient safety problem driven by overprescribing of antibiotic and other...
-
Quality assessment of outcome reporting, publication characteristics and overall methodological quality in trials on synthetic mesh procedures for the treatment of pelvic organ prolapse for development of core outcome sets
Introduction and hypothesisVariations in outcome measures and reporting of outcomes in trials on surgery for pelvic organ prolapse (POP) using...
-
Core outcome set for early intervention trials to prevent obesity in childhood (COS-EPOCH): Agreement on “what” to measure
BackgroundHeterogeneity in the outcomes collected and reported in trials of interventions to prevent obesity in the first five years of life...
-
Patient-Centered Core Impact Sets: What They are and Why We Need Them
A quote attributed to Mark Twain states, “What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The...
-
Validation of patient- and GP-reported core sets of quality indicators for older adults with multimorbidity in primary care: results of the cross-sectional observational MULTIqual validation study
BackgroundOlder adults with multimorbidity represent a growing segment of the population. Metrics to assess quality, safety and effectiveness of care...
-
COS-Speech: protocol to develop a core outcome set for dysarthria after stroke for use in clinical practice and research
BackgroundDysarthria after stroke is when speech intelligibility is impaired, and this occurs in half of all stroke survivors. Dysarthria often leads...
-
Improvements and advances in core outcome set methodology: proceedings of the CS-COUSIN & COMFA Joint Meeting
A COS is a systematically developed list of outcomes recommended for reporting all studies within a particular disease area. The Cochrane Skin–Core...
-
A protocol for develo** a core outcome set for ectopic pregnancy
BackgroundRandomised controlled trials (RCTs) evaluating ectopic pregnancy have reported many different outcomes, which are themselves often defined...
-
Core outcome sets in cancer and their approaches to identifying and selecting patient-reported outcome measures: a systematic review
ObjectivesIssues arising from a lack of outcome standardisation in health research may be addressed by the use of core outcome sets (COS), which...
-
The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum
IntroductionPyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that affects approximately 0.3–6 out of every 100,000 people worldwide....
-
Factors associated with reporting of the Prevention of Falls Network Europe (ProFaNE) core outcome set domains in randomized trials on falls in older people: a citation analysis and correlational study
BackgroundCore outcome sets are advocated as a means to standardize outcome reporting across randomized controlled trials (RCTs) and reduce selective...
-
The CORE-KDT study: a mixed methods protocol to establish core outcomes for refractory childhood epilepsy treated with ketogenic diet therapy
BackgroundA core outcome set defines the minimum outcomes that should be included in clinical trials, audit or practice. The aim being to increase...