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Showing 21-40 of 2,224 results
  1. Tendon stem/progenitor cells are promising reparative cell sources for multiple musculoskeletal injuries of concomitant articular cartilage lesions associated with ligament injuries

    Background

    Trauma-related articular cartilage lesions usually occur in conjunction with ligament injuries. Torn ligaments are frequently reconstructed...

    Heyong Yin, Kelei Mao, ... Lin Shi in Journal of Orthopaedic Surgery and Research
    Article Open access 15 November 2023
  2. Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development

    The 5′-HOXD genes are important for chondrogenesis in vertebrates, but their roles in osteoarthritis (OA) are still ambiguous. In our study, 5′-HOXD ...

    Quan Hong, Zhong-Xun Liu, ... Bo Yu in Journal of Orthopaedic Surgery and Research
    Article Open access 02 February 2024
  3. Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogenesis

    Fractures are frequently occurring diseases that endanger human health. Crucial to fracture healing is cartilage formation, which provides a...

    Hui Xue, Dike Tao, ... Yao Sun in Frontiers of Medicine
    Article 08 May 2019
  4. Pannexins in the musculoskeletal system: new targets for development and disease progression

    During cell differentiation, growth, and development, cells can respond to extracellular stimuli through communication channels. Pannexin (Panx)...

    Yan Luo, Shengyuan Zheng, ... Yusheng Li in Bone Research
    Article Open access 06 May 2024
  5. Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice

    Background

    Primary osteoarthritis (OA) occurs without identifiable underlying causes such as previous injuries or specific medical conditions. Age is...

    Sher Bahadur Poudel, Ryan R. Ruff, ... Shoshana Yakar in Arthritis Research & Therapy
    Article Open access 08 June 2024
  6. The effect of hypoxia on chondrogenesis of equine synovial membrane-derived and bone marrow-derived mesenchymal stem cells

    Background

    Joint injury is extremely common in equine athletes and post-traumatic osteoarthritis (PTOA), a progressive and debilitating disease, is...

    Alexis L. Gale, Renata M. Mammone, ... Kyla F. Ortved in BMC Veterinary Research
    Article Open access 14 June 2019
  7. Articular cartilage repair using autologous collagen-induced chondrogenesis (ACIC): a pragmatic and cost-effective enhancement of a traditional technique

    Purpose

    The autologous collagen-induced chondrogenesis technique is described, and the results of a 6-year follow-up clinical study using this...

    Seok Jung Kim, Asode Ananthram Shetty, ... Sang Heon Lee in Knee Surgery, Sports Traumatology, Arthroscopy
    Article 17 February 2020
  8. Sustained benefit of autologous matrix-induced chondrogenesis for hip cartilage repair in a recreational athletic population

    Purpose

    To investigate the clinical outcome of autologous matrix-induced chondrogenesis (AMIC) implementation for mid-sized chondral lesions of the...

    Fritz Thorey, Michael-Alexander Malahias, Dimitrios Giotis in Knee Surgery, Sports Traumatology, Arthroscopy
    Article 28 November 2019
  9. Palovarotene: First Approval

    Palovarotene (Sohonos™) is an orally bioavailable selective retinoic acid receptor (RAR)γ agonist being developed by Ipsen for the reduction of...

    Sheridan M. Hoy in Drugs
    Article 06 April 2022
  10. Characteristics of gene expression in frozen shoulder

    Background

    Severe frozen shoulder (FS) is often resistant to treatment and can thus result in long-term functional impairment. However, its etiology...

    Hiroaki Nishimoto, Shoji Fukuta, ... Tetsuo Yamaguchi in BMC Musculoskeletal Disorders
    Article Open access 25 August 2022
  11. Do Interactions of Vitamin D3 and BMP Signaling Hold Implications in the Pathogenesis of Fibrodysplasia Ossificans Progressiva?

    Purpose of Review

    Fibrodysplasia ossificans progressiva (FOP) is a debilitating rare disease known for episodic endochondral heterotopic ossification...

    Jessica L. Pierce, Daniel S. Perrien in Current Osteoporosis Reports
    Article 14 April 2021
  12. SPECT/CT imaging features of cystic degeneration of the talus and their relation to pathological findings

    Background

    Osteochondral lesions of the talus (OLTs) are a common orthopedic condition. The image presentation is very similar to that of ischemic...

    Qitao Song, **antie Zeng, ... **nlong Ma in Journal of Orthopaedic Surgery and Research
    Article Open access 12 October 2022
  13. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair

    Chondrocyte differentiation is a critical process for endochondral ossification, which is responsible for long bone development and fracture repair....

    Rui Shao, Zhong Zhang, ... Weiguo Zou in Bone Research
    Article Open access 07 June 2021
  14. Low-intensity photobiomodulation at 632.8 nm increases tgfβ3, col2a1, and sox9 gene expression in rat bone marrow mesenchymal stem cells in vitro

    The high incidence of cartilage destructions, as well as the social and economic importance of this pathology attracted great interest to the...

    M. S. Bozhokin, D. B. Vcherashnii, ... M. G. Khotin in Lasers in Medical Science
    Article 26 February 2021
  15. Limited evidence in support of bone marrow aspirate concentrate as an additive to the bone marrow stimulation for osteochondral lesions of the talus: a systematic review and meta-analysis

    Purpose

    Bone marrow aspirate concentrate can be used as an additive to surgical treatment of osteochondral lesions of the talus. This systematic...

    Chiel Klein, Jari Dahmen, ... Gino M. M. J. Kerkhoffs in Knee Surgery, Sports Traumatology, Arthroscopy
    Article 14 November 2023
  16. CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

    Objective

    Synovial fibroblasts (SFs) in rheumatoid arthritis (RA) and osteoarthritis (OA) play biphasic roles in joint destruction and regeneration of...

    Seiji Noda, Tadashi Hosoya, ... Shinsuke Yasuda in Arthritis Research & Therapy
    Article Open access 15 February 2022
  17. Fgfr1 conditional-knockout in neural crest cells induces heterotopic chondrogenesis and osteogenesis in mouse frontal bones

    Most facial bones, including frontal bones, are derived from neural crest cells through intramembranous ossification. Fibroblast growth factor...

    Mariko Kawai, David Herrmann, ... Kiyoshi Ohura in Medical Molecular Morphology
    Article 29 November 2018
  18. Hyaluronic Acid Dermal Filler Promotes Cartilage Resha** in Rabbit Ears

    Background

    Neonatal ear is more malleable and soft, allowing the correction of deformities by using external molding. This is mainly attributed to...

    Nazım Gümüş, M. Baver Acaban, Hatice Oruç Demirbağ in Aesthetic Plastic Surgery
    Article 01 April 2022
  19. Nanotechnology development in surgical applications: recent trends and developments

    This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigate the use of nanotechnology in...

    Farzad Abaszadeh, Muhammad Hossein Ashoub, ... Mahnaz Amiri in European Journal of Medical Research
    Article Open access 24 November 2023
  20. Recent progress on the role of miR-140 in cartilage matrix remodelling and its implications for osteoarthritis treatment

    Cartilage matrix remodelling homeostasis is a crucial factor in maintaining cartilage integrity. Loss of cartilage integrity is a typical...

    Li Duan, Yujie Liang, ... Da** Wang in Arthritis Research & Therapy
    Article Open access 18 August 2020
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