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Risk factors and prognosis of malignant peritoneal mesothelioma with paraneoplastic syndrome
BackgroundMalignant peritoneal mesothelioma (MPM) is a rare and highly aggressive tumor. Its clinical manifestations are diverse, and the symptoms...
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Cheminformatics identification of modulators of key carbohydrate-metabolizing enzymes from C. cujete for type-2 diabetes mellitus intervention
PurposeThe therapeutic use of oral hypoglycaemic agents in the management of type-2 diabetes mellitus (T2DM) is without adverse effects; thus, calls...
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The Significance of Serum Tumor Markers CEA, Ca 19–9, Ca 125, Ca 15–3, and AFP in Patients Scheduled for Orthotopic Liver Transplantation: Do Elevated Levels Really Mean Malignancy?
Aim and BackgroundPreparation of the patients for liver transplantation is a meticulous process and includes evaluation of tumor markers to rule out...
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Predicting pathologic complete response in locally advanced rectal cancer patients after neoadjuvant therapy: a machine learning model using XGBoost
PurposeWatch and wait strategy is a safe and effective alternative to surgery in patients with locally advanced rectal cancer (LARC) who have...
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Prognostic impact of pre- and postoperative tumor markers in patients with intrahepatic cholangiocarcinoma
PurposeThe present study assessed the impact of pre- and postoperative tumor markers on the survival of patients with intrahepatic...
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Does CA 125 Predict Peritoneal Dissemination in Patients with Gastric Cancer?
Peritoneal dissemination is one of the most common forms of metastasis with a poor prognosis in patients with gastric cancer. This study aimed to...
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Biomarkers and the quadriceps femoris muscle architecture assessed by ultrasound in older adults with heart failure with preserved ejection fraction: a cross-sectional study
BackgroundSarcopenia is an important comorbidity in patients with heart failure with preserved ejection fraction (HFpEF). The ultrasound (US)...
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Validation study for prognostic scoring system for perihilar cholangiocarcinoma surgery using preoperative factors
PurposeRecently, systemic inflammatory responses (SIR) have been shown to play a pivotal role in the development and progression of cancer. We...
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Prognostic significance of serum CA125 in the overall management for patients with gastrointestinal stromal tumors
BackgroundCarbohydrate antigen 125 (CA125) is elevated as a tumor marker in many carcinomas, but its association with gastrointestinal stromal tumor...
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Serum CCAT2 as a biomarker for adjuvant diagnosis and prognostic prediction of cervical cancer
Growing evidence indicates that lncRNA colon cancer-associated transcript 2 (CCAT2) is associated with cancers. However, the clinical value of CCAT2...
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Dual-energy CT improves differentiation of non-hypervascular pancreatic neuroendocrine neoplasms from CA 19-9-negative pancreatic ductal adenocarcinomas
PurposeTo evaluate the utility of dual-energy CT (DECT) in differentiating non-hypervascular pancreatic neuroendocrine neoplasms (PNENs) from...
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Evaluation of serum CA125-Tn glycoform in peritoneal dissemination and surgical completeness of high-grade serous ovarian cancer
BackgroundPeritoneal dissemination is the predominant feature of malignant progression in ovarian cancer and is a major cause of poor surgical...
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Predictive value of monocyte to high-density lipoprotein cholesterol ratio and tumor markers in colorectal cancer and their relationship with clinicopathological characteristics
ObjectiveTo evaluate the predictive value of monocyte (M) to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) and tumor markers in colorectal...
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Percutaneous biliary stent with intraluminal brachytherapy versus palliative surgery in the management of extrahepatic cholangiocarcinoma
BackgroundTo compare the efficacy and outcomes of self-expandable metallic stent combined with catheter-loaded iodine-125 seeds (SEMS-CL- 125 I)...
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Prognosis prediction of icotinib as targeted therapy for advanced EGFR-positive non–small cell lung cancer patients
Clinical trials on icotinib, a first-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), have shown promising results...
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Serum KL-6, CA19-9, CA125 and CEA are Diagnostic Biomarkers for Rheumatoid Arthritis-Associated Interstitial Lung Disease in the Chinese Population
IntroductionThis study aimed to evaluate the role of tumor marker carbohydrate antigen (CA) 125 (CA125), CA19-9, carcinoembryonic antigen (CEA) and...
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Recurrent Intrahepatic Cholangiocarcinoma: A 10-Point Score to Predict Post-Recurrence Survival and Guide Treatment of Recurrence
IntroductionAlthough up to 50–70% of patients with intrahepatic cholangiocarcinoma (ICC) recur following resection, data to predict post-recurrence...
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Abdominal aortic calcification volume as a preoperative prognostic predictor for pancreatic cancer
PurposeAtherosclerosis and cancer may progress through common pathological factors. This study was performed to investigate the association between...
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Apatinib treatment efficiently delays biochemical-only recurrent ovarian cancer progression
BackgroundBiochemical recurrence is defined as only rising CA-125 but no radiographic evidence of disease; noteworthily, it generally precedes the...
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Plasma circRNA microarray profiling identifies novel circRNA biomarkers for the diagnosis of ovarian cancer
BackgroundCircular RNA (circRNA), a class of RNA with a covalent closed circular structure that widely existed in serum and plasma, has been...
