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The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades
Progress in the research and therapy of adult acute lymphoblastic leukemia (ALL) is accelerating. This analysis summarizes the data derived from the...
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Polygenic Risk Scores to Identify CVD Risk and Tailor Therapy: Hope or Hype?
Purpose of ReviewThe purpose of this review is to understand the conceptual basis and implications of polygenic risk scores (PRS) in assessing risk...
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A Large Retrospective Cohort Study on the Risk of Alzheimer’s Disease and Related Dementias in Association with Vascular Diseases and Cancer Therapy in Men with Prostate Cancer
BackgroundNo study was conducted on the long-term risk of Alzheimer’s disease (AD) and related dementias (ADRD) in association with vascular diseases...
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Drug therapy problems among hospitalized patients with cardiovascular disease
BackgroundOptimal utilization of cardiovascular drugs is crucial in reducing morbidity and mortality associated with cardiovascular diseases....
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HealthyRHearts - reducing cholesterol in rural adults via telehealth-based medical nutrition therapy: protocol for a cluster randomised controlled trial
BackgroundFew randomised controlled trials specifically focus on prevention in rural populations. Cardiovascular disease (CVD) contributes to...
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Predicted cardiovascular disease risk and prescribing of antihypertensive therapy among patients with hypertension in Australia using MedicineInsight
Hypertension guidelines recommend that absolute cardiovascular disease (CVD) risk guide the management of hypertensive patients. This study aimed to...
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Statin therapy improves outcomes in infective endocarditis: evidence from a meta-analysis
BackgroundBeyond its ability to decrease cholesterol, statin medication has been proved to have a variety of pleiotropic effects, such as...
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25 years of lipid-lowering therapy: secular trends in therapy of coronary patients
Background and aimGuidelines on dyslipidemia and lipid-lowering therapy (LLT) over the years recommend lower low-density lipoprotein cholesterol...
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mHealth Technology and CVD Risk Reduction
Purpose of ReviewTo review existing mHealth-based interventions and examine their efficacy in reducing cardiovascular disease (CVD) risk factors.
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A mobile health application for patients eligible for statin therapy: app development and qualitative feedback on design and usability
BackgroundCardiovascular disease is the leading cause of death in the United States (US). Despite the well-recognized efficacy of statins, statin...
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Association of statin therapy with progression of carotid arterial stiffness: the Multi-Ethnic Study of Atherosclerosis (MESA)
Arterial stiffness progresses with age and is a predictor of adverse cardiovascular disease events. Studies examining associations of statin therapy...
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Factors Associated with Discontinuation of Statin Therapy in Patients with Lymphoma Aged 80 Years and Older: A Retrospective Single-Institute Study
BackgroundThere is little evidence to support or negate the benefits of statin therapy for primary prevention of cardiovascular disease (CVD) in...
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Predictors of Informed People’s Preferences for Statin Therapy to Reduce Cardiovascular Disease Risk: an Internet Survey Study
BackgroundGuidelines suggest clinicians inform patients about their 10-year cardiovascular disease (CVD) risk; however, little is known about how the...
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Lipid-Lowering Therapy in Women of Childbearing Age: a Review and Stepwise Clinical Approach
Purpose of ReviewWomen are less often recognized to have cardiovascular disease (CVD) risk and are underrepresented in randomized trials of...
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Gender Differences in Guideline-Directed Medical Therapy for Cardiovascular Disease Among Young Veterans
BackgroundThere is an increasing burden of cardiovascular disease, including coronary artery disease (CAD) and heart failure (HF), among women...
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The experience of participating in an internet-based cognitive behavioral therapy program among patients with cardiovascular disease and depression: a qualitative interview study
BackgroundDepression in conjunction with cardiovascular disease (CVD) is associated with worsening in CVD, higher mortality, and poorer quality of...
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The effect of a multi-component behavior change technique intervention on medication adherence among individuals on primary prevention statin therapy: a dose-finding protocol
BackgroundIn the USA, the primary cause of death and morbidity continues to be cardiovascular disease (CVD). Numerous trials have shown that statin...
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Real-world effectiveness of early insulin therapy on the incidence of cardiovascular events in newly diagnosed type 2 diabetes
Early insulin therapy is capable to achieve glycemic control and restore β-cell function in newly diagnosed type 2 diabetes (T2D), but its effect on...
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Postmenopausal Osteoporosis: Menopause Hormone Therapy and Selective Estrogen Receptor Modulators
IntroductionOsteoporosis is a debilitating silent disease with a huge socio-economic impact. Prevention strategies and early detection of...
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Efficacy of intensive lipid-lowering therapy with statins stratified by blood pressure levels in patients with type 2 diabetes mellitus and retinopathy: Insight from the EMPATHY study
Intensive lipid-lowering therapy is recommended in individuals exhibiting type 2 diabetes mellitus (T2DM) with microvascular complications (as...
