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Gallbladder Cancer Current Treatment Options
The book discusses the recent progress in understanding the therapeutic targets for gallbladder cancer to provide opportunities for research and for...
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Local Therapeutics for the Treatment of Oligo Metastatic Prostate Cancer
Purpose of ReviewMetastatic prostate cancer remains universally lethal. Although de-novo metastatic prostate cancer was historically managed with...
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Therapeutic Approaches in Cancer Treatment
This comprehensive book provides an overview of cancer therapeutics and covers different innovative treatment approaches for cancer. The initial...
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Understanding on CRISPR/Cas9 mediated cutting-edge approaches for cancer therapeutics
The research focus on CRISPR/Cas9 has gained substantial concentration since the discovery of ‘an unusual repeat sequence’ reported by Ishino et al....
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Pancreatic Cancer Current Therapeutics and Future Directions
Pancreatic cancer is a challenging and complex disease characterized by a dense fibrotic stroma and an immunosuppressive tumor...
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Digital therapeutics from bench to bedside
As a new therapeutic technique based on digital technology, the commercialization and clinical application of digital therapeutics (DTx) are...
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TNFR2 antagonist and agonist: a potential therapeutics in cancer immunotherapy
Tumour necrosis factor receptor 2 or TNFR2 is considered an appealing target protein due to its limited frequency to TREGs, which are highly...
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Clinical Characteristics, Diagnosis, and Therapeutics of COVID-19: A Review
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that suddenly emerged at the end of December 2019 and caused coronavirus...
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mRNA-based therapeutics: powerful and versatile tools to combat diseases
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide range of incurable diseases. Recent rapid advances in...
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TGF-β signaling in health, disease, and therapeutics
Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can...
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Personalizing approaches to the management of metastatic hormone sensitive prostate cancer: role of advanced imaging, genetics and therapeutics
PurposeTo summarize contemporary and emerging strategies for the diagnosis and management of metastatic hormone sensitive prostate cancer (mHSPC),...
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NK Cell Therapeutics for Hematologic Malignancies: from Potential to Fruition
Purpose of ReviewThe current review focuses on the preclinical development and clinical advances of natural killer (NK) cell therapeutics for...
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TRAIL-mediated signaling in bladder cancer: realization of clinical efficacy of TRAIL-based therapeutics in medical oncology
Bladder cancer is a therapeutically challenging disease and wealth of knowledge has enabled researchers to develop a clear understanding of...
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Innovations in Skin and Soft Tissue Aging—A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes
PurposeSkin and soft tissue aging has been an important topic of discussion among plastic surgeons and their patients. While botulinum toxin, facial...
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Nitro-fatty acids: mechanisms of action, roles in metabolic diseases, and therapeutics
Nitro-fatty acids (NO 2 -FAs) are a class of bioactive lipids that mediate metabolic, anti-oxidative stress, anti-inflammatory, and other signaling...
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Cancer vaccines as promising immuno-therapeutics: platforms and current progress
Research on tumor immunotherapy has made tremendous progress in the past decades, with numerous studies entering the clinical evaluation. The cancer...
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Emerging therapeutics and evolving assessment criteria for intracranial metastases in patients with oncogene-driven non-small-cell lung cancer
The improved survival outcomes of patients with non-small-cell lung cancer (NSCLC), largely owing to the improved control of systemic disease...
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The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
More than 60 years ago, disulfiram (DSF) was employed for the management of alcohol addiction. This promising cancer therapeutic agent inhibits...