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LGI-1 encephalopathy following ChAdOx1 nCov-19 vaccination
A 71-year-old male patient was diagnosed with LGI1 encephalopathy 4 weeks following a first ChAdOx1 nCov-19 vaccination. Extensive work-up including...
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Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: possible therapeutic intervention of rutin and quercetin
Diabetic nephropathy and peripheral neuropathy are the two main complications of chronic diabetes that contribute to high morbidity and mortality....
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Seizures in the Setting of COVID-19
Purpose of reviewThis review presents current available data relating to seizures in the context of COVID-19 infection from theorized pathophysiology...
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Non-rigid motion-corrected free-breathing 3D myocardial Dixon LGE imaging in a clinical setting
ObjectivesTo investigate the efficacy of an in-line non-rigid motion-compensated reconstruction (NRC) in an image-navigated high-resolution...
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REM Behavior Disorder: Implications for PD Therapeutics
PurposeRapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that occurs during REM sleep, characterized by REM sleep without atonia...
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Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects
BackgroundMigraine occurs 2–3 times more often in females than in males and is in many females associated with the onset of menstruation. The steroid...
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Anticonvulsive treatment in autoimmune encephalitis: a systematic literature review
BackgroundEpileptic seizures are a common manifestation of autoimmune encephalitis (AIE). Immunosuppression (IT) is an efficient therapeutic...
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Neuronal autoantibodies in a sample of Egyptian patients with drug-resistant epilepsy
BackgroundEpilepsy is one of the most common and chronic neurological diseases. About one-third of epilepsy patients do not achieve seizure freedom...
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Neurofascin antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: from intrinsic genetic background to clinical manifestations
There are bunch of autoantibodies, particularly autoantibodies against proteins located at the node of Ranvier, have been discovered and transformed...
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Language impairments in seropositive and seronegative autoimmune encephalitis
Background and objectiveAutoimmune encephalitis (AE) is a rare neuroinflammatory disease affecting the central nervous system. To examine language...
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Nodes of Ranvier during development and repair in the CNS
Saltatory conduction of action potentials along myelinated axons depends on the nodes of Ranvier — small unmyelinated axonal domains where...
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Memory function in autoimmune encephalitis: a cross-sectional prospective study utilising multiple memory paradigms
Background and objectiveAutoimmune encephalitis (AE) is often associated with clinically significant memory impairment. This study aimed to evaluate...
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Autoimmun-Enzephalitis
We report the case of a patient with CASPR-2-antibody-positive autoimmune encephalitis both in the clinical presentation and laboratory evaluation....
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The three pillars in treating antibody-mediated encephalitis
The rapid initiation of immunotherapy has a decisive impact on the course of the disease in patients with antibody-mediated encephalitis (AE). The...
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Acute neurological disease as a trigger or co-occurrence of transient global amnesia: a case series and systematic review
BackgroundTransient global amnesia (TGA) represents a benign neurological syndrome of unknown pathophysiology, often accompanied by vanishing...
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Dopamine-2 receptor antibody encephalitis presenting as pure tongue-biting in a tourette syndrome patient: a case report
BackgroundTourette syndrome (TS) is a neuropsychiatric disorder characterized by repetitive and patterned tics. Its onset correlates with...
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The spectrum of anti-GQ1B antibody syndrome: beyond Miller Fisher syndrome and Bickerstaff brainstem encephalitis
IntroductionSince the initial identification of Miller Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis (BBE),significant milestones have...
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Paraneoplastic encephalomyeloradiculits with multiple autoantibodies against ITPR-1, GFAP and MOG: case report and literature review
BackgroundRecently, antibodies against the alpha isoform of the glial-fibrillary-acidic-protein (GFAPα) were identified in a small series of patients...